NO974205L - Heterocyklisk-substituerte piperazinonderivater som tachykininreceptor-antagonister - Google Patents
Heterocyklisk-substituerte piperazinonderivater som tachykininreceptor-antagonisterInfo
- Publication number
- NO974205L NO974205L NO974205A NO974205A NO974205L NO 974205 L NO974205 L NO 974205L NO 974205 A NO974205 A NO 974205A NO 974205 A NO974205 A NO 974205A NO 974205 L NO974205 L NO 974205L
- Authority
- NO
- Norway
- Prior art keywords
- heterocyclic
- receptor antagonists
- piperazine derivatives
- substituted piperazine
- tachykinin receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40478895A | 1995-03-15 | 1995-03-15 | |
| PCT/US1996/001437 WO1996028441A1 (en) | 1995-03-15 | 1996-02-06 | Heterocyclic substituted piperazinone derivatives as tachykinin receptor antagonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO974205D0 NO974205D0 (no) | 1997-09-12 |
| NO974205L true NO974205L (no) | 1997-11-13 |
| NO314693B1 NO314693B1 (no) | 2003-05-05 |
Family
ID=23601038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19974205A NO314693B1 (no) | 1995-03-15 | 1997-09-12 | Heterosyklisk-substituerte piperazinonderivater til fremstilling av takykininreseptorantagonister, fremgangsmåte for fremstilling av disseforbindelser, nye mellomprodukter og farmasöytiske preparater inneholdende de nyepiperazinonderivater |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US5840726A (no) |
| EP (1) | EP0815105B1 (no) |
| JP (1) | JP3825472B2 (no) |
| KR (1) | KR19980703032A (no) |
| CN (1) | CN1067068C (no) |
| AR (1) | AR002715A1 (no) |
| AT (1) | ATE206421T1 (no) |
| AU (1) | AU697599B2 (no) |
| CA (1) | CA2215333C (no) |
| DE (1) | DE69615670T2 (no) |
| DK (1) | DK0815105T3 (no) |
| ES (1) | ES2164235T3 (no) |
| FI (1) | FI973671A0 (no) |
| HU (1) | HUP9702149A3 (no) |
| IL (1) | IL117453A (no) |
| NO (1) | NO314693B1 (no) |
| NZ (1) | NZ302948A (no) |
| PT (1) | PT815105E (no) |
| TW (1) | TW464647B (no) |
| WO (1) | WO1996028441A1 (no) |
| ZA (1) | ZA961954B (no) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2240835A1 (en) * | 1995-12-18 | 1997-06-26 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine derivatives as tachykinin antagonists |
| DE19939910A1 (de) * | 1999-08-23 | 2001-03-01 | Morphochem Ag | Neue Verbindungen, die Tryptase-Aktivität hemmen |
| US20040033986A1 (en) * | 2002-05-17 | 2004-02-19 | Protopopova Marina Nikolaevna | Anti tubercular drug: compositions and methods |
| US7456222B2 (en) * | 2002-05-17 | 2008-11-25 | Sequella, Inc. | Anti tubercular drug: compositions and methods |
| CN101404986B (zh) * | 2002-05-17 | 2011-09-28 | 赛奎拉公司 | 用于诊断和治疗感染性疾病的组合物和制药方法 |
| US7884097B2 (en) * | 2003-09-05 | 2011-02-08 | Sequella, Inc. | Methods and compositions comprising diamines as new anti-tubercular therapeutics |
| WO2009136965A1 (en) * | 2008-05-06 | 2009-11-12 | Sequella, Inc. | Compositions and methods comprising capuramycin analogues |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3132882A1 (de) * | 1981-08-20 | 1983-03-03 | Cassella Ag, 6000 Frankfurt | Neue piperazinone, ihre herstellung und verwendung |
