NO985809L - Modifisert form av R(-)-N-(4,4-di(3-metyltien-2-yl)but-3-enyl)-nipekotinsyrehydrokloridet - Google Patents

Modifisert form av R(-)-N-(4,4-di(3-metyltien-2-yl)but-3-enyl)-nipekotinsyrehydrokloridet

Info

Publication number
NO985809L
NO985809L NO985809A NO985809A NO985809L NO 985809 L NO985809 L NO 985809L NO 985809 A NO985809 A NO 985809A NO 985809 A NO985809 A NO 985809A NO 985809 L NO985809 L NO 985809L
Authority
NO
Norway
Prior art keywords
methylthien
enyl
modified form
acid hydrochloride
nipecotinic acid
Prior art date
Application number
NO985809A
Other languages
English (en)
Other versions
NO985809D0 (no
NO316889B1 (no
Inventor
Preben Ahrndt
Henning B Rge Petersen
Vincent H Chang
Kimberly Ann Allen
Michael H Chain
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO985809D0 publication Critical patent/NO985809D0/no
Publication of NO985809L publication Critical patent/NO985809L/no
Publication of NO316889B1 publication Critical patent/NO316889B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO19985809A 1996-06-14 1998-12-11 Vannfri krystallform av R(-)-N-(4,4-di(3-metyltien-2-yl)but-3-enyl) -nipekotinsyrehydrokloridet, fremgangsmate for fremstilling derav, farmasoytisk preparat som omfatter et slikt krystallinsk salt, og anvendelse av et slikt krystallinsk salt til fremstill NO316889B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK66196 1996-06-14
PCT/DK1997/000244 WO1997047619A1 (en) 1996-06-14 1997-06-03 Modified form of the r(-)-n-(4,4-di(3-methylthien-2-yl)but-3-enyl)-nipecotic acid hydrochloride

Publications (3)

Publication Number Publication Date
NO985809D0 NO985809D0 (no) 1998-12-11
NO985809L true NO985809L (no) 1998-12-11
NO316889B1 NO316889B1 (no) 2004-06-14

Family

ID=8096101

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19985809A NO316889B1 (no) 1996-06-14 1998-12-11 Vannfri krystallform av R(-)-N-(4,4-di(3-metyltien-2-yl)but-3-enyl) -nipekotinsyrehydrokloridet, fremgangsmate for fremstilling derav, farmasoytisk preparat som omfatter et slikt krystallinsk salt, og anvendelse av et slikt krystallinsk salt til fremstill

Country Status (20)

Country Link
EP (1) EP0906309B1 (no)
JP (1) JP2000511909A (no)
CN (1) CN1636565A (no)
AR (1) AR008236A1 (no)
AT (1) ATE223405T1 (no)
AU (1) AU723267B2 (no)
BR (1) BR9709725A (no)
CZ (1) CZ295578B6 (no)
DE (1) DE69715196T2 (no)
DK (1) DK0906309T3 (no)
ES (1) ES2181002T3 (no)
HU (1) HUP9904035A3 (no)
IL (1) IL127469A (no)
NO (1) NO316889B1 (no)
PL (1) PL190858B1 (no)
PT (1) PT906309E (no)
RU (1) RU2177478C2 (no)
UA (1) UA52661C2 (no)
WO (1) WO1997047619A1 (no)
ZA (1) ZA975266B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914333A (en) * 1996-07-31 1999-06-22 Novo Nordisk A/S Treatment of psychotic disorders
AU8643698A (en) * 1997-08-01 1999-02-22 Elan Corporation, Plc Controlled release pharmaceutical compositions containing tiagabine
IE970588A1 (en) 1997-08-01 2000-08-23 Elan Corp Plc Controlled release pharmaceutical compositions containing tiagabine
CN1314684C (zh) * 2003-12-24 2007-05-09 中国科学院上海有机化学研究所 噻加宾及其消旋体和s-构型的合成方法及其无定形粉末的制法
GB0402118D0 (en) * 2004-01-30 2004-03-03 Merck Sharp & Dohme Polymorphic forms of a GABAA agonist
WO2005092886A1 (en) * 2004-03-29 2005-10-06 Ranbaxy Laboratories Limited Process for the preparation of amorphous form of tiagabine
US20080064727A1 (en) * 2006-08-18 2008-03-13 Cephalon, Inc. Crystalline forms of tiagabine hydrochloride

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK288385D0 (da) * 1985-06-26 1985-06-26 Novo Industri As Aminosyrederivater
DK58291D0 (da) * 1991-04-02 1991-04-02 Novo Nordisk As Krystalinsk stof og dets fremstilling

Also Published As

Publication number Publication date
ES2181002T3 (es) 2003-02-16
CZ401998A3 (cs) 1999-06-16
PT906309E (pt) 2002-12-31
EP0906309B1 (en) 2002-09-04
RU2177478C2 (ru) 2001-12-27
NO985809D0 (no) 1998-12-11
DK0906309T3 (da) 2002-12-16
BR9709725A (pt) 1999-08-10
AU723267B2 (en) 2000-08-24
JP2000511909A (ja) 2000-09-12
CZ295578B6 (cs) 2005-08-17
IL127469A (en) 2001-01-11
DE69715196D1 (de) 2002-10-10
ATE223405T1 (de) 2002-09-15
ZA975266B (en) 1998-02-04
UA52661C2 (uk) 2003-01-15
PL330424A1 (en) 1999-05-10
WO1997047619A1 (en) 1997-12-18
AU3165397A (en) 1998-01-07
HUP9904035A3 (en) 2000-07-28
PL190858B1 (pl) 2006-02-28
DE69715196T2 (de) 2003-05-15
EP0906309A1 (en) 1999-04-07
IL127469A0 (en) 1999-10-28
NO316889B1 (no) 2004-06-14
HUP9904035A2 (hu) 2000-05-28
AR008236A1 (es) 1999-12-29
CN1636565A (zh) 2005-07-13

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