ZA954947B - Novel substituted alkyldiamine derivatives - Google Patents

Novel substituted alkyldiamine derivatives

Info

Publication number
ZA954947B
ZA954947B ZA954947A ZA954947A ZA954947B ZA 954947 B ZA954947 B ZA 954947B ZA 954947 A ZA954947 A ZA 954947A ZA 954947 A ZA954947 A ZA 954947A ZA 954947 B ZA954947 B ZA 954947B
Authority
ZA
South Africa
Prior art keywords
novel substituted
substituted alkyldiamine
derivatives
alkyldiamine derivatives
useful
Prior art date
Application number
ZA954947A
Other languages
English (en)
Inventor
Timothy Paul Burkholder
Elizabeth Mary Kudlacz
Tieu-Binh Le
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA954947B publication Critical patent/ZA954947B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/64Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/78Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/52Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the nitrogen atom of at least one of the carboxamide groups further acylated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
ZA954947A 1994-06-20 1995-06-14 Novel substituted alkyldiamine derivatives ZA954947B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/262,209 US5597845A (en) 1994-06-20 1994-06-20 Substituted alkyldiamine derivatives

Publications (1)

Publication Number Publication Date
ZA954947B true ZA954947B (en) 1996-01-31

Family

ID=22996631

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA954947A ZA954947B (en) 1994-06-20 1995-06-14 Novel substituted alkyldiamine derivatives

Country Status (20)

Country Link
US (1) US5597845A (zh)
EP (1) EP0767783B1 (zh)
JP (1) JP3920916B2 (zh)
KR (1) KR100371981B1 (zh)
CN (1) CN1083429C (zh)
AT (1) ATE169905T1 (zh)
AU (1) AU691619B2 (zh)
CA (1) CA2193348C (zh)
DE (1) DE69504198T2 (zh)
DK (1) DK0767783T3 (zh)
ES (1) ES2121389T3 (zh)
FI (1) FI115135B (zh)
HU (1) HUT75965A (zh)
IL (1) IL114185A (zh)
MX (1) MX9606654A (zh)
NO (1) NO307458B1 (zh)
NZ (1) NZ287291A (zh)
TW (1) TW442451B (zh)
WO (1) WO1995035279A1 (zh)
ZA (1) ZA954947B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW541295B (en) * 1999-01-05 2003-07-11 Nippon Zoki Pharmaceutical Co A novel substituted alkylteraamine derivative for use as tachykinin antagonist
US7423177B2 (en) 2001-03-05 2008-09-09 Transtech Pharma, Inc. Carboxamide derivatives as therapeutic agents
US6613801B2 (en) 2000-05-30 2003-09-02 Transtech Pharma, Inc. Method for the synthesis of compounds of formula I and their uses thereof
AU2002245590B2 (en) 2001-03-05 2006-06-29 Transtech Pharma, Inc. Benzimidazole derivatives as therapeutic agents
EP2324830A1 (en) 2002-03-05 2011-05-25 TransTech Pharma Inc. Process for the preparation of a monocyclic azole derivative that inhibits the interaction of ligands with rage
US20090263370A1 (en) * 2006-11-30 2009-10-22 Guoliang Tao Methods for treating tachykinin-mediated diseases with cholinesterase
TWI517850B (zh) 2009-09-30 2016-01-21 Vtv治療有限責任公司 經取代之咪唑衍生物及其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164372A (en) * 1989-04-28 1992-11-17 Fujisawa Pharmaceutical Company, Ltd. Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same
WO1994004494A1 (en) * 1992-08-13 1994-03-03 Warner-Lambert Company Tachykinin antagonists
US5472978A (en) * 1991-07-05 1995-12-05 Merck Sharp & Dohme Ltd. Aromatic compounds, pharmaceutical compositions containing them and their use in therapy

Also Published As

Publication number Publication date
NZ287291A (en) 1998-10-28
NO965469L (no) 1997-02-19
IL114185A0 (zh) 1995-10-31
IL114185A (en) 1999-07-14
MX9606654A (es) 1997-12-31
WO1995035279A1 (en) 1995-12-28
DE69504198T2 (de) 1999-04-29
CA2193348C (en) 1999-08-24
ATE169905T1 (de) 1998-09-15
JPH10501551A (ja) 1998-02-10
CA2193348A1 (en) 1995-12-28
CN1083429C (zh) 2002-04-24
TW442451B (en) 2001-06-23
EP0767783B1 (en) 1998-08-19
HU9603540D0 (en) 1997-02-28
FI965097A0 (fi) 1996-12-18
NO965469D0 (no) 1996-12-19
CN1155883A (zh) 1997-07-30
NO307458B1 (no) 2000-04-10
HUT75965A (en) 1997-05-28
ES2121389T3 (es) 1998-11-16
AU691619B2 (en) 1998-05-21
FI115135B (fi) 2005-03-15
DK0767783T3 (da) 1999-05-25
FI965097A (fi) 1996-12-18
AU2596195A (en) 1996-01-15
JP3920916B2 (ja) 2007-05-30
EP0767783A1 (en) 1997-04-16
US5597845A (en) 1997-01-28
KR100371981B1 (ko) 2003-06-12
DE69504198D1 (de) 1998-09-24

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