ZA942383B - New indole derivatives - Google Patents

New indole derivatives

Info

Publication number
ZA942383B
ZA942383B ZA942383A ZA942383A ZA942383B ZA 942383 B ZA942383 B ZA 942383B ZA 942383 A ZA942383 A ZA 942383A ZA 942383 A ZA942383 A ZA 942383A ZA 942383 B ZA942383 B ZA 942383B
Authority
ZA
South Africa
Prior art keywords
indole derivatives
new indole
new
derivatives
indole
Prior art date
Application number
ZA942383A
Other languages
English (en)
Inventor
Myrna Gil Quintero
Vincenzo Martino
Franco Borsini
Carlo-Maria Pellegrini
Marco Turconi
Ettore Giraldo
Original Assignee
Boehringer Ingelheim Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Italia filed Critical Boehringer Ingelheim Italia
Publication of ZA942383B publication Critical patent/ZA942383B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
ZA942383A 1993-04-08 1994-04-07 New indole derivatives ZA942383B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI930699A IT1271352B (it) 1993-04-08 1993-04-08 Derivati dell'indolo utili nel trattamento dei disturbi del sistema nervoso centrale

Publications (1)

Publication Number Publication Date
ZA942383B true ZA942383B (en) 1995-10-09

Family

ID=11365694

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA942383A ZA942383B (en) 1993-04-08 1994-04-07 New indole derivatives

Country Status (20)

