ZA964951B - Method for the preparation of taxol and its derivatives - Google Patents

Method for the preparation of taxol and its derivatives

Info

Publication number
ZA964951B
ZA964951B ZA964951A ZA964951A ZA964951B ZA 964951 B ZA964951 B ZA 964951B ZA 964951 A ZA964951 A ZA 964951A ZA 964951 A ZA964951 A ZA 964951A ZA 964951 B ZA964951 B ZA 964951B
Authority
ZA
South Africa
Prior art keywords
formula
compound
aryl
heteroaryl
chem
Prior art date
Application number
ZA964951A
Other languages
English (en)
Inventor
Cesare Gennari
Nicola Mongelli
Ermes Vanotti
Anna Vulpetti
Original Assignee
Pharmacia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Spa filed Critical Pharmacia Spa
Publication of ZA964951B publication Critical patent/ZA964951B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
ZA964951A 1995-06-20 1996-06-11 Method for the preparation of taxol and its derivatives ZA964951B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9512471.5A GB9512471D0 (en) 1995-06-20 1995-06-20 Method for the preparation of taxol and its derivatives

Publications (1)

Publication Number Publication Date
ZA964951B true ZA964951B (en) 1997-01-23

Family

ID=10776319

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA964951A ZA964951B (en) 1995-06-20 1996-06-11 Method for the preparation of taxol and its derivatives

Country Status (17)

Country Link
US (1) US5767282A (fr)
EP (2) EP1116718A3 (fr)
JP (1) JP3889047B2 (fr)
KR (1) KR970705552A (fr)
CN (1) CN1179955C (fr)
AT (1) ATE208381T1 (fr)
AU (1) AU712898B2 (fr)
CA (1) CA2197467C (fr)
DE (1) DE69616719T2 (fr)
ES (1) ES2168489T3 (fr)
GB (1) GB9512471D0 (fr)
HU (1) HUP9702399A3 (fr)
IL (1) IL120165A (fr)
MX (1) MX9701274A (fr)
NO (1) NO970766D0 (fr)
WO (1) WO1997000870A1 (fr)
ZA (1) ZA964951B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150537A (en) * 1997-12-12 2000-11-21 Emory University Methods for the esterification of alcohols and compounds useful therefor as potential anticancer agents
WO2000047434A1 (fr) 1999-02-10 2000-08-17 Erik Zapletal Systeme de suspension equilibree
IT1308636B1 (it) * 1999-03-02 2002-01-09 Indena Spa Procedimento per la preparazione di tassani da 10-desacetilbaccatinaiii.
AU757591B2 (en) 1999-04-12 2003-02-27 Kinetic Pty Limited Active ride control for a vehicle suspension system
EP2266607A3 (fr) 1999-10-01 2011-04-20 Immunogen, Inc. Des immunoconjugués pour le traitement des cancers.
WO2001030770A1 (fr) * 1999-10-26 2001-05-03 Dong Kook Pharmaceutical Co., Ltd. Synthese stereoselective de derives oxazoline
PL194032B1 (pl) * 2002-12-19 2007-04-30 Agropharm Sa Sposób wytwarzania półproduktów użytecznych w syntezie paklitakselu
CN101020672B (zh) * 2006-12-28 2010-08-25 上海百灵医药科技有限公司 多烯紫杉醇的合成方法
CN101007795B (zh) * 2007-01-26 2010-08-18 浙江大学 紫杉醇及多烯紫杉醇的合成方法
CN115260130A (zh) * 2022-07-07 2022-11-01 上海卓鼎生物技术有限公司 一种10-脱乙酰基紫杉醇的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
FR2687151B1 (fr) * 1992-02-07 1994-03-25 Rhone Poulenc Rorer Sa Nouveaux derives de la baccatine iii et de la desacetyl-10 baccatine iii, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2696458B1 (fr) * 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.

Also Published As

Publication number Publication date
NO970766L (no) 1997-02-19
ATE208381T1 (de) 2001-11-15
DE69616719T2 (de) 2002-08-01
KR970705552A (ko) 1997-10-09
CA2197467A1 (fr) 1997-01-09
EP0776322B1 (fr) 2001-11-07
HUP9702399A3 (en) 1999-12-28
ES2168489T3 (es) 2002-06-16
JPH10505360A (ja) 1998-05-26
US5767282A (en) 1998-06-16
MX9701274A (es) 1997-05-31
WO1997000870A1 (fr) 1997-01-09
IL120165A0 (en) 1997-06-10
CA2197467C (fr) 2008-02-12
CN1179955C (zh) 2004-12-15
JP3889047B2 (ja) 2007-03-07
IL120165A (en) 2002-02-10
DE69616719D1 (de) 2001-12-13
CN1158126A (zh) 1997-08-27
AU712898B2 (en) 1999-11-18
EP1116718A2 (fr) 2001-07-18
EP0776322A1 (fr) 1997-06-04
NO970766D0 (no) 1997-02-19
EP1116718A3 (fr) 2001-08-29
HUP9702399A2 (hu) 1998-07-28
AU6221596A (en) 1997-01-22
GB9512471D0 (en) 1995-08-23

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