MX9301298A - Seudopeptidos, procedimiento para su preparacion y composicion farmaceutica que los contiene. - Google Patents

Seudopeptidos, procedimiento para su preparacion y composicion farmaceutica que los contiene.

Info

Publication number
MX9301298A
MX9301298A MX9301298A MX9301298A MX9301298A MX 9301298 A MX9301298 A MX 9301298A MX 9301298 A MX9301298 A MX 9301298A MX 9301298 A MX9301298 A MX 9301298A MX 9301298 A MX9301298 A MX 9301298A
Authority
MX
Mexico
Prior art keywords
pseudopeptides
procedure
preparation
pharmaceutical composition
thrombosis
Prior art date
Application number
MX9301298A
Other languages
English (en)
Inventor
Georg Kottirsch
Rainer Metternich
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of MX9301298A publication Critical patent/MX9301298A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Abstract

Se describen seudopéptidos de la fórmula I, en forma libre o en forma de sal en donde las variable A, B, R1, X, Y, y m son como se definen en la descripción. Estos compuestos tienen actividad antitrombótica.
MX9301298A 1992-03-10 1993-03-09 Seudopeptidos, procedimiento para su preparacion y composicion farmaceutica que los contiene. MX9301298A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4207544 1992-03-10

Publications (1)

Publication Number Publication Date
MX9301298A true MX9301298A (es) 1993-10-01

Family

ID=6453662

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9301298A MX9301298A (es) 1992-03-10 1993-03-09 Seudopeptidos, procedimiento para su preparacion y composicion farmaceutica que los contiene.

Country Status (26)

Country Link
US (1) US5561112A (es)
EP (1) EP0560730B1 (es)
JP (1) JP2860222B2 (es)
KR (1) KR930019690A (es)
CN (1) CN1076200A (es)
AT (1) ATE142618T1 (es)
AU (1) AU659281B2 (es)
CA (1) CA2091292A1 (es)
CZ (1) CZ36193A3 (es)
DE (1) DE69304573T2 (es)
DK (1) DK0560730T3 (es)
ES (1) ES2090934T3 (es)
FI (1) FI931023A (es)
GR (1) GR3021030T3 (es)
HU (2) HUT63609A (es)
IL (1) IL104972A (es)
MX (1) MX9301298A (es)
MY (1) MY109060A (es)
NO (1) NO300778B1 (es)
NZ (1) NZ247084A (es)
PH (1) PH30893A (es)
RU (1) RU2106356C1 (es)
SG (1) SG47059A1 (es)
SK (1) SK17093A3 (es)
TW (1) TW256828B (es)
ZA (1) ZA931724B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750754A (en) * 1993-03-29 1998-05-12 Zeneca Limited Heterocyclic compounds
US5652242A (en) * 1993-03-29 1997-07-29 Zeneca Limited Heterocyclic derivatives
US5753659A (en) * 1993-03-29 1998-05-19 Zeneca Limited Heterocyclic compouds
WO1994022834A1 (en) * 1993-03-29 1994-10-13 Zeneca Limited Heterocyclic derivatives as platelet aggregation inhibitors
AU692439B2 (en) * 1993-03-29 1998-06-11 Zeneca Limited Heterocyclic compounds as platelet aggregation inhibitors
DE4310643A1 (de) * 1993-04-01 1994-10-06 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
US5463011A (en) * 1993-06-28 1995-10-31 Zeneca Limited Acid derivatives
GB9313285D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Acid derivatives
GB9313268D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Chemical compounds
US5811398A (en) * 1995-04-11 1998-09-22 G. D. Searle & Co. Platelet aggregation inhibitors containing C-terminal aminergic side chain amino acid residues
CA2244851A1 (en) * 1996-02-22 1997-08-28 Petrus Fredericus Wilhelmus Stouten M-amidino phenyl analogs as factor xa inhibitors
US5942544A (en) * 1996-02-22 1999-08-24 Dupont Pharmaceuticals Company α-branched anilines, toluenes, and analogs thereof as factor Xa inhibitors
JP2005526023A (ja) * 2002-01-28 2005-09-02 ノバルティス アクチエンゲゼルシャフト β−ホモリジンコンジュゲートおよび輸送エンハンサーとしてのそれらの使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578079A (en) * 1982-08-04 1986-03-25 La Jolla Cancer Research Foundation Tetrapeptide
US4879313A (en) * 1988-07-20 1989-11-07 Mosanto Company Novel platelet-aggregation inhibitors
US5039805A (en) * 1988-12-08 1991-08-13 Hoffmann-La Roche Inc. Novel benzoic and phenylacetic acid derivatives
US5273982A (en) * 1990-03-09 1993-12-28 Hoffmann-La Roche Inc. Acetic acid derivatives
CA2037153A1 (en) * 1990-03-09 1991-09-10 Leo Alig Acetic acid derivatives
US5354738A (en) * 1992-09-04 1994-10-11 G. D. Searle & Co. Platelet aggregation inhibitors

