ZA964764B - (R)-(Z)-1-Azabicyclo ¬2.2.1¾ heptan-3-one 0-¬3-(3-methoxy-phenyl)-2-propynyl¾ oxime maleate as a pharmaceutical agent - Google Patents
(R)-(Z)-1-Azabicyclo ¬2.2.1¾ heptan-3-one 0-¬3-(3-methoxy-phenyl)-2-propynyl¾ oxime maleate as a pharmaceutical agentInfo
- Publication number
- ZA964764B ZA964764B ZA964764A ZA964764A ZA964764B ZA 964764 B ZA964764 B ZA 964764B ZA 964764 A ZA964764 A ZA 964764A ZA 964764 A ZA964764 A ZA 964764A ZA 964764 B ZA964764 B ZA 964764B
- Authority
- ZA
- South Africa
- Prior art keywords
- heptan
- azabicyclo
- methoxy
- phenyl
- pharmaceutical agent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/474,622 US5534522A (en) | 1995-06-07 | 1995-06-07 | (R)-(Z)-1-azabicyclo [2.2.1] heptan-3-one,O-[3-(3-methoxyphenyl)-2-propynyl] oxime maleate as a pharmaceutical agent |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA964764B true ZA964764B (en) | 1997-01-08 |
Family
ID=23884337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA964764A ZA964764B (en) | 1995-06-07 | 1996-06-06 | (R)-(Z)-1-Azabicyclo ¬2.2.1¾ heptan-3-one 0-¬3-(3-methoxy-phenyl)-2-propynyl¾ oxime maleate as a pharmaceutical agent |
Country Status (25)
Country | Link |
---|---|
US (1) | US5534522A (el) |
EP (1) | EP0839148B1 (el) |
JP (1) | JPH11506723A (el) |
KR (1) | KR100383031B1 (el) |
CN (1) | CN1063181C (el) |
AT (1) | ATE187967T1 (el) |
BG (1) | BG63571B1 (el) |
CA (1) | CA2219753A1 (el) |
CZ (1) | CZ286528B6 (el) |
DE (1) | DE69605800T2 (el) |
DK (1) | DK0839148T3 (el) |
EA (1) | EA000381B1 (el) |
EE (1) | EE03971B1 (el) |
ES (1) | ES2142586T3 (el) |
GE (1) | GEP19991874B (el) |
GR (1) | GR3032772T3 (el) |
HK (1) | HK1018055A1 (el) |
HU (1) | HUP9802499A3 (el) |
NO (1) | NO308901B1 (el) |
NZ (1) | NZ307946A (el) |
PL (1) | PL323796A1 (el) |
SK (1) | SK282824B6 (el) |
UA (1) | UA46032C2 (el) |
WO (1) | WO1996040687A1 (el) |
ZA (1) | ZA964764B (el) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9601909A (pt) * | 1995-07-13 | 1999-10-13 | Smithkline Beecham Corp | N,n-dietil-8,8-dipropil-2-azaspiro(4,5)decano-2-propan amina dimaleato |
US6528529B1 (en) | 1998-03-31 | 2003-03-04 | Acadia Pharmaceuticals Inc. | Compounds with activity on muscarinic receptors |
US7544681B2 (en) | 2001-09-27 | 2009-06-09 | Ramot At Tel Aviv University Ltd. | Conjugated psychotropic drugs and uses thereof |
KR20060058728A (ko) * | 2003-10-02 | 2006-05-30 | 파마시아 앤드 업존 캄파니 엘엘씨 | 피롤-치환된 인돌리논 화합물의 염 및 다형체 |
US7741358B2 (en) * | 2005-04-14 | 2010-06-22 | N.V. Organon | Crystal form of asenapine maleate |
WO2006131923A2 (en) * | 2005-06-07 | 2006-12-14 | Ramot At Tel Aviv University Ltd. | Novel salts of conjugated psychotropic drugs and processes of preparing same |
AU2006282896A1 (en) * | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
EP2382975A3 (en) | 2006-05-09 | 2012-02-29 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
US8377990B2 (en) | 2006-07-17 | 2013-02-19 | Ramot At Tel-Aviv University Ltd. | Conjugates comprising a psychotropic drug or a GABA agonist and an organic acid and their use in treating pain and other CNS disorders |