| FI97540C (fi) * | 1989-11-06 | 1997-01-10 | Sanofi Sa | Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi |
| IL99320A (en) * | 1990-09-05 | 1995-07-31 | Sanofi Sa | Arylalkylamines, their preparation and pharmaceutical preparations containing them |
| FR2676055B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| WO1994003483A1 (en) * | 1992-07-30 | 1994-02-17 | Chiron Corporation | Endothelin receptor-binding compounds |
| GB9222486D0 (en) * | 1992-10-26 | 1992-12-09 | Merck Sharp & Dohme | Therapeutic agents |
| HU224496B1 (hu) * | 1993-05-06 | 2005-10-28 | Merrel Dow Pharmaceuticals Inc. | Pirrolidin-3-il-alkil-piperidin-származékok és e vegyületeket tartalmazó gyógyászati készítmények |
| IL111730A (en) * | 1993-11-29 | 1998-12-06 | Fujisawa Pharmaceutical Co | Piperazine derivatives, processes for their preparation and pharmaceutical preparations containing them |
-
1996
- 1996-02-06 NZ NZ302948A patent/NZ302948A/en unknown
- 1996-02-06 AT AT96905333T patent/ATE206421T1/de not_active IP Right Cessation
- 1996-02-06 KR KR1019970706440A patent/KR19980703032A/ko not_active Application Discontinuation
- 1996-02-06 ES ES96905333T patent/ES2164235T3/es not_active Expired - Lifetime
- 1996-02-06 CA CA002215333A patent/CA2215333C/en not_active Expired - Fee Related
- 1996-02-06 PT PT96905333T patent/PT815105E/pt unknown
- 1996-02-06 CN CN96192564A patent/CN1067068C/zh not_active Expired - Fee Related
- 1996-02-06 WO PCT/US1996/001437 patent/WO1996028441A1/en not_active Application Discontinuation
- 1996-02-06 EP EP96905333A patent/EP0815105B1/en not_active Expired - Lifetime
- 1996-02-06 HU HU9702149A patent/HUP9702149A3/hu unknown
- 1996-02-06 DK DK96905333T patent/DK0815105T3/da active
- 1996-02-06 JP JP52757896A patent/JP3825472B2/ja not_active Expired - Fee Related
- 1996-02-06 DE DE69615670T patent/DE69615670T2/de not_active Expired - Lifetime
- 1996-02-06 AU AU49306/96A patent/AU697599B2/en not_active Ceased
- 1996-03-11 ZA ZA961954A patent/ZA961954B/xx unknown
- 1996-03-12 IL IL11745396A patent/IL117453A/xx not_active IP Right Cessation
- 1996-03-12 TW TW085102987A patent/TW464647B/zh active
- 1996-03-12 AR ARP960101710A patent/AR002715A1/es active IP Right Grant
-
1997
- 1997-06-19 US US08/878,695 patent/US5840726A/en not_active Expired - Lifetime
- 1997-09-12 FI FI973671A patent/FI973671A0/fi not_active IP Right Cessation
- 1997-09-12 NO NO19974205A patent/NO314693B1/no unknown
-
1998
- 1998-04-27 US US09/067,386 patent/US5864045A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AR002715A1 (es) | 1998-04-29 |
| CN1067068C (zh) | 2001-06-13 |
| FI973671A (fi) | 1997-09-12 |
| AU697599B2 (en) | 1998-10-08 |
| CA2215333A1 (en) | 1996-09-19 |
| PT815105E (pt) | 2002-03-28 |
| HUP9702149A3 (en) | 1999-07-28 |
| NO314693B1 (no) | 2003-05-05 |
| NZ302948A (en) | 2001-05-25 |
| DK0815105T3 (da) | 2002-01-21 |
| EP0815105B1 (en) | 2001-10-04 |