Also Published As

Publication number Publication date
IL104972A (en) 1998-04-05
NZ247084A (en) 1995-09-26
ZA931724B (en) 1994-09-10
DE69304573T2 (de) 1997-03-20
KR930019690A (ko) 1993-10-18
RU2106356C1 (ru) 1998-03-10
PH30893A (en) 1997-12-23
DE69304573D1 (de) 1996-10-17
CA2091292A1 (en) 1993-09-11
DK0560730T3 (da) 1996-10-28
NO930830L (no) 1993-09-13
JPH0665175A (ja) 1994-03-08
EP0560730A2 (en) 1993-09-15
ATE142618T1 (de) 1996-09-15
ES2090934T3 (es) 1996-10-16
IL104972A0 (en) 1993-07-08
US5561112A (en) 1996-10-01
CN1076200A (zh) 1993-09-15
TW256828B (es) 1995-09-11
GR3021030T3 (en) 1996-12-31
EP0560730B1 (en) 1996-09-11
SG47059A1 (en) 1998-03-20
HUT63609A (en) 1993-09-28
HU210878A9 (en) 1995-09-28
FI931023A0 (fi) 1993-03-08
NO930830D0 (no) 1993-03-08
NO300778B1 (no) 1997-07-21
HU9300501D0 (en) 1993-05-28
JP2860222B2 (ja) 1999-02-24
SK17093A3 (en) 1993-10-06
EP0560730A3 (en) 1993-12-01
FI931023A (fi) 1993-09-11
MY109060A (en) 1996-11-30
AU659281B2 (en) 1995-05-11
CZ36193A3 (en) 1994-01-19
AU3406993A (en) 1993-09-16

Similar Documents

Publication Publication Date Title
NZ240230A (en) Mercaptoacetylamide derivatives; preparation, use and pharmaceutical compositions thereof
NO944430D0 (no) 4-mercaptoacetylamino-[2Åbenzazepinon(3)-derivater, og anvendelse som enkefalinaseinhibitorer
ATE415394T1 (de) Zwischeprodukte zur herstellung von retroviralen protease-hemmern
GEP20074251B (en) N-oxycarbonyl substituted 5'- deoxy-5-fluorocytidines
FI920023A0 (fi) Heteroarylpiperazinfoereningar som antipsykotiska aemnen.
ES2059296T3 (es) Inhibidores de proteasas retrovirales.
DE69319976T2 (de) 7-Substituierte-9-substituierte Glycylamido-6-Demethyl-6-Deoxytetracycline
MX9101008A (es) Composicion para la fabricacion de peliculas,que contiene polihidroxiacidos y compatibilizadores y procedimiento para la preparacion de dichas peliculas
MX9301298A (es) Seudopeptidos, procedimiento para su preparacion y composicion farmaceutica que los contiene.
DE69405919T2 (de) Zusammensetzungen zur Behandlung von Keratinfasern
ATE39248T1 (de) 3-phenyltetrahydropyridin-derivate, herstellungsverfahren und verwendung in therapien.
BR9304780A (pt) Composto, processo para preparar o composto, composição farmacêutica e uso
DE69116216D1 (de) Verwendung von Squalene, Squalane oder deren Mischungen zur Herstellung einer abkühlenden Zusammensetzung zur örtlichen Behandlung von Verbrennungen
NO955093L (no) 14-substituerte marcfortiner og derivater som er anvendbare som antiparasittiske midler
FI945414A0 (fi) Menetelmä N,N-disubstituoidun aminofenolin valmistamiseksi
ATE137973T1 (de) Phospholipide zur behandlung der multiplen sklerose
FI915044A (fi) Korrosionsinhibitorer foer anvaendning i belaeggningskompositioner som innehaoller synergistiska kombinationer av kalciumborater och aminokarboxylater.
MX9203096A (es) Derivados de n-(2'-aminofenil)-benzamida, proceso para la preparacion de la misma y composiciones farmaceuticas que los contienen.

Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees