ZA968790B - Combination antiemetic therapy using NK-1 receptor antagonists. - Google Patents

Combination antiemetic therapy using NK-1 receptor antagonists.

Info

Publication number
ZA968790B
ZA968790B ZA9608790A ZA968790A ZA968790B ZA 968790 B ZA968790 B ZA 968790B ZA 9608790 A ZA9608790 A ZA 9608790A ZA 968790 A ZA968790 A ZA 968790A ZA 968790 B ZA968790 B ZA 968790B
Authority
ZA
South Africa
Prior art keywords
combination
receptor antagonists
antiemetic therapy
antiemetic
therapy
Prior art date
Application number
ZA9608790A
Other languages
English (en)
Inventor
Susan F Gonsalves
Sandra L Silberman
John W Watson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA968790B publication Critical patent/ZA968790B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
ZA9608790A 1995-10-20 1996-10-18 Combination antiemetic therapy using NK-1 receptor antagonists. ZA968790B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US572895P 1995-10-20 1995-10-20

Publications (1)

Publication Number Publication Date
ZA968790B true ZA968790B (en) 1998-04-20

Family

ID=21717419

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9608790A ZA968790B (en) 1995-10-20 1996-10-18 Combination antiemetic therapy using NK-1 receptor antagonists.

Country Status (9)

Country Link
EP (1) EP0769300A3 (fr)
JP (1) JPH09110721A (fr)
CN (1) CN1151893A (fr)
AU (1) AU700841B2 (fr)
CA (1) CA2188227C (fr)
IL (1) IL119418A (fr)
NZ (1) NZ299606A (fr)
TW (1) TW458774B (fr)
ZA (1) ZA968790B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0533280B2 (fr) 1991-09-20 2004-12-01 Glaxo Group Limited Nouvelle indication médicale pour les antagonistes des tachykinines

