ZA969490B - Compounds useful for the inhibition of the replication of hiv-1 and hiv-1 mutants - Google Patents

Compounds useful for the inhibition of the replication of hiv-1 and hiv-1 mutants

Info

Publication number
ZA969490B
ZA969490B ZA969490A ZA969490A ZA969490B ZA 969490 B ZA969490 B ZA 969490B ZA 969490 A ZA969490 A ZA 969490A ZA 969490 A ZA969490 A ZA 969490A ZA 969490 B ZA969490 B ZA 969490B
Authority
ZA
South Africa
Prior art keywords
hiv
mutants
replication
inhibition
compounds useful
Prior art date
Application number
ZA969490A
Other languages
English (en)
Inventor
Walter Gerhard Brouwer
Ewa Maria Osika
Benjamin James Pierce
Original Assignee
Uniroyal Chem Co Inc
Uniroyal Chemical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniroyal Chem Co Inc, Uniroyal Chemical Ltd filed Critical Uniroyal Chem Co Inc
Publication of ZA969490B publication Critical patent/ZA969490B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA969490A 1995-11-30 1996-11-12 Compounds useful for the inhibition of the replication of hiv-1 and hiv-1 mutants ZA969490B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/565,493 US5696151A (en) 1995-11-30 1995-11-30 Compounds useful for the inhibition of the replication of HIV-1 and HIV-1 mutants

Publications (1)

Publication Number Publication Date
ZA969490B true ZA969490B (en) 1997-06-02

Family

ID=24258853

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA969490A ZA969490B (en) 1995-11-30 1996-11-12 Compounds useful for the inhibition of the replication of hiv-1 and hiv-1 mutants

Country Status (21)

Country Link
US (1) US5696151A (xx)
EP (1) EP0874839B1 (xx)
JP (1) JP3027771B2 (xx)
KR (1) KR100505841B1 (xx)
CN (1) CN1098847C (xx)
AP (1) AP902A (xx)
AT (1) ATE224382T1 (xx)
AU (1) AU704086B2 (xx)
BR (1) BR9611838A (xx)
CA (1) CA2237194C (xx)
DE (1) DE69623819T2 (xx)
DK (1) DK0874839T3 (xx)
ES (1) ES2183986T3 (xx)
HK (1) HK1016601A1 (xx)
HU (1) HU223660B1 (xx)
NZ (1) NZ324118A (xx)
OA (1) OA10864A (xx)
PT (1) PT874839E (xx)
TW (1) TW448169B (xx)
WO (1) WO1997019940A1 (xx)
ZA (1) ZA969490B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143780A (en) * 1999-09-17 2000-11-07 Uniroyal Chemical Company, Inc. N-arylmethylthioanilide compounds useful for the inhibition of the replication of HIV
US6017947A (en) * 1999-09-17 2000-01-25 Brouwer; Walter Gerhard Heterocyclic carbodithioperoxyimidic compounds useful for the inhibition of the replication of HIV
US6498254B1 (en) * 2001-10-29 2002-12-24 Uniroyal Chemical Company, Inc. Antiretroviral compounds and compositions
US7064139B2 (en) * 2001-10-29 2006-06-20 Uniroyal Chemical Company, Inc. Method for treating retroviral infections
DE102008015032A1 (de) 2008-03-17 2009-09-24 Aicuris Gmbh & Co. Kg Substituierte Pyrazolamide und ihre Verwendung
DE102008015033A1 (de) 2008-03-17 2009-09-24 Aicuris Gmbh & Co. Kg Substituierte (Pyrazolyl-carbonyl)imidazolidinone und ihre Verwendung
DE102008062863A1 (de) 2008-12-17 2010-06-24 Aicuris Gmbh & Co. Kg Substituierte (Thiophenyl-carbonyl)imidazolidinone und ihre Verwendung
DE102008062878A1 (de) * 2008-12-17 2010-06-24 Aicuris Gmbh & Co. Kg Substituierte Furancarboxamide und ihre Verwendung
CN101987842A (zh) * 2009-07-31 2011-03-23 上海开拓者医药发展有限公司 一种2-甲基噻吩衍生物的制备方法
CN106715401A (zh) 2014-07-24 2017-05-24 拜耳作物科学股份公司 杀真菌的吡唑衍生物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268389A (en) * 1989-10-16 1993-12-07 Uniroyal Chemical Company, Inc. Thiocarboxylate ester compounds compositions containing the same
US5968910A (en) * 1994-11-30 1999-10-19 Jan M. R. Balzarini Compositions containing two or three inhibitors of different HIV reverse transcriptases

