ZA925764B - Process for preparing virus-inactivated immunglobulin solutions - Google Patents
Process for preparing virus-inactivated immunglobulin solutionsInfo
- Publication number
- ZA925764B ZA925764B ZA925764A ZA925764A ZA925764B ZA 925764 B ZA925764 B ZA 925764B ZA 925764 A ZA925764 A ZA 925764A ZA 925764 A ZA925764 A ZA 925764A ZA 925764 B ZA925764 B ZA 925764B
- Authority
- ZA
- South Africa
- Prior art keywords
- inactivated
- solutions
- immunglobulin
- preparing virus
- virus
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 108060003951 Immunoglobulin Proteins 0.000 abstract 2
- 102000018358 immunoglobulin Human genes 0.000 abstract 2
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 238000002414 normal-phase solid-phase extraction Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0017—Filtration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4125625A DE4125625C2 (de) | 1991-08-02 | 1991-08-02 | Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA925764B true ZA925764B (en) | 1993-04-28 |
Family
ID=6437560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA925764A ZA925764B (en) | 1991-08-02 | 1992-07-31 | Process for preparing virus-inactivated immunglobulin solutions |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5648472A (cs) |
| EP (1) | EP0525502B2 (cs) |
| JP (1) | JP2969310B2 (cs) |
| KR (1) | KR100188448B1 (cs) |
| AT (1) | ATE143812T1 (cs) |
| CZ (1) | CZ291813B6 (cs) |
| DE (2) | DE4125625C2 (cs) |
| DK (1) | DK0525502T4 (cs) |
| ES (1) | ES2092604T5 (cs) |
| FI (1) | FI107122B (cs) |
| IL (1) | IL102525A (cs) |
| SK (1) | SK280680B6 (cs) |
| YU (1) | YU48242B (cs) |
| ZA (1) | ZA925764B (cs) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4424935C1 (de) * | 1994-07-14 | 1996-03-21 | Immuno Ag | Humanes virussicheres monomeres Immunglobulin A und Verfahren zu seiner Herstellung |
| US6136865A (en) * | 1995-05-20 | 2000-10-24 | Octapharma Ag | Method for reduction of the infectiousness of potentially infectious material |
| AT403477B (de) * | 1996-04-30 | 1998-02-25 | Immuno Ag | Biologisches material frei von viralen und molekularen pathogenen und verfahren zur herstellung |
| IL121900A (en) * | 1997-10-07 | 2001-12-23 | Omrix Biopharmaceuticals Ltd | A method for the purification of immunoglobulins |
| PT911037E (pt) † | 1997-10-23 | 2002-12-31 | Mitsubishi Pharma Corp | Preparacao de imunoglobulina armazenavel a temperatura ambiente para injeccao intravenosa |
| DE10016877A1 (de) * | 2000-04-05 | 2001-10-18 | Scintec Diagnostics Gmbh Zug | (Glyko-)Proteine mit hoher Immunreaktivität sowie ein Verfahren zu ihrer Herstellung |
| IL136552A (en) | 2000-06-05 | 2005-05-17 | Omrix Biopharmaceuticals Ltd | Method for the inactivation of viruses by a solvent - detergent combination and by nanofiltration |
| US6893639B2 (en) * | 2001-10-19 | 2005-05-17 | Hemacare Corporation | Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates |
| US8541399B2 (en) | 2002-02-19 | 2013-09-24 | Resolution Chemicals Limited | Solvent-based sterilisation of pharmaceuticals |
| ATE428730T1 (de) * | 2003-08-12 | 2009-05-15 | Octapharma Ag | Verfahren zur herstellung einer alpha-1- antitrypsinlösung |
| US6881573B2 (en) * | 2003-09-12 | 2005-04-19 | Allan L. Louderback | Augmented solvent/detergent method for inactivating enveloped and non-enveloped viruses |
| US20060234907A1 (en) * | 2004-02-13 | 2006-10-19 | Werner Gehringer | Albumin solution and process for the production thereof |
| EP1718675B2 (en) | 2004-02-27 | 2017-01-25 | Octapharma AG | A method of providing a purified, virus safe antibody preparation |
| RU2352358C1 (ru) * | 2007-10-04 | 2009-04-20 | Наталия Васильевна Зубкова | Способ приготовления вирусинактивированных растворов иммуноглобулинов |