Country Link
US (1) US5834493A (zh)
EP (1) EP0694033A1 (zh)
JP (1) JPH08508738A (zh)
CN (1) CN1124960A (zh)
AU (1) AU684276B2 (zh)
BG (1) BG100040A (zh)
BR (1) BR9406206A (zh)
CA (1) CA2160020A1 (zh)
CZ (1) CZ283398B6 (zh)
FI (1) FI954734A (zh)
HU (1) HUT74090A (zh)
IL (1) IL109234A (zh)
IT (1) IT1271352B (zh)
NO (1) NO953967L (zh)
NZ (1) NZ265055A (zh)
PL (1) PL310995A1 (zh)
SG (1) SG50507A1 (zh)
SK (1) SK119795A3 (zh)
WO (1) WO1994024125A1 (zh)
ZA (1) ZA942383B (zh)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9420521D0 (en) * 1994-10-12 1994-11-30 Smithkline Beecham Plc Novel compounds
IL132461A (en) * 1997-05-09 2003-09-17 Lundbeck & Co As H Method of manufacturing sertindole
EP1047692B1 (en) 1998-01-14 2004-07-21 The Uab Research Foundation Methods of synthesizing and screening inhibitors of bacterial nad synthetase enzyme, compounds thereof and methods of treating bacterial and microbial infections with these inhibitors
US6861448B2 (en) * 1998-01-14 2005-03-01 Virtual Drug Development, Inc. NAD synthetase inhibitors and uses thereof
US6673827B1 (en) 1999-06-29 2004-01-06 The Uab Research Foundation Methods of treating fungal infections with inhibitors of NAD synthetase enzyme
US6133287A (en) * 1998-03-24 2000-10-17 Allelix Biopharmaceuticals Inc. Piperidine-indole compounds having 5-HT6 affinity
AU3386299A (en) * 1998-04-08 1999-10-25 American Home Products Corporation N-aryloxyethylamine derivatives for the treatment of depression
WO1999055697A1 (en) * 1998-04-29 1999-11-04 American Home Products Corporation Serotonergic agents
FR2799463B1 (fr) * 1999-10-12 2004-04-16 Adir Nouveaux composes cyano-indoles inhibiteurs de recapture de serotonine, leur procede de preparation et ces compositions pharmaceutiques qui les contiennent
DE19951360A1 (de) * 1999-10-26 2001-05-03 Aventis Pharma Gmbh Substituierte Indole
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
DK1355900T3 (da) * 2000-12-22 2006-09-11 Wyeth Corp Heterocyclylalkylindol- eller -azaindolforbindelser som 5-hydroxytryptamin-6-ligander
US7135479B2 (en) 2002-09-12 2006-11-14 Wyeth Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans
ES2602503T3 (es) * 2010-04-22 2017-02-21 Intra-Cellular Therapies, Inc. Compuestos orgánicos
IN2014DN08562A (zh) 2012-04-14 2015-05-22 Intra Cellular Therapies Inc
PT2968320T (pt) 2013-03-15 2021-01-28 Intra Cellular Therapies Inc Compostos orgânicos
PL3076967T3 (pl) 2013-12-03 2021-12-20 Intra-Cellular Therapies, Inc. Metody leczenia objawów rezydualnych schizofrenii
BR112016023162B1 (pt) 2014-04-04 2022-11-29 Intra-Cellular Therapies, Inc Compostos orgânicos gama-carbolinas, composições farmacêuticas compreendendo os ditos compostos e uso dos mesmos no tratamento ou na profilaxia de transtornos de sistema nervoso central
US9745300B2 (en) 2014-04-04 2017-08-29 Intra-Cellular Therapies, Inc. Organic compounds
EP3331530A4 (en) * 2015-08-03 2018-12-19 Raze Therapeutics Inc. Mthfd2 inhibitors and uses thereof
MX2018009158A (es) 2016-01-26 2018-11-19 Intra Cellular Therapies Inc Compuestos organicos.
PL3407889T3 (pl) 2016-03-25 2021-11-22 Intra-Cellular Therapies, Inc. Związki organiczne i ich zastosowanie w leczeniu lub zapobieganiu zaburzeniom ośrodkowego układu nerwowego
WO2017172795A1 (en) 2016-03-28 2017-10-05 Intra-Cellular Therapies, Inc. Novel compositions and methods
EP3525763A4 (en) 2016-10-12 2020-06-17 Intra-Cellular Therapies, Inc. AMORPHE FIXED DISPERSIONS
US10961245B2 (en) 2016-12-29 2021-03-30 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders
JP6987868B2 (ja) 2016-12-29 2022-01-05 イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. 有機化合物
CN116327770A (zh) 2017-03-24 2023-06-27 细胞内治疗公司 新组合物和方法
CN111093665A (zh) 2017-07-26 2020-05-01 细胞内治疗公司 有机化合物
US11427587B2 (en) 2017-07-26 2022-08-30 Intra-Cellular Therapies, Inc. Organic compounds
BR112021003655A2 (pt) 2018-08-31 2021-05-18 Intra-Cellular Therapies, Inc. métodos novos
EP3843739A4 (en) 2018-08-31 2022-06-01 Intra-Cellular Therapies, Inc. NEW METHODS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0429341A3 (en) * 1989-11-20 1991-11-13 Rhone-Poulenc Sante Heterocyclic derivatives, their preparation and pharmaceuticals containing them
DE10299004I2 (de) * 1990-10-15 2006-03-16 Pfizer Indolderivate
JP3140155B2 (ja) * 1992-03-09 2001-03-05 杏林製薬株式会社 N,n’−ジ置換アミド誘導体
CA2092112A1 (en) * 1992-03-23 1993-09-24 Nobuyoshi Iwata Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use

Also Published As

Publication number Publication date
BR9406206A (pt) 1996-02-06
IL109234A (en) 1998-04-05
WO1994024125A1 (en) 1994-10-27
US5834493A (en) 1998-11-10
IT1271352B (it) 1997-05-27
AU6538294A (en) 1994-11-08
IL109234A0 (en) 1994-07-31
ITMI930699A1 (it) 1994-10-08
ITMI930699A0 (it) 1993-04-08
SK119795A3 (en) 1996-04-03
SG50507A1 (en) 1998-07-20
HUT74090A (en) 1996-11-28
FI954734A0 (fi) 1995-10-05
CA2160020A1 (en) 1994-10-27
HU9502913D0 (en) 1995-11-28
CN1124960A (zh) 1996-06-19
NO953967L (no) 1995-12-05
EP0694033A1 (en) 1996-01-31
CZ283398B6 (cs) 1998-04-15
AU684276B2 (en) 1997-12-11
BG100040A (bg) 1996-03-29
NO953967D0 (no) 1995-10-05
JPH08508738A (ja) 1996-09-17
NZ265055A (en) 1996-09-25
FI954734A (fi) 1995-10-05
PL310995A1 (en) 1996-01-22
CZ260295A3 (en) 1996-01-17

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