Also Published As

Publication number Publication date
JP3027771B2 (ja) 2000-04-04
EP0874839B1 (en) 2002-09-18
OA10864A (en) 2003-02-18
KR100505841B1 (ko) 2005-12-14
DE69623819D1 (de) 2002-10-24
TW448169B (en) 2001-08-01
PT874839E (pt) 2003-02-28
KR19990071682A (ko) 1999-09-27
CA2237194C (en) 2006-06-13
ES2183986T3 (es) 2003-04-01
DE69623819T2 (de) 2003-05-28
WO1997019940A1 (en) 1997-06-05
JPH11504657A (ja) 1999-04-27
US5696151A (en) 1997-12-09
AU1119997A (en) 1997-06-19
AP902A (en) 2000-11-23
AP9801245A0 (en) 1998-06-30
CN1098847C (zh) 2003-01-15
EP0874839A1 (en) 1998-11-04
ATE224382T1 (de) 2002-10-15
CA2237194A1 (en) 1997-06-05
HU223660B1 (hu) 2004-11-29
HK1016601A1 (en) 1999-11-05
DK0874839T3 (da) 2003-01-27
AU704086B2 (en) 1999-04-15
BR9611838A (pt) 1999-03-09
HUP9901990A2 (en) 2000-07-28
CN1203596A (zh) 1998-12-30
HUP9901990A3 (en) 2000-08-28
NZ324118A (en) 1999-02-25

Similar Documents

Publication Publication Date Title
AU6594796A (en) Photoactivatable compounds for the prevention of intimal hyperplasia and other diseases
PL323904A1 (en) C-4' modified inhibitors of andenosinic kinase
PL322277A1 (en) Derivatives of pyrazol-4-ylobenzoyl
ZA962879B (en) A pharmaceutical composition for inhibiting the growth of viruses and cancers
PL324451A1 (en) Derivatives of diphenylmethylenepiperidine
AU1448092A (en) Splitter and method of forming it
EP0761718A3 (de) Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden
AU673375B2 (en) Process for the duplication or construction of a copy of a denture and the product thereby obtained
AU4965797A (en) Process for producing nucleoside 5'-triphosphates and application of the same
AP9801245A0 (en) Compounds useful for the inhibition of the replication of hiv-1 and hiv-1 mutants
EP0722949A3 (en) Process for the preparation of cyclopentadienyl compounds and compounds produced by the process
SI0877738T1 (en) Process for the preparation of phenylimidazolidine derivatives
AU4248297A (en) Inhibition of viral replication
EP0761721A3 (de) Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden
HUP9903481A3 (en) Process for the preparation of 1-aryl-1-cyanocyclobutane derivatives
AU6962894A (en) Compositions and methods for inhibiting replication of human immunodeficiency virus-1
EP0833668A4 (en) INHIBITATION OF THE HEPATITIS B VIRUS REPLICATION
AU6378598A (en) Method for inhibition of virus replication
EP0688225A4 (en) METHODS AND COMPOSITIONS FOR INHIBITING SUPPLEMENT ACTIVATION
EP0761719A3 (de) Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden
EP0761720A3 (de) Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden
AU6658796A (en) Process for the modification of toxic and/or off-flavoured compounds
EP0823256A4 (en) PREVENTIVE OR THERAPEUTIC MEDICINE, OR BOTH, FOR ISCHEMIC CONDITIONS
IL117968A (en) Process for the preparation of streptogramins and some new compounds of this class
AU6469496A (en) Virus replication inhibitor