DK0906309T3 - Modificeret form af R(-)-N-(4,4-di(3-methylthien-2-yl)but-3-enyl)nipecotinsyre-hydrochloridet - Google Patents

Modificeret form af R(-)-N-(4,4-di(3-methylthien-2-yl)but-3-enyl)nipecotinsyre-hydrochloridet

Info

Publication number
DK0906309T3
DK0906309T3 DK97927006T DK97927006T DK0906309T3 DK 0906309 T3 DK0906309 T3 DK 0906309T3 DK 97927006 T DK97927006 T DK 97927006T DK 97927006 T DK97927006 T DK 97927006T DK 0906309 T3 DK0906309 T3 DK 0906309T3
Authority
DK
Denmark
Prior art keywords
methylthien
enyl
modified form
acid hydrochloride
nipecotinic acid
Prior art date
Application number
DK97927006T
Other languages
English (en)
Inventor
Henning Borge Petersen
Vincent H Chang
Kimberly Ann Allen
Michael H Chain
Preben Ahrndt
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of DK0906309T3 publication Critical patent/DK0906309T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK97927006T 1996-06-14 1997-06-03 Modificeret form af R(-)-N-(4,4-di(3-methylthien-2-yl)but-3-enyl)nipecotinsyre-hydrochloridet DK0906309T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK66196 1996-06-14
PCT/DK1997/000244 WO1997047619A1 (en) 1996-06-14 1997-06-03 Modified form of the r(-)-n-(4,4-di(3-methylthien-2-yl)but-3-enyl)-nipecotic acid hydrochloride

Publications (1)

Publication Number Publication Date
DK0906309T3 true DK0906309T3 (da) 2002-12-16

Family

ID=8096101

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97927006T DK0906309T3 (da) 1996-06-14 1997-06-03 Modificeret form af R(-)-N-(4,4-di(3-methylthien-2-yl)but-3-enyl)nipecotinsyre-hydrochloridet

Country Status (20)

Country Link
EP (1) EP0906309B1 (da)
JP (1) JP2000511909A (da)
CN (1) CN1636565A (da)
AR (1) AR008236A1 (da)
AT (1) ATE223405T1 (da)
AU (1) AU723267B2 (da)
BR (1) BR9709725A (da)
CZ (1) CZ295578B6 (da)
DE (1) DE69715196T2 (da)
DK (1) DK0906309T3 (da)
ES (1) ES2181002T3 (da)
HU (1) HUP9904035A3 (da)
IL (1) IL127469A (da)
NO (1) NO316889B1 (da)
PL (1) PL190858B1 (da)
PT (1) PT906309E (da)
RU (1) RU2177478C2 (da)
UA (1) UA52661C2 (da)
WO (1) WO1997047619A1 (da)
ZA (1) ZA975266B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914333A (en) * 1996-07-31 1999-06-22 Novo Nordisk A/S Treatment of psychotic disorders
EP0991409B1 (en) * 1997-08-01 2002-01-30 ELAN CORPORATION, Plc Controlled release pharmaceutical compositions containing tiagabine
IE970588A1 (en) 1997-08-01 2000-08-23 Elan Corp Plc Controlled release pharmaceutical compositions containing tiagabine
CN1314684C (zh) * 2003-12-24 2007-05-09 中国科学院上海有机化学研究所 噻加宾及其消旋体和s－构型的合成方法及其无定形粉末的制法
GB0402118D0 (en) * 2004-01-30 2004-03-03 Merck Sharp & Dohme Polymorphic forms of a GABAA agonist
WO2005092886A1 (en) * 2004-03-29 2005-10-06 Ranbaxy Laboratories Limited Process for the preparation of amorphous form of tiagabine
US20080064727A1 (en) * 2006-08-18 2008-03-13 Cephalon, Inc. Crystalline forms of tiagabine hydrochloride

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK288385D0 (da) * 1985-06-26 1985-06-26 Novo Industri As Aminosyrederivater
DK58291D0 (da) * 1991-04-02 1991-04-02 Novo Nordisk As Krystalinsk stof og dets fremstilling

Also Published As

Publication number Publication date
IL127469A (en) 2001-01-11
EP0906309A1 (en) 1999-04-07
JP2000511909A (ja) 2000-09-12
CZ401998A3 (cs) 1999-06-16
DE69715196T2 (de) 2003-05-15
ES2181002T3 (es) 2003-02-16
NO985809L (no) 1998-12-11
RU2177478C2 (ru) 2001-12-27
AR008236A1 (es) 1999-12-29
AU723267B2 (en) 2000-08-24
HUP9904035A3 (en) 2000-07-28
ATE223405T1 (de) 2002-09-15
UA52661C2 (uk) 2003-01-15
EP0906309B1 (en) 2002-09-04
NO316889B1 (no) 2004-06-14
PT906309E (pt) 2002-12-31
CZ295578B6 (cs) 2005-08-17
AU3165397A (en) 1998-01-07
WO1997047619A1 (en) 1997-12-18
PL190858B1 (pl) 2006-02-28
PL330424A1 (en) 1999-05-10
HUP9904035A2 (hu) 2000-05-28
NO985809D0 (no) 1998-12-11
DE69715196D1 (de) 2002-10-10
CN1636565A (zh) 2005-07-13
IL127469A0 (en) 1999-10-28
BR9709725A (pt) 1999-08-10
ZA975266B (en) 1998-02-04

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