ZA949921B - Chemical compounds - Google Patents
Chemical compoundsInfo
- Publication number
- ZA949921B ZA949921B ZA949921A ZA949921A ZA949921B ZA 949921 B ZA949921 B ZA 949921B ZA 949921 A ZA949921 A ZA 949921A ZA 949921 A ZA949921 A ZA 949921A ZA 949921 B ZA949921 B ZA 949921B
- Authority
- ZA
- South Africa
- Prior art keywords
- group
- formula
- pct
- compound
- hydroxyl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 229930003316 Vitamin D Natural products 0.000 abstract 2
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 235000019166 vitamin D Nutrition 0.000 abstract 2
- 239000011710 vitamin D Substances 0.000 abstract 2
- -1 vitamin D amine Chemical class 0.000 abstract 2
- 229940046008 vitamin d Drugs 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000004419 alkynylene group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 230000000668 effect on calcium Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000000640 hydroxylating effect Effects 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 150000003710 vitamin D derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Nutrition Science (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939325415A GB9325415D0 (en) | 1993-12-13 | 1993-12-13 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA949921B true ZA949921B (en) | 1995-10-12 |
Family
ID=10746493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA949921A ZA949921B (en) | 1993-12-13 | 1994-12-13 | Chemical compounds |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5786347A (cs) |
| EP (1) | EP0734376B1 (cs) |
| JP (1) | JP3779991B2 (cs) |
| KR (1) | KR100399661B1 (cs) |
| CN (1) | CN1080718C (cs) |
| AT (1) | ATE196468T1 (cs) |
| AU (1) | AU681223B2 (cs) |
| CA (1) | CA2178090A1 (cs) |
| CZ (1) | CZ291623B6 (cs) |
| DE (1) | DE69425980T2 (cs) |
| DK (1) | DK0734376T3 (cs) |
| ES (1) | ES2149957T3 (cs) |
| FI (1) | FI112360B (cs) |
| GB (1) | GB9325415D0 (cs) |
| GR (1) | GR3035028T3 (cs) |
| HU (1) | HU223469B1 (cs) |
| IL (1) | IL111975A (cs) |
| NO (1) | NO313800B1 (cs) |
| NZ (1) | NZ277086A (cs) |
| PT (1) | PT734376E (cs) |
| WO (1) | WO1995016672A1 (cs) |
| ZA (1) | ZA949921B (cs) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19619036A1 (de) * | 1996-04-30 | 1997-11-13 | Schering Ag | Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
| KR20010012770A (ko) * | 1997-05-22 | 2001-02-26 | 세파론, 인코포레이티드 | 비타민 ｄ 유사체 및 그 뉴런 효과 |
| US6043385A (en) * | 1997-12-16 | 2000-03-28 | Hoffman-La Roche Inc. | Vitamin D derivatives |
| DE19935771A1 (de) * | 1999-07-23 | 2001-02-01 | Schering Ag | Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
| US6989377B2 (en) | 1999-12-21 | 2006-01-24 | Wisconsin Alumni Research Foundation | Treating vitamin D responsive diseases |
| US6358939B1 (en) | 1999-12-21 | 2002-03-19 | Northern Lights Pharmaceuticals, Llc | Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease |
| WO2002028862A2 (en) | 2000-10-02 | 2002-04-11 | Emory University | Triptolide analogs for the treatment of autoimmune and inflammatory disorders |
| WO2005027928A1 (en) * | 2003-09-19 | 2005-03-31 | Pfizer Products Inc. | 2-alkylidene-19-nor-vit amin d derivatives for the treatment of hypocalcemic tetany or hyproparathyroidism |
| TW200714580A (en) * | 2005-10-14 | 2007-04-16 | Formosa Lab Inc | Process for preparing vitamin D analogs |
| AU2010208323B2 (en) | 2009-01-27 | 2016-03-10 | Berg Llc | Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy |
| CA2770683C (en) | 2009-08-14 | 2018-09-04 | Berg Biosystems, Llc | Vitamin d3 and analogs thereof for treating alopecia |
| WO2012158794A1 (en) | 2011-05-17 | 2012-11-22 | Wisconsin Alumni Research Foundation | N-cyclopropyl-(20r)-2-methylene-19,26,27-trinor-25-aza-vitamin d analogs and their uses |
