ZA972973B - Substituted [2-(1-piperazinyl)ethoxy]methyl compounds. - Google Patents

Substituted [2-(1-piperazinyl)ethoxy]methyl compounds.

Info

Publication number
ZA972973B
ZA972973B ZA9702973A ZA972973A ZA972973B ZA 972973 B ZA972973 B ZA 972973B ZA 9702973 A ZA9702973 A ZA 9702973A ZA 972973 A ZA972973 A ZA 972973A ZA 972973 B ZA972973 B ZA 972973B
Authority
ZA
South Africa
Prior art keywords
piperazinyl
ethoxy
substituted
methyl compounds
methyl
Prior art date
Application number
ZA9702973A
Other languages
English (en)
Inventor
Guy Duchene
Michel Deleers
Guy Bodson
Genevieve Motte
Francoise Lurquin
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of ZA972973B publication Critical patent/ZA972973B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9702973A 1996-04-10 1997-04-08 Substituted [2-(1-piperazinyl)ethoxy]methyl compounds. ZA972973B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE9600310A BE1010094A3 (fr) 1996-04-10 1996-04-10 Nouveaux [2-(1-piperazinyl)ethoxy] methyle substitues.

Publications (1)

Publication Number Publication Date
ZA972973B true ZA972973B (en) 1997-11-03

Family

ID=3889663

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9702973A ZA972973B (en) 1996-04-10 1997-04-08 Substituted [2-(1-piperazinyl)ethoxy]methyl compounds.

Country Status (26)

Country Link
US (2) US6140501A (hu)
EP (1) EP0927173B1 (hu)
JP (1) JP2000508634A (hu)
CN (1) CN1072661C (hu)
AR (1) AR006761A1 (hu)
AT (1) ATE219067T1 (hu)
AU (1) AU710835B2 (hu)
BE (1) BE1010094A3 (hu)
BR (1) BR9708763A (hu)
CZ (1) CZ295068B6 (hu)
DE (1) DE69713352T2 (hu)
DK (1) DK0927173T3 (hu)
EA (1) EA000831B1 (hu)
ES (1) ES2177965T3 (hu)
HK (1) HK1018779A1 (hu)
HU (1) HU225478B1 (hu)
IN (1) IN186873B (hu)
MY (1) MY118237A (hu)
NO (1) NO311615B1 (hu)
NZ (1) NZ332057A (hu)
PL (1) PL188819B1 (hu)
PT (1) PT927173E (hu)
RS (1) RS49574B (hu)
TR (1) TR199802025T2 (hu)
WO (1) WO1997037982A1 (hu)
ZA (1) ZA972973B (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0919550A1 (en) * 1997-11-26 1999-06-02 Ucb, S.A. Pseudopolymorphic forms of 2-2-4-bis(4-fluorophenyl)methyl-1-piperazinyl-ethoxy acetic acid dihydrochloride
IL124195A (en) * 1998-04-23 2000-08-31 Chemagis Ltd Process for the preparation of esters of 2-¬4-¬4-chlorophenyl¾phenylmethyl¾-1-piperazinyl¬ethoxy¾acetic acid
JP4763954B2 (ja) * 1999-11-30 2011-08-31 エギシュ ヂョヂセルヂャール ニルヴァーノサン ミケデ レースヴェーニタールササーグ ｛２−［４−（α−フェニル−ｐ−クロロベンジル）ピペラジン−１−イル］エトキシ｝酢酸の製法及びそのための新規な中間体
US6977301B1 (en) 2001-05-29 2005-12-20 Ucb, S.A. Process for preparing (S) and (R)—2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide
US7199241B1 (en) 2001-05-29 2007-04-03 Ucb, S.A. Process for preparing (S) and (R)-2-[4-(4-chlorobenzhydryl)piperazin-1-yl]-ethoxyacetamide
US6838052B2 (en) 2001-06-29 2005-01-04 Symyx Technologies, Inc. In-situ injection and materials screening device
WO2003009849A1 (en) * 2001-07-26 2003-02-06 Ucb, S.A. Process for the preparation of 2-(2-(4-(bis(4-fluorophenyl)methyl)-piperazin-1-yl)ethoxy)acetic acid derivatives or corresponding salt forms thereof and intermediates therefor
US7160513B2 (en) 2002-12-20 2007-01-09 Symyx Technologies, Inc. Batch reactor with injection system
US20050020608A1 (en) * 2003-03-25 2005-01-27 Dr. Reddy's Laboratories Limited Crystalline cetirizine monohydrochloride
US20040266787A1 (en) * 2003-03-25 2004-12-30 Dr. Reddy's Laboratories Limited Novel amorphous form of [2-[4-[(4-chlorophenyl)-phenyl methyl]-1-piperazinyl]ethoxy]acetic acid and process for the preparation thereof
AU2003228011A1 (en) * 2003-05-21 2004-12-13 Wockhardt Limited 2-(2-(4-((4-chlorophenyl) phenylmethyl)-1-piperazinyl)ethoxy)acetic acid monohydrochloride as anti-allergenic compound and process for its production
KR100503443B1 (ko) * 2004-02-02 2005-07-22 한림제약(주) 광학적으로 활성인 세티리진 또는 그의 염의 제조방법
WO2006050909A1 (en) * 2004-11-10 2006-05-18 Ucb Farchim Sa Novel forms of efletirizine dihydrochloride, processes for making them and pharmaceutical compositions including them
DE602007001620D1 (de) * 2006-04-10 2009-09-03 Ranbaxy Lab Ltd Verbesserter Herstellungsprozess für Aripipirazol
US20110172425A1 (en) * 2008-09-17 2011-07-14 Calyx Chemicals And Pharmaceuticals Pvt. Ltd. Novel water based process for the preparation of substituted diphenylmethyl piperazines
KR101418404B1 (ko) 2012-01-06 2014-07-10 한미약품 주식회사 레보세티리진 또는 이의 약학적으로 허용가능한 염 및 몬테루카스트 또는 이의 약학적으로 허용가능한 염을 함유하는 안정한 경구투여용 약학 제제
KR102226833B1 (ko) 2013-06-28 2021-03-12 한미약품 주식회사 레보세티리진 및 몬테루카스트를 포함하는 안정성이 개선된 복합 과립 제형

