ZA931724B - New derivatives of beta-amino acids - Google Patents

New derivatives of beta-amino acids

Info

Publication number
ZA931724B
ZA931724B ZA931724A ZA931724A ZA931724B ZA 931724 B ZA931724 B ZA 931724B ZA 931724 A ZA931724 A ZA 931724A ZA 931724 A ZA931724 A ZA 931724A ZA 931724 B ZA931724 B ZA 931724B
Authority
ZA
South Africa
Prior art keywords
beta
amino acids
new derivatives
derivatives
new
Prior art date
Application number
ZA931724A
Other languages
English (en)
Inventor
Georg Kottirsch
Rainer Metternich
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of ZA931724B publication Critical patent/ZA931724B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Materials For Medical Uses (AREA)
ZA931724A 1992-03-10 1993-03-10 New derivatives of beta-amino acids ZA931724B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4207544 1992-03-10

Publications (1)

Publication Number Publication Date
ZA931724B true ZA931724B (en) 1994-09-10

Family

ID=6453662

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA931724A ZA931724B (en) 1992-03-10 1993-03-10 New derivatives of beta-amino acids

Country Status (26)

Country Link
US (1) US5561112A (xx)
EP (1) EP0560730B1 (xx)
JP (1) JP2860222B2 (xx)
KR (1) KR930019690A (xx)
CN (1) CN1076200A (xx)
AT (1) ATE142618T1 (xx)
AU (1) AU659281B2 (xx)
CA (1) CA2091292A1 (xx)
CZ (1) CZ36193A3 (xx)
DE (1) DE69304573T2 (xx)
DK (1) DK0560730T3 (xx)
ES (1) ES2090934T3 (xx)
FI (1) FI931023A (xx)
GR (1) GR3021030T3 (xx)
HU (2) HUT63609A (xx)
IL (1) IL104972A (xx)
MX (1) MX9301298A (xx)
MY (1) MY109060A (xx)
NO (1) NO300778B1 (xx)
NZ (1) NZ247084A (xx)
PH (1) PH30893A (xx)
RU (1) RU2106356C1 (xx)
SG (1) SG47059A1 (xx)
SK (1) SK17093A3 (xx)
TW (1) TW256828B (xx)
ZA (1) ZA931724B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750754A (en) * 1993-03-29 1998-05-12 Zeneca Limited Heterocyclic compounds
JP3088016B2 (ja) * 1993-03-29 2000-09-18 ゼネカ・リミテッド 血小板凝集抑制剤としての複素環式化合物
US5652242A (en) * 1993-03-29 1997-07-29 Zeneca Limited Heterocyclic derivatives
US5753659A (en) * 1993-03-29 1998-05-19 Zeneca Limited Heterocyclic compouds
IL109144A (en) * 1993-03-29 2000-02-29 Zeneca Ltd Glycoprotein IIB/IIIA inhibiting 4-pyridylamino heterocyclic derivatives process for their preparation and pharmaceutical compositions containing them
DE4310643A1 (de) * 1993-04-01 1994-10-06 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
GB9313285D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Acid derivatives
GB9313268D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Chemical compounds
US5463011A (en) * 1993-06-28 1995-10-31 Zeneca Limited Acid derivatives
US5811398A (en) * 1995-04-11 1998-09-22 G. D. Searle & Co. Platelet aggregation inhibitors containing C-terminal aminergic side chain amino acid residues
US5942544A (en) * 1996-02-22 1999-08-24 Dupont Pharmaceuticals Company α-branched anilines, toluenes, and analogs thereof as factor Xa inhibitors
PT892780E (pt) * 1996-02-22 2003-02-28 Bristol Myers Squibb Pharma Co Analogos de m-amidino fenilo como inibidores do factor xa
US20050118101A1 (en) * 2002-01-28 2005-06-02 Olivier Loiseleur Beta-homolysine conjugates and their use as transport enhancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578079A (en) * 1982-08-04 1986-03-25 La Jolla Cancer Research Foundation Tetrapeptide
US4879313A (en) * 1988-07-20 1989-11-07 Mosanto Company Novel platelet-aggregation inhibitors
US5039805A (en) * 1988-12-08 1991-08-13 Hoffmann-La Roche Inc. Novel benzoic and phenylacetic acid derivatives
CA2037153A1 (en) * 1990-03-09 1991-09-10 Leo Alig Acetic acid derivatives
US5273982A (en) * 1990-03-09 1993-12-28 Hoffmann-La Roche Inc. Acetic acid derivatives
US5354738A (en) * 1992-09-04 1994-10-11 G. D. Searle & Co. Platelet aggregation inhibitors

Also Published As

Publication number Publication date
AU3406993A (en) 1993-09-16
EP0560730A2 (en) 1993-09-15
HU210878A9 (en) 1995-09-28
IL104972A0 (en) 1993-07-08
JP2860222B2 (ja) 1999-02-24
ES2090934T3 (es) 1996-10-16
CN1076200A (zh) 1993-09-15
FI931023A (fi) 1993-09-11
GR3021030T3 (en) 1996-12-31
AU659281B2 (en) 1995-05-11
EP0560730A3 (en) 1993-12-01
RU2106356C1 (ru) 1998-03-10
NZ247084A (en) 1995-09-26
ATE142618T1 (de) 1996-09-15
HUT63609A (en) 1993-09-28
MY109060A (en) 1996-11-30
US5561112A (en) 1996-10-01
NO300778B1 (no) 1997-07-21
PH30893A (en) 1997-12-23
HU9300501D0 (en) 1993-05-28
DK0560730T3 (da) 1996-10-28
SK17093A3 (en) 1993-10-06
MX9301298A (es) 1993-10-01
FI931023A0 (fi) 1993-03-08
CZ36193A3 (en) 1994-01-19
KR930019690A (ko) 1993-10-18
JPH0665175A (ja) 1994-03-08
SG47059A1 (en) 1998-03-20
CA2091292A1 (en) 1993-09-11
IL104972A (en) 1998-04-05
NO930830D0 (no) 1993-03-08
TW256828B (xx) 1995-09-11
DE69304573T2 (de) 1997-03-20
NO930830L (no) 1993-09-13
DE69304573D1 (de) 1996-10-17
EP0560730B1 (en) 1996-09-11

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