ZA935541B - Polyazamacrocyclic compounds for complexation of metl ions - Google Patents
Polyazamacrocyclic compounds for complexation of metl ionsInfo
- Publication number
- ZA935541B ZA935541B ZA935541A ZA935541A ZA935541B ZA 935541 B ZA935541 B ZA 935541B ZA 935541 A ZA935541 A ZA 935541A ZA 935541 A ZA935541 A ZA 935541A ZA 935541 B ZA935541 B ZA 935541B
- Authority
- ZA
- South Africa
- Prior art keywords
- metl
- complexation
- ions
- polyazamacrocyclic compounds
- magnetic resonance
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 101100456896 Drosophila melanogaster metl gene Proteins 0.000 title 1
- 238000010668 complexation reaction Methods 0.000 title 1
- 150000002500 ions Chemical class 0.000 title 1
- 238000005481 NMR spectroscopy Methods 0.000 abstract 2
- 229910052747 lanthanoid Inorganic materials 0.000 abstract 2
- 150000002602 lanthanoids Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000005298 paramagnetic effect Effects 0.000 abstract 2
- 101100113507 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) cnh-1 gene Proteins 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
- C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Catalysts (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/662,075 US4639365A (en) | 1984-10-18 | 1984-10-18 | Gadolinium chelates as NMR contrast agents |
| US07/923,715 US5362476A (en) | 1984-10-18 | 1992-07-31 | Alkyl phosphonate polyazamacrocyclic cheates for MRI |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA935541B true ZA935541B (en) | 1994-02-24 |
Family
ID=34922820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA935541A ZA935541B (en) | 1984-10-18 | 1993-07-30 | Polyazamacrocyclic compounds for complexation of metl ions |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US5362476A (no) |
| EP (2) | EP0652885B1 (no) |
| JP (1) | JP3411919B2 (no) |
| CN (1) | CN1040750C (no) |
| AT (2) | ATE169827T1 (no) |
| AU (1) | AU4654893A (no) |
| CA (1) | CA2140557A1 (no) |
| DE (2) | DE69331203T2 (no) |
| DK (1) | DK0855401T3 (no) |
| ES (1) | ES2167667T3 (no) |
| FI (1) | FI950397A0 (no) |
| HU (1) | HUT70447A (no) |
| IL (1) | IL106164A0 (no) |
| MX (1) | MX9304624A (no) |
| NO (1) | NO306466B1 (no) |
| PH (1) | PH30934A (no) |
| PT (1) | PT855401E (no) |
| WO (1) | WO1994003464A1 (no) |
| ZA (1) | ZA935541B (no) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5714604A (en) * | 1993-05-06 | 1998-02-03 | The Dow Chemical Company | Process for the preparation of azamacrocyclic or acyclic aminophosphonate ester derivatives |
| US7186688B1 (en) | 1994-03-08 | 2007-03-06 | Human Genome Sciences, Inc. | Methods of stimulating angiogenesis in a patient by administering vascular endothelial growth factor 2 |
| AU703340B2 (en) | 1995-06-26 | 1999-03-25 | Chelator Llc | Compounds with chelation affinity and selectivity for first transition series elements, and their use in medical therapy and diagnosis |
| US5834456A (en) * | 1996-02-23 | 1998-11-10 | The Dow Chemical Company | Polyazamacrocyclofluoromonoalkylphosphonic acids, and their complexes, for use as contrast agents |
| US5952732A (en) * | 1997-11-10 | 1999-09-14 | Scarpitti; Ernest A | Vehicle security system |
| DE60006587T2 (de) * | 1999-09-13 | 2004-09-16 | Bristol-Myers Squibb Pharma Co. | Makrozyclische liganden für metallpharmazeutika |
| US6685914B1 (en) | 1999-09-13 | 2004-02-03 | Bristol-Myers Squibb Pharma Company | Macrocyclic chelants for metallopharmaceuticals |