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0360390A1 (fr) 1988-07-25 1990-03-28 Glaxo Group Limited Dérivés de spirolactames
WO1990005525A1 (fr) 1988-11-23 1990-05-31 Pfizer Inc. Derives de quinuclidine en tant qu'antagonsites de substance p
IE903957A1 (en) 1989-11-06 1991-05-08 Sanofi Sa Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present
US5232929A (en) 1990-11-28 1993-08-03 Pfizer Inc. 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
CZ387492A3 (en) 1990-09-28 1994-02-16 Pfizer Analogs of non-aromatic hetero cycles containing nitrogen with a condensed ring, process of their preparation and use
WO1992012151A1 (fr) 1991-01-10 1992-07-23 Pfizer Inc. Sels de n-alkyle quinuclidinium utilises comme antagonistes de substance p
EP0499313B1 (fr) 1991-02-11 1997-06-11 MERCK SHARP & DOHME LTD. Composés azabicycliques, compositions pharmaceutiques les contenant et leur utilisation thérapeutique
EP0573522B1 (fr) 1991-03-01 1994-12-14 Pfizer Inc. Derives de 1-azabicyclo[3.2.2]nonan-3-amine
UA26401C2 (uk) 1991-05-22 1999-08-30 Пфайзер Інк. Заміщеhі 3-аміhохіhуклідиhи
US5292726A (en) 1991-05-22 1994-03-08 Merck & Co., Inc. N,N-diacylpiperazines
AU657552B2 (en) 1991-05-31 1995-03-16 Pfizer Inc. Quinuclidine as substance P antagonists
JPH07110850B2 (ja) 1991-06-20 1995-11-29 フアイザー・インコーポレイテツド 窒素含有複素環化合物のフルオロアルコキシベンジルアミノ誘導体
TW202432B (fr) 1991-06-21 1993-03-21 Pfizer
US5288730A (en) 1991-06-24 1994-02-22 Merck Sharp & Dohme Limited Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
CA2110513A1 (fr) 1991-07-05 1993-01-21 Christopher J. Swain Composes aromatiques, compositions pharmaceutiques contenant lesdits composes et leur utilisation a des fins therapeutiques
EP0593559A1 (fr) 1991-07-05 1994-04-27 MERCK SHARP & DOHME LTD. Composes aromatiques, compositions pharmaceutiques les contenant et leur utilisation therapeutique
US5495047A (en) 1991-07-10 1996-02-27 Merck, Sharp & Dohme (Ltd.) Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy
EP0593615B1 (fr) 1991-07-10 1996-01-31 MERCK SHARP & DOHME LTD. Composes aromatiques, compositions les contenant et leurs utilisations therapeutiques
DE69210029T2 (de) 1991-08-20 1997-01-09 Merck Sharp & Dohme Azacyclische verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
EP0533280B2 (fr) * 1991-09-20 2004-12-01 Glaxo Group Limited Nouvelle indication médicale pour les antagonistes des tachykinines
HU9400728D0 (en) 1991-09-26 1994-06-28 Pfizer Fused tricyclic nitrogen containing heterocycles as substance p receptor antagonists
JP2614408B2 (ja) 1991-11-12 1997-05-28 ファイザー・インコーポレーテッド サブスタンスｐ受容体アンタゴニストとしての非環式エチレンジアミン誘導体
DE4143345B4 (de) 1991-12-04 2007-03-22 Rieter Ingolstadt Spinnereimaschinenbau Ag Drehteller einer Spinnereivorbereitungsmaschine
GB9201179D0 (en) 1992-01-21 1992-03-11 Glaxo Group Ltd Chemical compounds
JP2656702B2 (ja) 1992-03-23 1997-09-24 ファイザー製薬株式会社 ペプチド性キヌクリジン
JP2909214B2 (ja) 1992-08-19 1999-06-23 フアイザー・インコーポレイテツド 置換ベンジルアミノ窒素含有非芳香族複素環化合物
JP2656699B2 (ja) 1992-10-21 1997-09-24 ファイザー製薬株式会社 置換ベンジルアミノキヌクリジン
ES2147759T3 (es) 1992-12-10 2000-10-01 Pfizer Heterociclos no aromaticos sustituidos con aminometileno y uso como antagonistas de la sustancia p.
ATE166650T1 (de) 1993-03-04 1998-06-15 Pfizer Spiroazacyclischderivate als substanz p antagonisten
GB9305718D0 (en) * 1993-03-19 1993-05-05 Glaxo Group Ltd Medicaments
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
GB9315808D0 (en) 1993-07-30 1993-09-15 Merck Sharp & Dohme Therapeutic agents
GB9317987D0 (en) * 1993-08-26 1993-10-13 Glaxo Group Ltd Chemical compounds
IL111002A (en) * 1993-09-22 1998-09-24 Glaxo Group Ltd History of piperidine, their preparation and the pharmaceutical preparations containing them
EP0739336B1 (fr) 1994-01-13 1998-08-26 MERCK SHARP & DOHME LTD. Antagonistes de tachykinine azacycliques a double substitution gem
CA2181376A1 (fr) 1994-01-28 1995-08-03 Malcolm Maccoss Agents therapeutiques azacycliques avec substitution par un groupe aralkyamino
PE45195A1 (es) 1994-03-03 1996-01-17 Boehringer Ingelheim Kg Derivado de aminoacido, procedimiento para su preparacion y composicion farmaceutica que lo contiene
GB9525296D0 (en) * 1995-12-11 1996-02-07 Merck Sharp & Dohme Therapeutic agents

Also Published As

Publication number Publication date
MX9605030A (es) 1997-09-30
CN1151893A (zh) 1997-06-18
IL119418A (en) 2001-07-24
AU7027996A (en) 1997-05-15
EP0769300A3 (fr) 1999-11-24
EP0769300A2 (fr) 1997-04-23
CA2188227A1 (fr) 1997-04-21
IL119418A0 (en) 1997-01-10
NZ299606A (en) 2000-07-28
CA2188227C (fr) 2000-08-08
TW458774B (en) 2001-10-11
AU700841B2 (en) 1999-01-14
JPH09110721A (ja) 1997-04-28

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