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH505116A (it) * 1966-11-21 1971-03-31 Crc Ricerca Chim Metodo per l'ottenimento di derivati della piperazina
GB1184395A (en) * 1967-03-08 1970-03-18 Egyt Gyogyszervegyeszeti Gyar Substituted Piperazine Derivatives
NO155805C (no) * 1981-02-06 1987-06-10 Ucb Sa Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-(4-(difenylmethyl)-1-piperazinyl)-eddiksyrer og deres amider og ikke-toksiske salter.
GB8827391D0 (en) * 1988-11-23 1988-12-29 Ucb Sa Process for preparation of 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-pipera-zinyl)ethoxy)-acetic acid & its dihydrochloride
GB8827390D0 (en) * 1988-11-23 1988-12-29 Ucb Sa Process for preparation of 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-pipera-zinyl)ethoxy)-acetic acid & its dihydrochloride

Also Published As

Publication number Publication date
HUP9901804A3 (en) 2000-06-28
ES2177965T3 (es) 2002-12-16
BE1010094A3 (fr) 1997-12-02
US6140501A (en) 2000-10-31
NZ332057A (en) 2000-03-27
EP0927173B1 (fr) 2002-06-12
EP0927173A1 (fr) 1999-07-07
US6255487B1 (en) 2001-07-03
IN186873B (hu) 2001-12-01
HU225478B1 (en) 2006-12-28
CN1072661C (zh) 2001-10-10
RS49574B (sr) 2007-04-10
MY118237A (en) 2004-09-30
PL329307A1 (en) 1999-03-15
HUP9901804A2 (hu) 1999-09-28
AU710835B2 (en) 1999-09-30
NO311615B1 (no) 2001-12-17
WO1997037982A1 (fr) 1997-10-16
YU44198A (sh) 1999-07-28
BR9708763A (pt) 1999-08-03
EA000831B1 (ru) 2000-04-24
DE69713352T2 (de) 2003-02-20
HK1018779A1 (en) 2000-01-07
PT927173E (pt) 2002-11-29
DK0927173T3 (da) 2002-09-16
CZ295068B6 (cs) 2005-05-18
NO984738L (no) 1998-12-08
PL188819B1 (pl) 2005-04-29
CN1215395A (zh) 1999-04-28
ATE219067T1 (de) 2002-06-15
AU2281897A (en) 1997-10-29
NO984738D0 (no) 1998-10-09
EA199800879A1 (ru) 1999-02-25
TR199802025T2 (xx) 1999-01-18
AR006761A1 (es) 1999-09-29
JP2000508634A (ja) 2000-07-11
DE69713352D1 (en) 2002-07-18
CZ315198A3 (cs) 1999-03-17

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