| EP1362861B1 (en) * | 1999-09-13 | 2005-12-14 | Bristol-Myers Squibb Pharma Company | Macrocyclic chelants for metallopharmaceuticals |
| US6565828B2 (en) * | 2000-04-07 | 2003-05-20 | Bristol-Myers Squibb Company | Macrocyclic chelants for metallopharmaceuticals |
| AU8475301A (en) * | 2000-08-07 | 2002-02-18 | Univ Vanderbilt | Detection of cox-2 activity and anandamide metabolites |
| US7048907B2 (en) * | 2001-02-05 | 2006-05-23 | Biophysics Assay Laboratory, Inc. | Synthesis, compositions and methods for the measurement of the concentration of stable-isotope labeled compounds in life forms and life form excretory products |
| EP1429783A4 (en) * | 2001-09-04 | 2006-08-09 | Univ Texas Tech | MULTIMODAL IMAGING CHELATES FOR MULTIPLE USES |
| US20030133872A1 (en) * | 2001-10-22 | 2003-07-17 | Kiefer Garry E. | Radiopharmaceutical agent for the treatment of early stage cancer |
| EP1481268A4 (en) * | 2002-02-07 | 2005-06-29 | Covalent Partners Llc | NANOFILM AND MEMBRANE COMPOSITIONS |
| US20040034223A1 (en) * | 2002-02-07 | 2004-02-19 | Covalent Partners, Llc. | Amphiphilic molecular modules and constructs based thereon |
| US20040106741A1 (en) * | 2002-09-17 | 2004-06-03 | Kriesel Joshua W. | Nanofilm compositions with polymeric components |
| EP1778699A4 (en) * | 2004-08-10 | 2009-02-25 | Dow Global Technologies Inc | TARGETING OF CHELANTS AND CHELATES |
| JP5345945B2 (ja) | 2006-12-11 | 2013-11-20 | ブラッコ・イメージング・ソシエタ・ペル・アチオニ | フィブリン結合ペプチドおよびそのコンジュゲート |
| EP2476703A1 (en) | 2011-01-14 | 2012-07-18 | Bracco Imaging S.p.A | Human antibodies cross-reacting with a bacterial and a self antigen from atherosclerotic plaques |
| US7595699B1 (en) * | 2008-03-04 | 2009-09-29 | Freescale Semiconductor, Inc. | Look loop circuit and method having improved lock time |
| EP2147684A1 (en) | 2008-07-22 | 2010-01-27 | Bracco Imaging S.p.A | Diagnostic Agents Selective Against Metalloproteases |
| BR112013000236B1 (pt) * | 2010-07-06 | 2018-11-13 | Catexel Limited | método de produzir um composto, e, sal protonado |
| WO2012095516A1 (en) | 2011-01-14 | 2012-07-19 | Bracco Imaging Spa | Human antibodies cross-reacting with a bacterial and a self antigen from atherosclerotic plaques |
| JP6991148B2 (ja) | 2016-02-09 | 2022-01-12 | ブラッコ・スイス・ソシエテ・アノニム | セレクチン標的化のための組み換えキメラタンパク質 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3932451A (en) * | 1973-11-27 | 1976-01-13 | E. I. Du Pont De Nemours & Company | 1,4,7,10-Tetraazatetracyclo[5.5.1.04,13.010,13 ]tridecane and its conjugate acids |
| US3930867A (en) * | 1974-01-07 | 1976-01-06 | E. I. Du Pont De Nemours And Company | Macrocyclic polyamines as sensitizers for silver halide emulsions |
| US3996276A (en) * | 1975-08-22 | 1976-12-07 | E. I. Du Pont De Nemours And Company | Bicyclic and tricyclic phosphorous triamides |
| US3987128A (en) * | 1975-08-22 | 1976-10-19 | E. I. Du Pont De Nemours And Company | Tetracyclic tetraamino phosphoranes and method of preparation |
| US4038312A (en) * | 1975-08-22 | 1977-07-26 | E. I. Du Pont De Nemours And Company | Tricyclic phosphorous triamides |
| US4085106A (en) * | 1976-01-07 | 1978-04-18 | E. I. Du Pont De Nemours And Company | Bicyclic and tricyclic trisaminomethanes |
| GB1529150A (en) * | 1977-05-17 | 1978-10-18 | Tabushi I | Alkyl substituted cyclic alkyltetramines |
| US4337154A (en) * | 1979-04-04 | 1982-06-29 | Nippon Shokubai Kagaku Kogyo Co., Ltd. | Crosslinked composite semipermeable membrane |
