ID26573A - Bentuk ke-vi dari 5, 6-dikloro-2-(isopropilamino) 1-(b-l-ribofurasonil)-1h-benzimidazol - Google Patents

Bentuk ke-vi dari 5, 6-dikloro-2-(isopropilamino) 1-(b-l-ribofurasonil)-1h-benzimidazol

Info

Publication number
ID26573A
ID26573A IDW20002037A ID20002037A ID26573A ID 26573 A ID26573 A ID 26573A ID W20002037 A IDW20002037 A ID W20002037A ID 20002037 A ID20002037 A ID 20002037A ID 26573 A ID26573 A ID 26573A
Authority
ID
Indonesia
Prior art keywords
ribofurasonil
isopropilamino
dikloro
benzimidazol
Prior art date
Application number
IDW20002037A
Other languages
English (en)
Inventor
Barry Howard Carter
Anne Hodgson
Lian-Feng Huang
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ID26573A publication Critical patent/ID26573A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052Imidazole radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDW20002037A 1998-04-07 1999-04-01 Bentuk ke-vi dari 5, 6-dikloro-2-(isopropilamino) 1-(b-l-ribofurasonil)-1h-benzimidazol ID26573A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9807355.4A GB9807355D0 (en) 1998-04-07 1998-04-07 Antiviral compound

Publications (1)

Publication Number Publication Date
ID26573A true ID26573A (id) 2001-01-18

Family

ID=10829933

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20002037A ID26573A (id) 1998-04-07 1999-04-01 Bentuk ke-vi dari 5, 6-dikloro-2-(isopropilamino) 1-(b-l-ribofurasonil)-1h-benzimidazol

Country Status (40)

Country Link
US (1) US6482939B1 (id)
EP (1) EP1070078B1 (id)
JP (1) JP2002510702A (id)
KR (1) KR100573635B1 (id)
CN (1) CN1222534C (id)
AP (1) AP2000001946A0 (id)
AR (1) AR014973A1 (id)
AT (1) ATE231517T1 (id)
AU (1) AU753527B2 (id)
BG (1) BG104909A (id)
BR (2) BR9909471A (id)
CA (1) CA2327495C (id)
CO (1) CO5011057A1 (id)
DE (1) DE69905025T2 (id)
DK (1) DK1070078T3 (id)
EA (1) EA002953B1 (id)
EE (1) EE04121B1 (id)
EG (1) EG24597A (id)
ES (1) ES2191429T3 (id)
GB (1) GB9807355D0 (id)
GE (1) GEP20022840B (id)
HK (1) HK1032060A1 (id)
HR (1) HRP20000670B1 (id)
HU (1) HUP0101549A3 (id)
ID (1) ID26573A (id)
IL (2) IL138559A0 (id)
IS (1) IS5634A (id)
MA (1) MA26617A1 (id)
NO (1) NO316896B1 (id)
NZ (1) NZ507012A (id)
OA (1) OA11534A (id)
PE (1) PE20000356A1 (id)
PL (1) PL194752B1 (id)
PT (1) PT1070078E (id)
SI (1) SI1070078T1 (id)
SK (1) SK283735B6 (id)
TR (1) TR200002847T2 (id)
WO (1) WO1999051617A2 (id)
YU (1) YU58600A (id)
ZA (1) ZA200005197B (id)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9807354D0 (en) 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound
GB0008939D0 (en) * 2000-04-11 2000-05-31 Glaxo Group Ltd Process for preparing substituted benzimidazole compounds
EP2265115B1 (en) * 2008-03-12 2012-11-28 Janssen Pharmaceutica, N.V. Combinations of hydroxypyrion compounds and silver compounds
US8546344B2 (en) 2010-10-28 2013-10-01 Viropharma Incorporated Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl)-1H-benzimidazole
US8541391B2 (en) * 2010-10-28 2013-09-24 Viropharma Incorporated Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl-1H-benzimidazole
US8940707B2 (en) 2010-10-28 2015-01-27 Viropharma Incorporated Maribavir isomers, compositions, methods of making and methods of using
WO2023105483A1 (en) * 2021-12-10 2023-06-15 Assembly Biosciences, Inc. Crystalline forms of a 5-aminopyrazole compound useful for treating hbv
WO2024081308A1 (en) 2022-10-12 2024-04-18 Takeda Pharmaceutical Company Limited Method of preparing maribavir