| FR2944281B1 (fr) * | 2009-04-08 | 2011-07-29 | Fabre Pierre Dermo Cosmetique | Derives soufres de resorcinol, leur preparation et leurs utilisations cosmetiques |
| CN111108193A (zh) | 2017-09-18 | 2020-05-05 | 拜耳医药保健有限公司 | 使用n-甲基葡糖酰胺及其衍生物灭活病毒的方法 |
| MX2020004151A (es) | 2017-10-30 | 2020-08-13 | Takeda Pharmaceuticals Co | Detergentes compatibles con el medio ambiente para la inactivacion de virus envueltos en lipidos. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57140724A (en) * | 1981-02-25 | 1982-08-31 | Green Cross Corp:The | Heat-treatment of aqueous solution containing cold insoluble globulin |
| US4396608A (en) * | 1981-08-24 | 1983-08-02 | Cutter Laboratories | Intravenously injectable immune serum globulin |
| US4481189A (en) * | 1982-04-14 | 1984-11-06 | New York Blood Center Inc. | Process for preparing sterilized plasma and plasma derivatives |
| US4540573A (en) * | 1983-07-14 | 1985-09-10 | New York Blood Center, Inc. | Undenatured virus-free biologically active protein derivatives |
| US4789545A (en) * | 1986-03-31 | 1988-12-06 | New York Blood Center, Inc. | Removal of lipid soluble process chemicals from biological materials by extraction with naturally occurring oils or synthetic substitutes thereof |
| US4909940A (en) * | 1987-12-30 | 1990-03-20 | New York Blood Center, Inc. | Extraction of process chemicals from labile biological mixtures with organic alcohols or with halogenated hydrocarbons |
| US5094960A (en) * | 1988-10-07 | 1992-03-10 | New York Blood Center, Inc. | Removal of process chemicals from labile biological mixtures by hydrophobic interaction chromatography |
-
1991
- 1991-08-02 DE DE4125625A patent/DE4125625C2/de not_active Expired - Lifetime
-
1992
- 1992-07-14 DK DK92111947T patent/DK0525502T4/da active
- 1992-07-14 AT AT92111947T patent/ATE143812T1/de active
- 1992-07-14 ES ES92111947T patent/ES2092604T5/es not_active Expired - Lifetime
- 1992-07-14 EP EP92111947A patent/EP0525502B2/de not_active Expired - Lifetime
- 1992-07-14 DE DE59207324T patent/DE59207324D1/de not_active Expired - Lifetime
- 1992-07-16 IL IL10252592A patent/IL102525A/xx not_active IP Right Cessation
- 1992-07-29 SK SK2369-92A patent/SK280680B6/sk not_active IP Right Cessation
- 1992-07-29 FI FI923425A patent/FI107122B/fi active
- 1992-07-29 YU YU74092A patent/YU48242B/sh unknown
- 1992-07-29 CZ CS19922369A patent/CZ291813B6/cs not_active IP Right Cessation
- 1992-07-30 JP JP4224884A patent/JP2969310B2/ja not_active Expired - Lifetime
- 1992-07-31 ZA ZA925764A patent/ZA925764B/xx unknown
- 1992-08-01 KR KR1019920013901A patent/KR100188448B1/ko not_active Expired - Lifetime
-
1994
- 1994-10-26 US US08/329,684 patent/US5648472A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| SK236992A3 (en) | 1995-01-12 |
| DE59207324D1 (de) | 1996-11-14 |
| EP0525502A1 (de) | 1993-02-03 |
| EP0525502B2 (de) | 2005-08-10 |
| CZ291813B6 (cs) | 2003-06-18 |
| JP2969310B2 (ja) | 1999-11-02 |
| ATE143812T1 (de) | 1996-10-15 |
| FI107122B (fi) | 2001-06-15 |
| US5648472A (en) | 1997-07-15 |
| DK0525502T4 (da) | 2005-09-19 |
| DE4125625A1 (de) | 1993-02-04 |
| SK280680B6 (sk) | 2000-06-12 |
| CZ236992A3 (en) | 1993-02-17 |
| EP0525502B1 (de) | 1996-10-09 |
| IL102525A (en) | 2005-05-17 |
| YU74092A (sh) | 1995-10-24 |
| DK0525502T3 (da) | 1997-03-17 |
| ES2092604T3 (es) | 1996-12-01 |
| ES2092604T5 (es) | 2006-03-01 |
| YU48242B (sh) | 1997-08-22 |
| IL102525A0 (en) | 1993-01-14 |
| DE4125625C2 (de) | 1999-12-02 |
| FI923425L (fi) | 1993-02-03 |
| FI923425A0 (fi) | 1992-07-29 |
| JPH05202100A (ja) | 1993-08-10 |
| KR930004329A (ko) | 1993-03-22 |
| KR100188448B1 (ko) | 1999-06-01 |
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