ZA972905B - Novel spiro[2H-1-benzopyran-2,4'-piperidine]-4(3H)-one derivatives, acid addition salts thereof and pharmaceutical compositions containing them. - Google Patents

Novel spiro[2H-1-benzopyran-2,4'-piperidine]-4(3H)-one derivatives, acid addition salts thereof and pharmaceutical compositions containing them.

Info

Publication number
ZA972905B
ZA972905B ZA9702905A ZA972905A ZA972905B ZA 972905 B ZA972905 B ZA 972905B ZA 9702905 A ZA9702905 A ZA 9702905A ZA 972905 A ZA972905 A ZA 972905A ZA 972905 B ZA972905 B ZA 972905B
Authority
ZA
South Africa
Prior art keywords
benzopyran
piperidine
derivatives
pharmaceutical compositions
acid addition
Prior art date
Application number
ZA9702905A
Other languages
English (en)
Inventor
Kalman Harsanyi
Istvan Szabadkai
Istvan Borza
Egon Karpati
Bela Kiss
Margit Pellionisz-Nee-Paroczai
Sandor Farkas
Csilla Horvath
Katalin Csomor
Erzsebet Lapis
Istvan Laszlovszky
Sandor Szabo
Agnes Kis-Varga-Nee-Zele
Judit Laszy
Aniko Gere
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ZA972905B publication Critical patent/ZA972905B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA9702905A 1996-04-10 1997-04-04 Novel spiro[2H-1-benzopyran-2,4'-piperidine]-4(3H)-one derivatives, acid addition salts thereof and pharmaceutical compositions containing them. ZA972905B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9600928A HUP9600928A3 (en) 1996-04-10 1996-04-10 Use of spiro[2h-1-benzopyran-2,4'-piperidin]-4(3h)-one derivatives for the preparation of pharmaceutical compositions treating dementia, novel derivatives and process for their preparation

Publications (1)

Publication Number Publication Date
ZA972905B true ZA972905B (en) 1997-11-03

Family

ID=89993875

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9702905A ZA972905B (en) 1996-04-10 1997-04-04 Novel spiro[2H-1-benzopyran-2,4'-piperidine]-4(3H)-one derivatives, acid addition salts thereof and pharmaceutical compositions containing them.

Country Status (25)

Country Link
US (1) US6140336A (xx)
EP (1) EP0863904A2 (xx)
JP (1) JP3048068B2 (xx)
KR (1) KR19990022807A (xx)
AU (1) AU715104B2 (xx)
BG (1) BG102171A (xx)
CA (1) CA2224212A1 (xx)
CZ (1) CZ7698A3 (xx)
EE (1) EE9700334A (xx)
FI (1) FI974470A (xx)
HU (1) HUP9600928A3 (xx)
ID (1) ID16582A (xx)
IL (1) IL122542A (xx)
IS (1) IS4632A (xx)
LT (1) LT4417B (xx)
LV (1) LV12017B (xx)
MD (1) MD1837B2 (xx)
NO (1) NO975781L (xx)
NZ (1) NZ329359A (xx)
PL (1) PL327412A1 (xx)
SI (1) SI9720006A (xx)
SK (1) SK178697A3 (xx)
TR (1) TR199701627T1 (xx)
WO (1) WO1997037630A2 (xx)
ZA (1) ZA972905B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI243173B (en) 1999-11-17 2005-11-11 Akzo Nobel Nv Spiro[2H-1-benzopyran-2,4'-piperidine] derivatives
EP1716147B1 (en) * 2004-01-08 2007-11-14 F.Hoffmann-La Roche Ag Diaza-spiropiperidine derivatives as inhibitors of glycine transporter 1 and glycine transporter 2
WO2007088462A1 (en) * 2006-02-01 2007-08-09 Pfizer Products Inc. Spirochromane antagonists of the h-3 receptor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2745306A1 (de) * 1977-10-07 1979-04-19 Bayer Ag Insektizide mittel
JPS55143980A (en) * 1979-04-27 1980-11-10 Dai Ichi Seiyaku Co Ltd Anti-allergic preparation
IL96507A0 (en) * 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
BG102171A (en) 1998-08-31
CA2224212A1 (en) 1997-10-16
NZ329359A (en) 1999-05-28
PL327412A1 (en) 1998-12-07
SK178697A3 (en) 1998-06-03
WO1997037630A3 (en) 1998-01-29
EP0863904A2 (en) 1998-09-16
HU9600928D0 (en) 1996-05-28
ID16582A (id) 1997-10-16
LT4417B (lt) 1998-12-28
IL122542A (en) 2001-01-11
HUP9600928A3 (en) 1999-03-29
LV12017B (en) 1998-08-20
IL122542A0 (en) 1998-06-15
SI9720006A (sl) 1998-12-31
HUP9600928A2 (hu) 1998-05-28
LV12017A (lv) 1998-04-20
FI974470A0 (fi) 1997-12-09
AU715104B2 (en) 2000-01-13
LT97193A (en) 1998-07-27
IS4632A (is) 1997-12-09
WO1997037630A2 (en) 1997-10-16
EE9700334A (et) 1998-06-15
TR199701627T1 (xx) 1999-05-21
US6140336A (en) 2000-10-31
FI974470A (fi) 1998-01-16
JP3048068B2 (ja) 2000-06-05
MD980029A (en) 1999-08-30
MX9710029A (es) 1998-09-30
AU2173497A (en) 1997-10-29
NO975781L (no) 1998-02-10
MD1837B2 (ro) 2002-01-31
NO975781D0 (no) 1997-12-09
CZ7698A3 (cs) 1998-04-15
KR19990022807A (ko) 1999-03-25
JPH10510850A (ja) 1998-10-20

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