ZA967800B - Heteroaryllsubstituted acryloylguanidine derivatives and pharmaceutical compositions comprising them - Google Patents
Heteroaryllsubstituted acryloylguanidine derivatives and pharmaceutical compositions comprising themInfo
- Publication number
- ZA967800B ZA967800B ZA967800A ZA967800A ZA967800B ZA 967800 B ZA967800 B ZA 967800B ZA 967800 A ZA967800 A ZA 967800A ZA 967800 A ZA967800 A ZA 967800A ZA 967800 B ZA967800 B ZA 967800B
- Authority
- ZA
- South Africa
- Prior art keywords
- heteroaryllsubstituted
- pharmaceutical compositions
- acryloylguanidine
- derivatives
- acryloylguanidine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP24171695 | 1995-09-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA967800B true ZA967800B (en) | 1997-04-03 |
Family
ID=17078479
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA967800A ZA967800B (en) | 1995-09-20 | 1996-09-16 | Heteroaryllsubstituted acryloylguanidine derivatives and pharmaceutical compositions comprising them |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0861831A4 (zh) |
KR (1) | KR19990063589A (zh) |
CN (1) | CN1196721A (zh) |
AU (1) | AU702092B2 (zh) |
BR (1) | BR9610530A (zh) |
CA (1) | CA2232497A1 (zh) |
CZ (1) | CZ84098A3 (zh) |
HU (1) | HUP9901336A3 (zh) |
NO (1) | NO981241L (zh) |
PL (1) | PL326033A1 (zh) |
SK (1) | SK35198A3 (zh) |
WO (1) | WO1997011055A1 (zh) |
ZA (1) | ZA967800B (zh) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0854721B1 (en) * | 1995-08-02 | 2001-10-24 | Smithkline Beecham Corporation | Endothelin receptor antagonists |
JP3652708B2 (ja) * | 1997-03-06 | 2005-05-25 | トーアエイヨー株式会社 | シクロアルカ[b]ピリジン−3−カルボニルグアニジン誘導体、その製造法およびそれを含有する医薬品 |
EP1206464A4 (en) * | 1999-08-23 | 2002-12-18 | Smithkline Beecham Corp | FATTY ACID SYNTHASE INHIBITORS |
WO2002051441A1 (fr) * | 2000-12-26 | 2002-07-04 | Sankyo Company, Limited | Compositions medicinales contenant un diuretique et un agent renforçant la resistance a l'insuline |
PE20060299A1 (es) | 2004-06-16 | 2006-05-18 | Wyeth Corp | DIFENILIMIDAZOPIRIMIDINA E -IMIDAZOL AMINAS COMO INHIBIDORES DE ß-SECRETASA |
RU2006142552A (ru) | 2004-06-16 | 2008-07-27 | Вайет (Us) | Производные амино-5,5-дифенилимидазолона как ингибиторы b-секретазы |
JP2008526966A (ja) | 2005-01-14 | 2008-07-24 | ワイス | β−セクレターゼの阻害のためのアミノ−イミダゾロン |
AU2006211159A1 (en) | 2005-02-01 | 2006-08-10 | Wyeth | Amino-pyridines as inhibitors of beta-secretase |
WO2006088694A1 (en) | 2005-02-14 | 2006-08-24 | Wyeth | SUBSTITUTED THIENYL AND FURYL ACYLGUANIDINES AS β-SECRETASE MODULATORS |
CA2597594A1 (en) | 2005-02-14 | 2006-08-24 | Wyeth | Azolylacylguanidines as beta-secretase inhibitors |
CN101213183A (zh) | 2005-06-30 | 2008-07-02 | 惠氏公司 | 氨基-5-(6元)杂芳基咪唑酮化合物和在β-分泌酶调节中的用途 |
TW200738683A (en) | 2005-06-30 | 2007-10-16 | Wyeth Corp | Amino-5-(5-membered)heteroarylimidazolone compounds and the use thereof for β-secretase modulation |
RU2008106936A (ru) | 2005-09-26 | 2009-11-10 | Вайет (Us) | Соединения амино-5-[4-(дифторметокси)фенил]-5-фенилимидазолона для ингибирования бета-секретазы |
