ZA966808B - A method of determining the degree of aggregation of the βA4 peptide. - Google Patents

A method of determining the degree of aggregation of the βA4 peptide.

Info

Publication number
ZA966808B
ZA966808B ZA9606808A ZA966808A ZA966808B ZA 966808 B ZA966808 B ZA 966808B ZA 9606808 A ZA9606808 A ZA 9606808A ZA 966808 A ZA966808 A ZA 966808A ZA 966808 B ZA966808 B ZA 966808B
Authority
ZA
South Africa
Prior art keywords
aggregation
peptide
determining
degree
Prior art date
Application number
ZA9606808A
Other languages
English (en)
Inventor
Shefali Goyal
Norbert Guenther Riedel
Joseph West Paul
Sudhir Ramchandra Sahasrabudhe
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of ZA966808B publication Critical patent/ZA966808B/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
ZA9606808A 1995-08-16 1996-08-12 A method of determining the degree of aggregation of the βA4 peptide. ZA966808B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51560695A 1995-08-16 1995-08-16

Publications (1)

Publication Number Publication Date
ZA966808B true ZA966808B (en) 1997-02-19

Family

ID=24052039

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9606808A ZA966808B (en) 1995-08-16 1996-08-12 A method of determining the degree of aggregation of the βA4 peptide.

Country Status (19)

Country Link
EP (1) EP0846269B1 (zh)
JP (1) JP3042895B2 (zh)
KR (1) KR19990036439A (zh)
CN (1) CN1107230C (zh)
AR (1) AR003251A1 (zh)
AT (1) ATE250766T1 (zh)
AU (1) AU697842B2 (zh)
CA (1) CA2229187C (zh)
DE (1) DE69630131T2 (zh)
DK (1) DK0846269T3 (zh)
ES (1) ES2206586T3 (zh)
HK (1) HK1015030A1 (zh)
IL (1) IL122759A (zh)
NO (1) NO980623D0 (zh)
NZ (1) NZ313070A (zh)
PT (1) PT846269E (zh)
TW (1) TW574503B (zh)
WO (1) WO1997007403A1 (zh)
ZA (1) ZA966808B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60336848D1 (de) * 2002-09-12 2011-06-01 Univ California Immunogene und entsprechende antikörper, die spezifisch sind für häufige hochmolekulare aggregations-zwischenprodukte von amyloiden aus proteinen unterschiedlicher sequenz
EP3147668B1 (en) * 2014-05-22 2019-12-11 Shimadzu Corporation Surrogate biomarker for evaluating intracerebral amyloid beta peptide accumulation and method for analysis thereof
CN104729946A (zh) * 2014-12-18 2015-06-24 江苏大学 一种检测淀粉样多肽聚集及其聚集抑制剂评估的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816416A (en) * 1986-08-27 1989-03-28 Paul Averback Microspheric bodies for use in screening therapies for Azheimer's disease and related conditions
AU7556994A (en) * 1993-08-13 1995-03-14 Molecular Geriatrics Corporation Methods for the diagnosis of alzheimer's disease
US5744368A (en) * 1993-11-04 1998-04-28 Research Foundation Of State University Of New York Methods for the detection of soluble amyloid β-protein (βAP) or soluble transthyretin (TTR)

Also Published As

Publication number Publication date
CA2229187C (en) 2003-03-18
CN1107230C (zh) 2003-04-30
TW574503B (en) 2004-02-01
WO1997007403A1 (en) 1997-02-27
JP3042895B2 (ja) 2000-05-22
HK1015030A1 (en) 1999-10-08
KR19990036439A (ko) 1999-05-25
IL122759A0 (en) 1998-08-16
CN1193385A (zh) 1998-09-16
NZ313070A (en) 1999-01-28
EP0846269A1 (en) 1998-06-10
IL122759A (en) 2003-05-29
ATE250766T1 (de) 2003-10-15
AU697842B2 (en) 1998-10-15
AU6505296A (en) 1997-03-12
MX9801255A (es) 1998-05-31
NO980623L (no) 1998-02-13
NO980623D0 (no) 1998-02-13
DK0846269T3 (da) 2003-12-01
JPH11501398A (ja) 1999-02-02
DE69630131T2 (de) 2004-07-08
CA2229187A1 (en) 1997-02-27
ES2206586T3 (es) 2004-05-16
AR003251A1 (es) 1998-07-08
DE69630131D1 (de) 2003-10-30
PT846269E (pt) 2004-01-30
EP0846269B1 (en) 2003-09-24

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