JP2010502722A (ja) | 2006-09-08 | 2010-01-28 | ブレインセルス,インコーポレイティド | 4−アシルアミノピリジン誘導体を含む組み合わせ |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
WO2009101616A1 (en) | 2008-02-11 | 2009-08-20 | Ramot At Tel Aviv University Ltd. | Novel conjugates for treating neurodegenerative diseases and disorders |
WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
JP2013513600A (ja) | 2009-12-09 | 2013-04-22 | バイオラインアールエックス リミテッド | 認知機能改善方法 |
MX2012009821A (es) | 2010-02-24 | 2012-10-09 | Univ Ramot | Formas cristalinas de la sal de tri-mesilato de perfenazina-gaba y proceso para producirlas. |
US8916610B2 (en) | 2010-09-22 | 2014-12-23 | Ramot At Tel-Aviv University Ltd. | Acid addition salt of a nortriptyline-GABA conjugate and a process of preparing same |
JP5997931B2 (ja) * | 2011-05-25 | 2016-09-28 | 石原産業株式会社 | 農園芸用殺菌剤組成物及び植物病害の防除方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5346911A (en) * | 1990-03-06 | 1994-09-13 | Warner-Lambert Company | Azabicyclo and azacyclo oxime and amine cholinergic agents and methods of treatment |
US5306718A (en) * | 1990-03-06 | 1994-04-26 | Warner-Lambert Company | Oxime and amine substituted azabicyclo and azocyclo muscarinic agonists and methods of treatment |
-
1995
- 1995-06-07 US US08/474,622 patent/US5534522A/en not_active Expired - Fee Related
-
1996
- 1996-05-13 NZ NZ307946A patent/NZ307946A/en unknown
- 1996-05-13 DK DK96915757T patent/DK0839148T3/da active
- 1996-05-13 DE DE69605800T patent/DE69605800T2/de not_active Expired - Fee Related
- 1996-05-13 CZ CZ19973817A patent/CZ286528B6/cs not_active IP Right Cessation
- 1996-05-13 EA EA199800007A patent/EA000381B1/ru not_active IP Right Cessation
- 1996-05-13 KR KR1019970709053A patent/KR100383031B1/ko not_active IP Right Cessation
- 1996-05-13 UA UA98010040A patent/UA46032C2/uk unknown
- 1996-05-13 GE GEAP19964088A patent/GEP19991874B/en unknown
- 1996-05-13 JP JP9500555A patent/JPH11506723A/ja active Pending
- 1996-05-13 SK SK1644-97A patent/SK282824B6/sk unknown
- 1996-05-13 CN CN96194436A patent/CN1063181C/zh not_active Expired - Fee Related
- 1996-05-13 WO PCT/US1996/006814 patent/WO1996040687A1/en active IP Right Grant
- 1996-05-13 EE EE9700316A patent/EE03971B1/xx not_active IP Right Cessation
- 1996-05-13 HU HU9802499A patent/HUP9802499A3/hu unknown
- 1996-05-13 CA CA002219753A patent/CA2219753A1/en not_active Abandoned
- 1996-05-13 PL PL96323796A patent/PL323796A1/xx unknown
- 1996-05-13 AT AT96915757T patent/ATE187967T1/de not_active IP Right Cessation
- 1996-05-13 ES ES96915757T patent/ES2142586T3/es not_active Expired - Lifetime
- 1996-05-13 EP EP96915757A patent/EP0839148B1/en not_active Expired - Lifetime
- 1996-06-06 ZA ZA964764A patent/ZA964764B/xx unknown
-
1997
- 1997-11-27 BG BG102078A patent/BG63571B1/bg unknown
- 1997-12-05 NO NO975704A patent/NO308901B1/no not_active IP Right Cessation
-
1998
- 1998-12-15 HK HK98113383A patent/HK1018055A1/xx not_active IP Right Cessation
-
2000
- 2000-02-28 GR GR20000400474T patent/GR3032772T3/el not_active IP Right Cessation
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