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3399987A (en) 1965-08-02 1968-09-03 United States Borax Chem 2-alkylaminobenzimidazoles as herbicides
CH443777A (de) 1965-08-06 1968-02-15 Agripat Sa Verfahren zum Schützen textiler Keratinfasern vor Insektenfrass und Mittel zur Durchführung dieses Verfahrens
US3655901A (en) 1970-07-30 1972-04-11 Merck & Co Inc Method of inhibiting the formation of phenylethanalamine-n-methyl transferase with 2-aminobenzimidazoles
SE9003151D0 (sv) 1990-10-02 1990-10-02 Medivir Ab Nucleoside derivatives
US5248672A (en) 1990-11-01 1993-09-28 The Regents Of The University Of Michigan Polysubstituted benzimidazole nucleosides as antiviral agents
WO1994008456A1 (en) 1992-10-21 1994-04-28 The Regents Of The University Of Michigan Polysubstituted benzimidazoles as antiviral agents
GB9413724D0 (en) * 1994-07-07 1994-08-24 Wellcome Found Therapeutic nucleosides
GB9600143D0 (en) 1996-01-05 1996-03-06 Wellcome Found Therapeutic compounds
GB2319961A (en) * 1996-12-07 1998-06-10 Glaxo Group Ltd Pharmaceutical composition for treatment of restenosis
GB9807354D0 (en) 1998-04-07 1998-06-03 Glaxo Group Ltd Antiviral compound

Also Published As

Publication number Publication date
SI1070078T1 (en) 2003-08-31
CA2327495C (en) 2009-01-20
HRP20000670B1 (en) 2004-04-30
NO20005003D0 (no) 2000-10-04
DE69905025T2 (de) 2003-10-16
AU753527B2 (en) 2002-10-17
EA200000909A1 (ru) 2001-06-25
NO20005003L (no) 2000-12-06
OA11534A (en) 2004-05-06
AP2000001946A0 (en) 2000-12-31
IS5634A (is) 2000-09-22
HK1032060A1 (en) 2001-07-06
PT1070078E (pt) 2003-06-30
CN1304413A (zh) 2001-07-18
DK1070078T3 (da) 2003-05-19
GEP20022840B (en) 2002-11-25
EA002953B1 (ru) 2002-12-26
TR200002847T2 (tr) 2001-01-22
PL343712A1 (en) 2001-08-27
HUP0101549A3 (en) 2003-07-28
WO1999051617A3 (en) 1999-12-09
BRPI9909471B1 (pt) 2018-11-21
KR100573635B1 (ko) 2006-04-26
PE20000356A1 (es) 2000-04-26
EP1070078A2 (en) 2001-01-24
ES2191429T3 (es) 2003-09-01
BRPI9909471B8 (pt) 2021-05-25
JP2002510702A (ja) 2002-04-09
GB9807355D0 (en) 1998-06-03
HRP20000670A2 (en) 2000-12-31
EE200000585A (et) 2002-04-15
CN1222534C (zh) 2005-10-12
ZA200005197B (en) 2001-09-27
KR20010074473A (ko) 2001-08-04
MA26617A1 (fr) 2004-12-20
AR014973A1 (es) 2001-04-11
IL138559A (en) 2006-12-31
SK14822000A3 (sk) 2001-07-10
EG24597A (en) 2009-12-14
AU3703899A (en) 1999-10-25
YU58600A (sh) 2003-04-30
CA2327495A1 (en) 1999-10-14
NZ507012A (en) 2003-06-30
EE04121B1 (et) 2003-08-15
EP1070078B1 (en) 2003-01-22
DE69905025D1 (de) 2003-02-27
HUP0101549A2 (hu) 2001-10-28
WO1999051617A2 (en) 1999-10-14
IL138559A0 (en) 2001-10-31
NO316896B1 (no) 2004-06-14
ATE231517T1 (de) 2003-02-15
PL194752B1 (pl) 2007-07-31
CO5011057A1 (es) 2001-02-28
BR9909471A (pt) 2000-12-19
SK283735B6 (sk) 2003-12-02
US6482939B1 (en) 2002-11-19
BG104909A (bg) 2001-06-29

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