| US8785603B2 (en) | 2011-05-20 | 2014-07-22 | Siemens Healthcare Diagnostics Inc. | Antibodies to 25-hydroxyvitamin D2 and D3 and uses thereof |
| US9244083B2 (en) | 2012-11-30 | 2016-01-26 | Siemens Healthcare Diagnostics Inc. | Compositions and methods for detecting vitamin D |
| US9618523B2 (en) | 2013-02-28 | 2017-04-11 | Siemens Healthcare Diagnostics Inc. | Methods and reagents for determining isomeric analytes |
| WO2014194133A1 (en) | 2013-05-29 | 2014-12-04 | Berg Llc | Preventing or mitigating chemotherapy induced alopecia using vitamin d |
| EP3802507A1 (en) * | 2018-05-30 | 2021-04-14 | Translate Bio, Inc. | Vitamin cationic lipids |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2083771T3 (es) * | 1991-11-07 | 1996-04-16 | Res Inst Medicine Chem | Derivados amidicos de la vitamina d. |
| JPH06107625A (ja) * | 1992-01-13 | 1994-04-19 | Asahi Chem Ind Co Ltd | 新規な１α、２５−ジヒドロキシビタミンＤ誘導体、およびその製造法 |
-
1993
- 1993-12-13 GB GB939325415A patent/GB9325415D0/en active Pending
-
1994
- 1994-12-13 HU HU9601622A patent/HU223469B1/hu not_active IP Right Cessation
- 1994-12-13 ZA ZA949921A patent/ZA949921B/xx unknown
- 1994-12-13 EP EP95902896A patent/EP0734376B1/en not_active Expired - Lifetime
- 1994-12-13 CZ CZ19961704A patent/CZ291623B6/cs not_active IP Right Cessation
- 1994-12-13 NZ NZ277086A patent/NZ277086A/en unknown
- 1994-12-13 IL IL11197594A patent/IL111975A/xx not_active IP Right Cessation
- 1994-12-13 CA CA002178090A patent/CA2178090A1/en not_active Abandoned
- 1994-12-13 DE DE69425980T patent/DE69425980T2/de not_active Expired - Fee Related
- 1994-12-13 DK DK95902896T patent/DK0734376T3/da active
- 1994-12-13 KR KR1019960703082A patent/KR100399661B1/ko not_active Expired - Fee Related
- 1994-12-13 US US08/652,597 patent/US5786347A/en not_active Expired - Fee Related
- 1994-12-13 WO PCT/GB1994/002725 patent/WO1995016672A1/en active IP Right Grant
- 1994-12-13 CN CN94194822A patent/CN1080718C/zh not_active Expired - Fee Related
- 1994-12-13 JP JP51660195A patent/JP3779991B2/ja not_active Expired - Fee Related
- 1994-12-13 AU AU12158/95A patent/AU681223B2/en not_active Ceased
- 1994-12-13 AT AT95902896T patent/ATE196468T1/de not_active IP Right Cessation
- 1994-12-13 ES ES95902896T patent/ES2149957T3/es not_active Expired - Lifetime
- 1994-12-13 PT PT95902896T patent/PT734376E/pt unknown
-
1996
- 1996-06-12 FI FI962440A patent/FI112360B/fi not_active IP Right Cessation
- 1996-06-12 NO NO19962479A patent/NO313800B1/no not_active IP Right Cessation
-
2000
- 2000-12-12 GR GR20000402715T patent/GR3035028T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI112360B (fi) | 2003-11-28 |
| IL111975A (en) | 1999-07-14 |
| JP3779991B2 (ja) | 2006-05-31 |
| US5786347A (en) | 1998-07-28 |
| WO1995016672A1 (en) | 1995-06-22 |
| GR3035028T3 (en) | 2001-03-30 |
| FI962440A0 (fi) | 1996-06-12 |
| EP0734376B1 (en) | 2000-09-20 |
| FI962440A7 (fi) | 1996-06-12 |
| CA2178090A1 (en) | 1995-06-22 |
| NZ277086A (en) | 1997-04-24 |
| DE69425980T2 (de) | 2001-02-08 |
| CZ170496A3 (en) | 1997-02-12 |
| HU9601622D0 (en) | 1996-08-28 |
| JPH09511224A (ja) | 1997-11-11 |
| PT734376E (pt) | 2000-12-29 |
| AU681223B2 (en) | 1997-08-21 |
| ATE196468T1 (de) | 2000-10-15 |
| NO313800B1 (no) | 2002-12-02 |
| AU1215895A (en) | 1995-07-03 |
| HU223469B1 (hu) | 2004-07-28 |
| NO962479D0 (no) | 1996-06-12 |
| DE69425980D1 (de) | 2000-10-26 |
| HUT75515A (en) | 1997-05-28 |
| DK0734376T3 (da) | 2000-12-11 |
| NO962479L (no) | 1996-08-12 |
| EP0734376A1 (en) | 1996-10-02 |
| CZ291623B6 (cs) | 2003-04-16 |
| CN1141625A (zh) | 1997-01-29 |
| CN1080718C (zh) | 2002-03-13 |
| GB9325415D0 (en) | 1994-02-16 |
| KR100399661B1 (ko) | 2004-04-30 |
| ES2149957T3 (es) | 2000-11-16 |
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