NO953967D0 - Indolderivater som 5-HT1A og/eller 5-HT2 ligander - Google Patents

Indolderivater som 5-HT1A og/eller 5-HT2 ligander

Info

Publication number
NO953967D0
NO953967D0 NO953967A NO953967A NO953967D0 NO 953967 D0 NO953967 D0 NO 953967D0 NO 953967 A NO953967 A NO 953967A NO 953967 A NO953967 A NO 953967A NO 953967 D0 NO953967 D0 NO 953967D0
Authority
NO
Norway
Prior art keywords
ht1a
ligands
indole derivatives
indole
derivatives
Prior art date
Application number
NO953967A
Other languages
English (en)
Other versions
NO953967L (no
Inventor
Myrna Gil Quintero
Vincenzo Martino
Franco Borsini
Carlo Maria Pellegrini
Marco Turconi
Ettore Giraldo
Original Assignee
Boehringer Ingelheim Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Italia filed Critical Boehringer Ingelheim Italia
Publication of NO953967D0 publication Critical patent/NO953967D0/no
Publication of NO953967L publication Critical patent/NO953967L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
NO953967A 1993-04-08 1995-10-05 Indolderivater som 5-HT1A og/eller 5-HT2 ligander NO953967L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI930699A IT1271352B (it) 1993-04-08 1993-04-08 Derivati dell'indolo utili nel trattamento dei disturbi del sistema nervoso centrale
PCT/EP1994/001016 WO1994024125A1 (en) 1993-04-08 1994-03-31 Indole derivatives as 5-ht1a and/or 5-ht2 ligands

Publications (2)

Publication Number Publication Date
NO953967D0 true NO953967D0 (no) 1995-10-05
NO953967L NO953967L (no) 1995-12-05

Family

ID=11365694

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953967A NO953967L (no) 1993-04-08 1995-10-05 Indolderivater som 5-HT1A og/eller 5-HT2 ligander

Country Status (20)

