DK0560730T3 - Aminosyrederivater med antithrombotisk virkning - Google Patents

Aminosyrederivater med antithrombotisk virkning

Info

Publication number
DK0560730T3
DK0560730T3 DK93810172.2T DK93810172T DK0560730T3 DK 0560730 T3 DK0560730 T3 DK 0560730T3 DK 93810172 T DK93810172 T DK 93810172T DK 0560730 T3 DK0560730 T3 DK 0560730T3
Authority
DK
Denmark
Prior art keywords
amino acid
acid derivatives
antithrombotic effect
antithrombotic
effect
Prior art date
Application number
DK93810172.2T
Other languages
English (en)
Inventor
Georg Kottirsch
Rainer Metternich
Original Assignee
Sandoz Ltd
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd, Sandoz Ag filed Critical Sandoz Ltd
Application granted granted Critical
Publication of DK0560730T3 publication Critical patent/DK0560730T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes
DK93810172.2T 1992-03-10 1993-03-08 Aminosyrederivater med antithrombotisk virkning DK0560730T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4207544 1992-03-10

Publications (1)

Publication Number Publication Date
DK0560730T3 true DK0560730T3 (da) 1996-10-28

Family

ID=6453662

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93810172.2T DK0560730T3 (da) 1992-03-10 1993-03-08 Aminosyrederivater med antithrombotisk virkning

Country Status (26)

Country Link
US (1) US5561112A (da)
EP (1) EP0560730B1 (da)
JP (1) JP2860222B2 (da)
KR (1) KR930019690A (da)
CN (1) CN1076200A (da)
AT (1) ATE142618T1 (da)
AU (1) AU659281B2 (da)
CA (1) CA2091292A1 (da)
CZ (1) CZ36193A3 (da)
DE (1) DE69304573T2 (da)
DK (1) DK0560730T3 (da)
ES (1) ES2090934T3 (da)
FI (1) FI931023A (da)
GR (1) GR3021030T3 (da)
HU (2) HUT63609A (da)
IL (1) IL104972A (da)
MX (1) MX9301298A (da)
MY (1) MY109060A (da)
NO (1) NO300778B1 (da)
NZ (1) NZ247084A (da)
PH (1) PH30893A (da)
RU (1) RU2106356C1 (da)
SG (1) SG47059A1 (da)
SK (1) SK17093A3 (da)
TW (1) TW256828B (da)
ZA (1) ZA931724B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0690847A1 (en) * 1993-03-29 1996-01-10 Zeneca Limited Heterocyclic compounds as platelet aggregation inhibitors
US5750754A (en) * 1993-03-29 1998-05-12 Zeneca Limited Heterocyclic compounds
TW276254B (da) * 1993-03-29 1996-05-21 Zeneca Ltd
US5652242A (en) * 1993-03-29 1997-07-29 Zeneca Limited Heterocyclic derivatives
US5753659A (en) * 1993-03-29 1998-05-19 Zeneca Limited Heterocyclic compouds
DE4310643A1 (de) * 1993-04-01 1994-10-06 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
US5463011A (en) * 1993-06-28 1995-10-31 Zeneca Limited Acid derivatives
GB9313285D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Acid derivatives
GB9313268D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Chemical compounds
US5811398A (en) * 1995-04-11 1998-09-22 G. D. Searle & Co. Platelet aggregation inhibitors containing C-terminal aminergic side chain amino acid residues
US5942544A (en) * 1996-02-22 1999-08-24 Dupont Pharmaceuticals Company α-branched anilines, toluenes, and analogs thereof as factor Xa inhibitors
DK0892780T3 (da) * 1996-02-22 2003-03-03 Bristol Myers Squibb Pharma Co m-Amidinophenylanaloger som faktor Xa-inhibitorer
WO2003063910A2 (en) * 2002-01-28 2003-08-07 Novartis Ag β-HOMOLYSINE CONJUGATES AND THEIR USE AS TRANSPORT ENHANCER

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578079A (en) * 1982-08-04 1986-03-25 La Jolla Cancer Research Foundation Tetrapeptide
US4879313A (en) * 1988-07-20 1989-11-07 Mosanto Company Novel platelet-aggregation inhibitors
US5039805A (en) * 1988-12-08 1991-08-13 Hoffmann-La Roche Inc. Novel benzoic and phenylacetic acid derivatives
US5273982A (en) * 1990-03-09 1993-12-28 Hoffmann-La Roche Inc. Acetic acid derivatives
CA2037153A1 (en) * 1990-03-09 1991-09-10 Leo Alig Acetic acid derivatives
US5354738A (en) * 1992-09-04 1994-10-11 G. D. Searle & Co. Platelet aggregation inhibitors

Also Published As

Publication number Publication date
MY109060A (en) 1996-11-30
DE69304573D1 (de) 1996-10-17
HU210878A9 (en) 1995-09-28
ZA931724B (en) 1994-09-10
RU2106356C1 (ru) 1998-03-10
CA2091292A1 (en) 1993-09-11
HUT63609A (en) 1993-09-28
AU3406993A (en) 1993-09-16
KR930019690A (ko) 1993-10-18
US5561112A (en) 1996-10-01
AU659281B2 (en) 1995-05-11
NO300778B1 (no) 1997-07-21
SG47059A1 (en) 1998-03-20
EP0560730A2 (en) 1993-09-15
PH30893A (en) 1997-12-23
NO930830D0 (no) 1993-03-08
HU9300501D0 (en) 1993-05-28
TW256828B (da) 1995-09-11
IL104972A (en) 1998-04-05
MX9301298A (es) 1993-10-01
IL104972A0 (en) 1993-07-08
JPH0665175A (ja) 1994-03-08
NO930830L (no) 1993-09-13
JP2860222B2 (ja) 1999-02-24
EP0560730B1 (en) 1996-09-11
FI931023A (fi) 1993-09-11
FI931023A0 (fi) 1993-03-08
ATE142618T1 (de) 1996-09-15
NZ247084A (en) 1995-09-26
CZ36193A3 (en) 1994-01-19
SK17093A3 (en) 1993-10-06
EP0560730A3 (en) 1993-12-01
GR3021030T3 (en) 1996-12-31
ES2090934T3 (es) 1996-10-16
DE69304573T2 (de) 1997-03-20
CN1076200A (zh) 1993-09-15

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