| US4432907A (en) * | 1979-09-10 | 1984-02-21 | Analytical Radiation Corporation | Diamine acid fluorescent chelates |
| US4352751A (en) * | 1979-09-10 | 1982-10-05 | Analytical Radiation Corporation | Species-linked diamine triacetic acids and their chelates |
| US4957939A (en) * | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
| DE3129906C3 (de) * | 1981-07-24 | 1996-12-19 | Schering Ag | Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik |
| US4647447A (en) * | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
| US4472509A (en) * | 1982-06-07 | 1984-09-18 | Gansow Otto A | Metal chelate conjugated monoclonal antibodies |
| US4421671A (en) * | 1982-06-18 | 1983-12-20 | General Electric Company | Rare-earth-doped yttria-gadolinia ceramic scintillators |
| SU1081169A1 (ru) * | 1982-12-13 | 1984-03-23 | Ордена Ленина институт элементоорганических соединений им.А.Н.Несмеянова | @ , @ , @ -Трис(диоксифосфорилметил)-1,4,7-триазациклононан в качестве комплексона дл селективного св зывани катионов магни ,цинка,меди,никел |
| US4731239A (en) * | 1983-01-10 | 1988-03-15 | Gordon Robert T | Method for enhancing NMR imaging; and diagnostic use |
| NL194579C (nl) * | 1983-01-21 | 2002-08-05 | Schering Ag | Diagnostisch middel. |
| US4735796A (en) * | 1983-12-08 | 1988-04-05 | Gordon Robert T | Ferromagnetic, diamagnetic or paramagnetic particles useful in the diagnosis and treatment of disease |
| US4775522A (en) * | 1983-03-04 | 1988-10-04 | Children's Hospital Research Foundation, A Division Of Children's Hospital Medical Center | NMR compositions for indirectly detecting a dissolved gas in an animal |
| US5342606A (en) * | 1984-10-18 | 1994-08-30 | Board Of Regents, The University Of Texas System | Polyazamacrocyclic compounds for complexation of metal ions |
| CA1317937C (en) * | 1984-10-18 | 1993-05-18 | A. Dean Sherry | Gadolinium chelates with carboxymethyl derivatives of polyazamacrocycles as nmr contrast agents |
| US4639365A (en) * | 1984-10-18 | 1987-01-27 | The Board Of Regents, The University Of Texas System | Gadolinium chelates as NMR contrast agents |
| US4885363A (en) * | 1987-04-24 | 1989-12-05 | E. R. Squibb & Sons, Inc. | 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
| DE3772785D1 (de) * | 1986-01-23 | 1991-10-17 | Squibb & Sons Inc | 1-substituiertes-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecan und analoga. |
| FR2614020B1 (fr) * | 1987-04-14 | 1989-07-28 | Guerbet Sa | Nouveaux ligands cycliques azotes, complexes metalliques formes par ces ligands, compositions de diagnostic contenant ces complexes et procede de preparation des ligands. |
| US4889931A (en) * | 1988-09-27 | 1989-12-26 | Salutar, Inc. | Manganese (II) chelate manufacture |
| WO1990007261A2 (en) * | 1988-12-22 | 1990-07-12 | The Dow Chemical Company | Process for preparing mono-n-alkylated polyazamacrocycles |
| GB8903023D0 (en) * | 1989-02-10 | 1989-03-30 | Parker David | Chemical compounds |
| GB8914543D0 (en) * | 1989-06-23 | 1989-08-09 | Parker David | Chemical compounds |
| US5236695A (en) * | 1989-11-27 | 1993-08-17 | Concat, Ltd. | MRI image enhancement of bone and related tissue using complexes of paramagnetic cations and polyphosphonate ligands |
| DE4009119A1 (de) * | 1990-03-19 | 1991-09-26 | Schering Ag | 1,4,7,10-tetraazacyclododecan-butyltriole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