Country Link
US (1) US5834493A (no)
EP (1) EP0694033A1 (no)
JP (1) JPH08508738A (no)
CN (1) CN1124960A (no)
AU (1) AU684276B2 (no)
BG (1) BG100040A (no)
BR (1) BR9406206A (no)
CA (1) CA2160020A1 (no)
CZ (1) CZ283398B6 (no)
FI (1) FI954734A0 (no)
HU (1) HUT74090A (no)
IL (1) IL109234A (no)
IT (1) IT1271352B (no)
NO (1) NO953967L (no)
NZ (1) NZ265055A (no)
PL (1) PL310995A1 (no)
SG (1) SG50507A1 (no)
SK (1) SK119795A3 (no)
WO (1) WO1994024125A1 (no)
ZA (1) ZA942383B (no)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9420521D0 (en) * 1994-10-12 1994-11-30 Smithkline Beecham Plc Novel compounds
ES2213897T3 (es) * 1997-05-09 2004-09-01 H. Lundbeck A/S Metodo de fabricacion de sertindol.
US6861448B2 (en) * 1998-01-14 2005-03-01 Virtual Drug Development, Inc. NAD synthetase inhibitors and uses thereof
CA2317439A1 (en) 1998-01-14 1999-07-22 Wayne J. Brouillette Methods of synthesizing and screening inhibitors of bacterial nad synthetase enzyme, compounds thereof, and methods of treating bacterial and microbial infections with inhibitors of bacterial nad synthetase enzyme
US6673827B1 (en) 1999-06-29 2004-01-06 The Uab Research Foundation Methods of treating fungal infections with inhibitors of NAD synthetase enzyme
US6133287A (en) * 1998-03-24 2000-10-17 Allelix Biopharmaceuticals Inc. Piperidine-indole compounds having 5-HT6 affinity
PT1068184E (pt) * 1998-04-08 2002-12-31 Wyeth Corp Derivados n-ariloxietilamina para o tratamento de depressao
WO1999055697A1 (en) * 1998-04-29 1999-11-04 American Home Products Corporation Serotonergic agents
FR2799463B1 (fr) * 1999-10-12 2004-04-16 Adir Nouveaux composes cyano-indoles inhibiteurs de recapture de serotonine, leur procede de preparation et ces compositions pharmaceutiques qui les contiennent
DE19951360A1 (de) * 1999-10-26 2001-05-03 Aventis Pharma Gmbh Substituierte Indole
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
MXPA03005433A (es) 2000-12-22 2003-09-10 Wyeth Corp Compuestos de heterociclilalquilindol o-azaindol como ligandos de 5-hidroxitriptamina-6.
US7135479B2 (en) 2002-09-12 2006-11-14 Wyeth Antidepressant azaheterocyclylmethyl derivatives of heterocycle-fused benzodioxans
MX339805B (es) * 2010-04-22 2016-06-10 Intra-Cellular Therapies Inc Compuestos organicos.
MX2014012374A (es) 2012-04-14 2015-04-17 Intra Cellular Therapies Inc Compuestos organicos.
EP2968320B1 (en) 2013-03-15 2020-11-11 Intra-Cellular Therapies, Inc. Organic compounds
KR102495941B1 (ko) 2013-12-03 2023-02-06 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 방법
RU2016143091A (ru) 2014-04-04 2018-05-08 Интра-Селлулар Терапиз, Инк. Органические соединения
WO2015154025A1 (en) 2014-04-04 2015-10-08 Intra-Cellular Therapies, Inc. Organic compounds
EP3331530A4 (en) * 2015-08-03 2018-12-19 Raze Therapeutics Inc. Mthfd2 inhibitors and uses thereof
AU2017211791B2 (en) 2016-01-26 2022-01-06 Intra-Cellular Therapies, Inc. Organic compounds
DK3407889T3 (da) 2016-03-25 2021-08-09 Intra Cellular Therapies Inc Organiske forbindelser og deres anvendelse til behandling og forebyggelse af lidelser i centralnervesystemet
US10682354B2 (en) 2016-03-28 2020-06-16 Intra-Cellular Therapies, Inc. Compositions and methods
US11331316B2 (en) 2016-10-12 2022-05-17 Intra-Cellular Therapies, Inc. Amorphous solid dispersions
JP6987868B2 (ja) 2016-12-29 2022-01-05 イントラ−セルラー・セラピーズ・インコーポレイテッドIntra−Cellular Therapies, Inc. 有機化合物
US10961245B2 (en) 2016-12-29 2021-03-30 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders
WO2018175969A1 (en) 2017-03-24 2018-09-27 Intra-Cellular Therapies, Inc. Novel compositions and methods
JP7223742B2 (ja) 2017-07-26 2023-02-16 イントラ－セルラー・セラピーズ・インコーポレイテッド 有機化合物
WO2019023063A1 (en) 2017-07-26 2019-01-31 Intra-Cellular Therapies, Inc. ORGANIC COMPOUNDS
EP3843738A4 (en) 2018-08-31 2022-06-01 Intra-Cellular Therapies, Inc. NEW METHODS
EP3843739A4 (en) 2018-08-31 2022-06-01 Intra-Cellular Therapies, Inc. NEW METHODS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0429341A3 (en) * 1989-11-20 1991-11-13 Rhone-Poulenc Sante Heterocyclic derivatives, their preparation and pharmaceuticals containing them
WO1992006973A1 (en) * 1990-10-15 1992-04-30 Pfizer Inc. Indole derivatives
JP3140155B2 (ja) * 1992-03-09 2001-03-05 杏林製薬株式会社 Ｎ，ｎ’−ジ置換アミド誘導体
CA2092112A1 (en) * 1992-03-23 1993-09-24 Nobuyoshi Iwata Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use

Also Published As

Publication number Publication date
CA2160020A1 (en) 1994-10-27
ITMI930699A1 (it) 1994-10-08
BG100040A (bg) 1996-03-29
BR9406206A (pt) 1996-02-06
CZ283398B6 (cs) 1998-04-15
NO953967L (no) 1995-12-05
SK119795A3 (en) 1996-04-03
FI954734A (fi) 1995-10-05
ZA942383B (en) 1995-10-09
US5834493A (en) 1998-11-10
IL109234A0 (en) 1994-07-31
WO1994024125A1 (en) 1994-10-27
IT1271352B (it) 1997-05-27
PL310995A1 (en) 1996-01-22
HUT74090A (en) 1996-11-28
EP0694033A1 (en) 1996-01-31
FI954734A0 (fi) 1995-10-05
HU9502913D0 (en) 1995-11-28
JPH08508738A (ja) 1996-09-17
AU684276B2 (en) 1997-12-11
NZ265055A (en) 1996-09-25
AU6538294A (en) 1994-11-08
CN1124960A (zh) 1996-06-19
IL109234A (en) 1998-04-05
ITMI930699A0 (it) 1993-04-08
SG50507A1 (en) 1998-07-20
CZ260295A3 (en) 1996-01-17

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