ZA964951B - Method for the preparation of taxol and its derivatives - Google Patents

Method for the preparation of taxol and its derivatives

Info

Publication number
ZA964951B
ZA964951B ZA964951A ZA964951A ZA964951B ZA 964951 B ZA964951 B ZA 964951B ZA 964951 A ZA964951 A ZA 964951A ZA 964951 A ZA964951 A ZA 964951A ZA 964951 B ZA964951 B ZA 964951B
Authority
ZA
South Africa
Prior art keywords
formula
compound
aryl
heteroaryl
chem
Prior art date
Application number
ZA964951A
Other languages
English (en)
Inventor
Cesare Gennari
Nicola Mongelli
Ermes Vanotti
Anna Vulpetti
Original Assignee
Pharmacia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Spa filed Critical Pharmacia Spa
Publication of ZA964951B publication Critical patent/ZA964951B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA964951A 1995-06-20 1996-06-11 Method for the preparation of taxol and its derivatives ZA964951B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9512471.5A GB9512471D0 (en) 1995-06-20 1995-06-20 Method for the preparation of taxol and its derivatives

Publications (1)

Publication Number Publication Date
ZA964951B true ZA964951B (en) 1997-01-23

Family

ID=10776319

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA964951A ZA964951B (en) 1995-06-20 1996-06-11 Method for the preparation of taxol and its derivatives

Country Status (17)

Country Link
US (1) US5767282A (xx)
EP (2) EP1116718A3 (xx)
JP (1) JP3889047B2 (xx)
KR (1) KR970705552A (xx)
CN (1) CN1179955C (xx)
AT (1) ATE208381T1 (xx)
AU (1) AU712898B2 (xx)
CA (1) CA2197467C (xx)
DE (1) DE69616719T2 (xx)
ES (1) ES2168489T3 (xx)
GB (1) GB9512471D0 (xx)
HU (1) HUP9702399A3 (xx)
IL (1) IL120165A (xx)
MX (1) MX9701274A (xx)
NO (1) NO970766D0 (xx)
WO (1) WO1997000870A1 (xx)
ZA (1) ZA964951B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150537A (en) * 1997-12-12 2000-11-21 Emory University Methods for the esterification of alcohols and compounds useful therefor as potential anticancer agents
WO2000047434A1 (en) 1999-02-10 2000-08-17 Erik Zapletal Balanced suspension system
IT1308636B1 (it) * 1999-03-02 2002-01-09 Indena Spa Procedimento per la preparazione di tassani da 10-desacetilbaccatinaiii.
AU757591B2 (en) 1999-04-12 2003-02-27 Kinetic Pty Limited Active ride control for a vehicle suspension system
EP2266607A3 (en) 1999-10-01 2011-04-20 Immunogen, Inc. Immunoconjugates for treating cancer
WO2001030770A1 (en) * 1999-10-26 2001-05-03 Dong Kook Pharmaceutical Co., Ltd. Stereoselective synthesis of oxazoline derivative
PL194032B1 (pl) * 2002-12-19 2007-04-30 Agropharm Sa Sposób wytwarzania półproduktów użytecznych w syntezie paklitakselu
CN101020672B (zh) * 2006-12-28 2010-08-25 上海百灵医药科技有限公司 多烯紫杉醇的合成方法
CN101007795B (zh) * 2007-01-26 2010-08-18 浙江大学 紫杉醇及多烯紫杉醇的合成方法
CN115260130A (zh) * 2022-07-07 2022-11-01 上海卓鼎生物技术有限公司 一种10-脱乙酰基紫杉醇的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
FR2687151B1 (fr) * 1992-02-07 1994-03-25 Rhone Poulenc Rorer Sa Nouveaux derives de la baccatine iii et de la desacetyl-10 baccatine iii, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2696458B1 (fr) * 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.

Also Published As

Publication number Publication date
NO970766L (no) 1997-02-19
ATE208381T1 (de) 2001-11-15
DE69616719T2 (de) 2002-08-01
KR970705552A (ko) 1997-10-09
CA2197467A1 (en) 1997-01-09
EP0776322B1 (en) 2001-11-07
HUP9702399A3 (en) 1999-12-28
ES2168489T3 (es) 2002-06-16
JPH10505360A (ja) 1998-05-26
US5767282A (en) 1998-06-16
MX9701274A (es) 1997-05-31
WO1997000870A1 (en) 1997-01-09
IL120165A0 (en) 1997-06-10
CA2197467C (en) 2008-02-12
CN1179955C (zh) 2004-12-15
JP3889047B2 (ja) 2007-03-07
IL120165A (en) 2002-02-10
DE69616719D1 (de) 2001-12-13
CN1158126A (zh) 1997-08-27
AU712898B2 (en) 1999-11-18
EP1116718A2 (en) 2001-07-18
EP0776322A1 (en) 1997-06-04
NO970766D0 (no) 1997-02-19
EP1116718A3 (en) 2001-08-29
HUP9702399A2 (hu) 1998-07-28
AU6221596A (en) 1997-01-22
GB9512471D0 (en) 1995-08-23

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