WO2007100536A1 (en) | 2006-02-24 | 2007-09-07 | Wyeth | DIHYDROSPIRO[DIBENZO[A,D][7]ANNULENE-5,4'-IMIDAZOL] COMPOUNDS FOR THE INHIBITION OF β-SECRETASE |
US7700606B2 (en) | 2006-08-17 | 2010-04-20 | Wyeth Llc | Imidazole amines as inhibitors of β-secretase |
PE20090617A1 (es) | 2007-03-23 | 2009-05-08 | Wyeth Corp | Compuestos amino-5-[-4-(difluorometoxi)fenil]-5-fenilimidazolona para la inhibicion de -secretasa |
WO2018065288A1 (de) | 2016-10-07 | 2018-04-12 | Bayer Cropscience Aktiengesellschaft | 2-[2-phenyl-1-(sulfonylmethyl)vinyl]-imidazo[4,5-b]pyridin-derivate und verwandte verbindungen als schädlingsbekämpfungsmittel im pflanzenschutz |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3929582A1 (de) | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
ATE139526T1 (de) * | 1992-02-15 | 1996-07-15 | Hoechst Ag | 3,5-substituierte benzoylguanidine, mit antiarrythmischer wirkung und inhibierender wirkung auf die proliferationen von zellen |
JP3162572B2 (ja) * | 1993-04-28 | 2001-05-08 | 住友製薬株式会社 | インドロイルグアニジン誘導体 |
US5401758A (en) * | 1993-10-07 | 1995-03-28 | Bristol-Myers Squibb Company | Pyridinyl cyanoguanidine compounds |
DE4430861A1 (de) * | 1994-08-31 | 1996-03-07 | Merck Patent Gmbh | Heterocyclyl-benzoylguanidine |
JPH0959245A (ja) * | 1995-08-25 | 1997-03-04 | Yamanouchi Pharmaceut Co Ltd | N−(2−プロペノイル)グアニジン誘導体 |
-
1996
- 1996-09-16 ZA ZA967800A patent/ZA967800B/xx unknown
- 1996-09-19 EP EP96931252A patent/EP0861831A4/en not_active Withdrawn
- 1996-09-19 SK SK351-98A patent/SK35198A3/sk unknown
- 1996-09-19 PL PL96326033A patent/PL326033A1/xx unknown
- 1996-09-19 AU AU70007/96A patent/AU702092B2/en not_active Ceased
- 1996-09-19 HU HU9901336A patent/HUP9901336A3/hu unknown
- 1996-09-19 CN CN96196999A patent/CN1196721A/zh active Pending
- 1996-09-19 CA CA002232497A patent/CA2232497A1/en not_active Abandoned
- 1996-09-19 WO PCT/JP1996/002696 patent/WO1997011055A1/ja not_active Application Discontinuation
- 1996-09-19 CZ CZ98840A patent/CZ84098A3/cs unknown
- 1996-09-19 KR KR1019980702028A patent/KR19990063589A/ko not_active Application Discontinuation
- 1996-09-19 BR BR9610530A patent/BR9610530A/pt not_active Application Discontinuation
-
1998
- 1998-03-19 NO NO981241A patent/NO981241L/no unknown
Also Published As
Publication number | Publication date |
---|---|
HUP9901336A3 (en) | 2000-02-28 |
EP0861831A4 (en) | 1998-11-11 |
CA2232497A1 (en) | 1997-03-27 |
KR19990063589A (ko) | 1999-07-26 |
AU7000796A (en) | 1997-04-09 |
WO1997011055A1 (fr) | 1997-03-27 |
AU702092B2 (en) | 1999-02-11 |
CZ84098A3 (cs) | 1998-09-16 |
HUP9901336A2 (hu) | 1999-08-30 |
NO981241D0 (no) | 1998-03-19 |
NO981241L (no) | 1998-05-20 |
BR9610530A (pt) | 1999-07-06 |
EP0861831A1 (en) | 1998-09-02 |
SK35198A3 (en) | 1999-06-11 |
CN1196721A (zh) | 1998-10-21 |
MX9802238A (es) | 1998-08-30 |
PL326033A1 (en) | 1998-08-17 |
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