ZA961954B - Heterocyclic substituted piperazinone derivatives - Google Patents

Heterocyclic substituted piperazinone derivatives

Info

Publication number
ZA961954B
ZA961954B ZA961954A ZA961954A ZA961954B ZA 961954 B ZA961954 B ZA 961954B ZA 961954 A ZA961954 A ZA 961954A ZA 961954 A ZA961954 A ZA 961954A ZA 961954 B ZA961954 B ZA 961954B
Authority
ZA
South Africa
Prior art keywords
heterocyclic substituted
piperazinone derivatives
substituted piperazinone
derivatives
heterocyclic
Prior art date
Application number
ZA961954A
Other languages
English (en)
Inventor
Timothy Paul Burkholder
Elizabeth Mary Kudlacz
Tieu-Binh Le
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of ZA961954B publication Critical patent/ZA961954B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
ZA961954A 1995-03-15 1996-03-11 Heterocyclic substituted piperazinone derivatives ZA961954B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40478895A 1995-03-15 1995-03-15

Publications (1)

Publication Number Publication Date
ZA961954B true ZA961954B (en) 1996-09-17

Family

ID=23601038

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA961954A ZA961954B (en) 1995-03-15 1996-03-11 Heterocyclic substituted piperazinone derivatives

Country Status (21)

Country Link
US (2) US5840726A (xx)
EP (1) EP0815105B1 (xx)
JP (1) JP3825472B2 (xx)
KR (1) KR19980703032A (xx)
CN (1) CN1067068C (xx)
AR (1) AR002715A1 (xx)
AT (1) ATE206421T1 (xx)
AU (1) AU697599B2 (xx)
CA (1) CA2215333C (xx)
DE (1) DE69615670T2 (xx)
DK (1) DK0815105T3 (xx)
ES (1) ES2164235T3 (xx)
FI (1) FI973671A (xx)
HU (1) HUP9702149A3 (xx)
IL (1) IL117453A (xx)
NO (1) NO314693B1 (xx)
NZ (1) NZ302948A (xx)
PT (1) PT815105E (xx)
TW (1) TW464647B (xx)
WO (1) WO1996028441A1 (xx)
ZA (1) ZA961954B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2240835A1 (en) * 1995-12-18 1997-06-26 Fujisawa Pharmaceutical Co., Ltd. Piperazine derivatives as tachykinin antagonists
DE19939910A1 (de) * 1999-08-23 2001-03-01 Morphochem Ag Neue Verbindungen, die Tryptase-Aktivität hemmen
US7456222B2 (en) * 2002-05-17 2008-11-25 Sequella, Inc. Anti tubercular drug: compositions and methods
US20040033986A1 (en) * 2002-05-17 2004-02-19 Protopopova Marina Nikolaevna Anti tubercular drug: compositions and methods
CN101404986B (zh) * 2002-05-17 2011-09-28 赛奎拉公司 用于诊断和治疗感染性疾病的组合物和制药方法
WO2005034857A2 (en) * 2003-09-05 2005-04-21 Sequella, Inc. Methods and compositions comprising diamines as new anti-tubercular therapeutics
US20090281054A1 (en) * 2008-05-06 2009-11-12 Venkata Reddy Compositions and methods comprising capuramycin analogues

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3132882A1 (de) * 1981-08-20 1983-03-03 Cassella Ag, 6000 Frankfurt Neue piperazinone, ihre herstellung und verwendung
IE903957A1 (en) * 1989-11-06 1991-05-08 Sanofi Sa Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present
IL99320A (en) * 1990-09-05 1995-07-31 Sanofi Sa Arylalkylamines, their preparation and pharmaceutical preparations containing them
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
WO1994003483A1 (en) * 1992-07-30 1994-02-17 Chiron Corporation Endothelin receptor-binding compounds
GB9222486D0 (en) * 1992-10-26 1992-12-09 Merck Sharp & Dohme Therapeutic agents
CN1081635C (zh) * 1993-05-06 2002-03-27 默里尔药物公司 取代的吡咯烷 -3-基-烷基-哌啶
IL111730A (en) * 1993-11-29 1998-12-06 Fujisawa Pharmaceutical Co Piperazine derivatives, processes for their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
FI973671A0 (fi) 1997-09-12
IL117453A (en) 2000-07-26
ATE206421T1 (de) 2001-10-15
DK0815105T3 (da) 2002-01-21
MX9706872A (es) 1997-11-29
EP0815105A1 (en) 1998-01-07
NO314693B1 (no) 2003-05-05
HUP9702149A3 (en) 1999-07-28
KR19980703032A (ko) 1998-09-05
US5864045A (en) 1999-01-26
DE69615670T2 (de) 2002-08-08
NO974205L (no) 1997-11-13
NO974205D0 (no) 1997-09-12
CA2215333A1 (en) 1996-09-19
AR002715A1 (es) 1998-04-29
PT815105E (pt) 2002-03-28
NZ302948A (en) 2001-05-25
DE69615670D1 (de) 2001-11-08
IL117453A0 (en) 1996-07-23
WO1996028441A1 (en) 1996-09-19
EP0815105B1 (en) 2001-10-04
ES2164235T3 (es) 2002-02-16
HUP9702149A2 (hu) 1999-06-28
AU4930696A (en) 1996-10-02
US5840726A (en) 1998-11-24
JPH11501917A (ja) 1999-02-16
TW464647B (en) 2001-11-21
CA2215333C (en) 2002-01-01
CN1178529A (zh) 1998-04-08
JP3825472B2 (ja) 2006-09-27
CN1067068C (zh) 2001-06-13
AU697599B2 (en) 1998-10-08
FI973671A (fi) 1997-09-12

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