ZA975266B - Modified form of the R(-)-N-(4,4-Dl(3-methylthien-2-yl)but-3-enyl)- nipecotic acid hydrochloride. - Google Patents

Modified form of the R(-)-N-(4,4-Dl(3-methylthien-2-yl)but-3-enyl)- nipecotic acid hydrochloride.

Info

Publication number
ZA975266B
ZA975266B ZA9705266A ZA975266A ZA975266B ZA 975266 B ZA975266 B ZA 975266B ZA 9705266 A ZA9705266 A ZA 9705266A ZA 975266 A ZA975266 A ZA 975266A ZA 975266 B ZA975266 B ZA 975266B
Authority
ZA
South Africa
Prior art keywords
methylthien
enyl
modified form
acid hydrochloride
nipecotic acid
Prior art date
Application number
ZA9705266A
Other languages
English (en)
Inventor
Preben Ahrndt
Henning Borge Petersen
Vincent H Chang
Kimberly Ann Allen
Michael H Cain
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of ZA975266B publication Critical patent/ZA975266B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9705266A 1996-06-14 1997-06-13 Modified form of the R(-)-N-(4,4-Dl(3-methylthien-2-yl)but-3-enyl)- nipecotic acid hydrochloride. ZA975266B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK66196 1996-06-14

Publications (1)

Publication Number Publication Date
ZA975266B true ZA975266B (en) 1998-02-04

Family

ID=8096101

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9705266A ZA975266B (en) 1996-06-14 1997-06-13 Modified form of the R(-)-N-(4,4-Dl(3-methylthien-2-yl)but-3-enyl)- nipecotic acid hydrochloride.

Country Status (20)

Country Link
EP (1) EP0906309B1 (cs)
JP (1) JP2000511909A (cs)
CN (1) CN1636565A (cs)
AR (1) AR008236A1 (cs)
AT (1) ATE223405T1 (cs)
AU (1) AU723267B2 (cs)
BR (1) BR9709725A (cs)
CZ (1) CZ295578B6 (cs)
DE (1) DE69715196T2 (cs)
DK (1) DK0906309T3 (cs)
ES (1) ES2181002T3 (cs)
HU (1) HUP9904035A3 (cs)
IL (1) IL127469A (cs)
NO (1) NO316889B1 (cs)
PL (1) PL190858B1 (cs)
PT (1) PT906309E (cs)
RU (1) RU2177478C2 (cs)
UA (1) UA52661C2 (cs)
WO (1) WO1997047619A1 (cs)
ZA (1) ZA975266B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914333A (en) * 1996-07-31 1999-06-22 Novo Nordisk A/S Treatment of psychotic disorders
IE970588A1 (en) 1997-08-01 2000-08-23 Elan Corp Plc Controlled release pharmaceutical compositions containing tiagabine
CA2299464C (en) * 1997-08-01 2009-02-17 Elan Corporation, Plc Controlled release pharmaceutical compositions containing tiagabine
CN1314684C (zh) * 2003-12-24 2007-05-09 中国科学院上海有机化学研究所 噻加宾及其消旋体和s－构型的合成方法及其无定形粉末的制法
GB0402118D0 (en) * 2004-01-30 2004-03-03 Merck Sharp & Dohme Polymorphic forms of a GABAA agonist
WO2005092886A1 (en) * 2004-03-29 2005-10-06 Ranbaxy Laboratories Limited Process for the preparation of amorphous form of tiagabine
US20080064727A1 (en) * 2006-08-18 2008-03-13 Cephalon, Inc. Crystalline forms of tiagabine hydrochloride

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK288385D0 (da) * 1985-06-26 1985-06-26 Novo Industri As Aminosyrederivater
DK58291D0 (da) * 1991-04-02 1991-04-02 Novo Nordisk As Krystalinsk stof og dets fremstilling
US5750140A (en) * 1994-05-20 1998-05-12 Novo Nordisk A/S Transdermal delivery of tiagabine

Also Published As

Publication number Publication date
CN1636565A (zh) 2005-07-13
BR9709725A (pt) 1999-08-10
EP0906309A1 (en) 1999-04-07
DE69715196T2 (de) 2003-05-15
RU2177478C2 (ru) 2001-12-27
AU3165397A (en) 1998-01-07
EP0906309B1 (en) 2002-09-04
PL330424A1 (en) 1999-05-10
CZ295578B6 (cs) 2005-08-17
AU723267B2 (en) 2000-08-24
UA52661C2 (uk) 2003-01-15
AR008236A1 (es) 1999-12-29
PT906309E (pt) 2002-12-31
NO316889B1 (no) 2004-06-14
NO985809L (no) 1998-12-11
HUP9904035A2 (hu) 2000-05-28
ES2181002T3 (es) 2003-02-16
IL127469A0 (en) 1999-10-28
DK0906309T3 (da) 2002-12-16
CZ401998A3 (cs) 1999-06-16
JP2000511909A (ja) 2000-09-12
NO985809D0 (no) 1998-12-11
PL190858B1 (pl) 2006-02-28
IL127469A (en) 2001-01-11
ATE223405T1 (de) 2002-09-15
HUP9904035A3 (en) 2000-07-28
DE69715196D1 (de) 2002-10-10
WO1997047619A1 (en) 1997-12-18

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