| DE4035760A1 (de) * | 1990-11-08 | 1992-05-14 | Schering Ag | Mono-n-substituierte 1,4,7,10-tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
-
1992
- 1992-07-31 US US07/923,715 patent/US5362476A/en not_active Expired - Fee Related
-
1993
- 1993-06-28 AT AT93916827T patent/ATE169827T1/de not_active IP Right Cessation
- 1993-06-28 DK DK97120436T patent/DK0855401T3/da active
- 1993-06-28 AT AT97120436T patent/ATE209211T1/de not_active IP Right Cessation
- 1993-06-28 HU HU9500283A patent/HUT70447A/hu unknown
- 1993-06-28 WO PCT/US1993/006158 patent/WO1994003464A1/en active IP Right Grant
- 1993-06-28 EP EP93916827A patent/EP0652885B1/en not_active Expired - Lifetime
- 1993-06-28 EP EP97120436A patent/EP0855401B1/en not_active Expired - Lifetime
- 1993-06-28 DE DE69331203T patent/DE69331203T2/de not_active Expired - Fee Related
- 1993-06-28 CA CA002140557A patent/CA2140557A1/en not_active Abandoned
- 1993-06-28 ES ES97120436T patent/ES2167667T3/es not_active Expired - Lifetime
- 1993-06-28 DE DE69320481T patent/DE69320481T2/de not_active Expired - Fee Related
- 1993-06-28 JP JP50529794A patent/JP3411919B2/ja not_active Expired - Fee Related
- 1993-06-28 PT PT97120436T patent/PT855401E/pt unknown
- 1993-06-28 AU AU46548/93A patent/AU4654893A/en not_active Abandoned
- 1993-06-29 IL IL106164A patent/IL106164A0/xx unknown
- 1993-07-30 ZA ZA935541A patent/ZA935541B/xx unknown
- 1993-07-30 PH PH46610A patent/PH30934A/en unknown
- 1993-07-30 CN CN93109352A patent/CN1040750C/zh not_active Expired - Fee Related
- 1993-07-30 MX MX9304624A patent/MX9304624A/es not_active IP Right Cessation
-
1994
- 1994-11-08 US US08/336,180 patent/US5630997A/en not_active Expired - Lifetime
-
1995
- 1995-01-30 FI FI950397A patent/FI950397A0/fi unknown
- 1995-01-30 NO NO950346A patent/NO306466B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1994003464A1 (en) | 1994-02-17 |
| DE69331203T2 (de) | 2002-05-08 |
| EP0652885A1 (en) | 1995-05-17 |
| US5362476A (en) | 1994-11-08 |
| DE69320481D1 (de) | 1998-09-24 |
| ATE169827T1 (de) | 1998-09-15 |
| NO306466B1 (no) | 1999-11-08 |
| EP0652885B1 (en) | 1998-08-19 |
| MX9304624A (es) | 1994-08-31 |
| US5630997A (en) | 1997-05-20 |
| CA2140557A1 (en) | 1994-02-17 |
| HUT70447A (en) | 1995-10-30 |
| ES2167667T3 (es) | 2002-05-16 |
| FI950397A (fi) | 1995-01-30 |
| DK0855401T3 (da) | 2002-05-21 |
| CN1084514A (zh) | 1994-03-30 |
| CN1040750C (zh) | 1998-11-18 |
| PH30934A (en) | 1997-12-23 |
| PT855401E (pt) | 2002-04-29 |
| EP0855401B1 (en) | 2001-11-21 |
| IL106164A0 (en) | 1993-10-20 |
| NO950346L (no) | 1995-01-30 |
| EP0855401A1 (en) | 1998-07-29 |
| DE69320481T2 (de) | 1999-03-18 |
| FI950397A0 (fi) | 1995-01-30 |
| JPH08500346A (ja) | 1996-01-16 |
| NO950346D0 (no) | 1995-01-30 |
| ATE209211T1 (de) | 2001-12-15 |
| DE69331203D1 (de) | 2002-01-03 |
| HU9500283D0 (en) | 1995-03-28 |
| AU4654893A (en) | 1994-03-03 |
| JP3411919B2 (ja) | 2003-06-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA935541B (en) | Polyazamacrocyclic compounds for complexation of metl ions | |
| IL100073A (en) | Tri- and tetraazamacrocyclic compounds and their use for complexation of metal ions | |
| DE69430730D1 (de) | Hepatobillianische magnetische resonanz-kontrastmittel | |
| GR3004576T3 (no) | ||
| DE3561816D1 (en) | Aminoethylimidazole, pharmaceutical composition containing them and process for their preparation | |
| MY109377A (en) | Polyazamacrocyclic compounds for complexation of metal ions |