| DE69615670T2 (de) | 2002-08-08 |
| US5840726A (en) | 1998-11-24 |
| ATE206421T1 (de) | 2001-10-15 |
| TW464647B (en) | 2001-11-21 |
| CA2215333C (en) | 2002-01-01 |
| IL117453A (en) | 2000-07-26 |
| WO1996028441A1 (en) | 1996-09-19 |
| CN1178529A (zh) | 1998-04-08 |
| AU4930696A (en) | 1996-10-02 |
| US5864045A (en) | 1999-01-26 |
| DE69615670D1 (de) | 2001-11-08 |
| IL117453A0 (en) | 1996-07-23 |
| MX9706872A (es) | 1997-11-29 |
| EP0815105A1 (en) | 1998-01-07 |
| FI973671A0 (fi) | 1997-09-12 |
| ES2164235T3 (es) | 2002-02-16 |
| KR19980703032A (ko) | 1998-09-05 |
| HUP9702149A2 (hu) | 1999-06-28 |
| JP3825472B2 (ja) | 2006-09-27 |
| JPH11501917A (ja) | 1999-02-16 |
| NO974205D0 (no) | 1997-09-12 |
| ZA961954B (en) | 1996-09-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0804419T3 (da) | Quinolinderivater som tachykinin NK 3-receptor-antagonister | |
| NZ307625A (en) | 1-benzoyl-2-(indolyl-3-alkyl)-piperazine derivatives as neurokinin receptor antagonists | |
| NO951613D0 (no) | Ikke-peptidyl tachykinin reseptorantagonister | |
| DK0856001T3 (da) | Pyrimidinderivater som 5-HT2C-receptor-antagonister | |
| AU5417296A (en) | Novel substituted piperazine derivatives having tachykinin receptor antagonists activity | |
| FI973205A (fi) | Indolijohdannaisia 5-HT-reseptoriantagonisteina | |
| DK0901470T3 (da) | Indolderivater egnede som endothelinreceptorantagonister | |
| ATE201016T1 (de) | Pyrimidindion-, pyrimidintrion-, triazindion- derivate als alpha-1-adrenergische rezeptorantagonisten | |
| NO974043D0 (no) | Indolderivater som EAA-antagonister | |
| DK1027342T3 (da) | Cyclopentenderivater som motilinreceptorantagonister | |
| DK0869955T3 (da) | N-acyl-2-substituerede-4-(benzimidazolyl- eller midazopyridinyl- substituerede grupper)-piperidiner som tachykinin-antagonister | |
| NO985970D0 (no) | Indolinderivater anvendelige som 5_HT-2C-reseptor-antagonister | |
| ID24468A (id) | 2-asilaminopropanamina sebagai antagonis reseptor tachykinin | |
| FI951798A0 (fi) | Bentsofuraanijohdannaiset 5-HT1-kaltaisina reseptoriantagonisteina | |
| NO974205D0 (no) | Heterocyklisk-substituerte piperazinonderivater som tachykininreceptor-antagonister | |
| NO992066D0 (no) | Piperazinoderivater som neurokininantagonister | |
| NO961333D0 (no) | Nye pyrazolderivater som angiotensin-II-antagonister | |
| NO985972L (no) | Indolinderivater anvendelige som 5-HT-2C reseptorantagonister | |
| ID24309A (id) | 2-asilaminopropanamina sebagai antagonis reseptor tachykinin | |
| DE69617010D1 (de) | Isazole derivate als fibrinogen-rezeptor-antagonisten | |
| NO20002575D0 (no) | Substituerte oksimer som neurokininantagonister | |
| NO943101D0 (no) | 2,6-metano-2H-kinolizinderivat som 5-HT3-reseptorantagonist | |
| FI941118A0 (fi) | Bentsyyli-imidatsopyridiinijohdannainen angiotensiini II reseptoriantagonistina | |
| DK0940391T3 (da) | Quinolinderivater som tachykinin-NK3-receptor-antagonister | |
| FI941117A (fi) | Bentsyyli-imidatsopyridiinijohdannaiset angiotensiini II reseptoriantagonisteina |