ES2092604T3 - Procedimiento para la preparacion de soluciones de inmunoglobulina inactivadas con virus. - Google Patents

Procedimiento para la preparacion de soluciones de inmunoglobulina inactivadas con virus.

Info

Publication number
ES2092604T3
ES2092604T3 ES92111947T ES92111947T ES2092604T3 ES 2092604 T3 ES2092604 T3 ES 2092604T3 ES 92111947 T ES92111947 T ES 92111947T ES 92111947 T ES92111947 T ES 92111947T ES 2092604 T3 ES2092604 T3 ES 2092604T3
Authority
ES
Spain
Prior art keywords
virus
preparation
procedure
immunoglobulin solutions
inactivated immunoglobulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92111947T
Other languages
English (en)
Other versions
ES2092604T5 (es
Inventor
Werner Gehringer
Patrick Selosse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Octapharma AG
Original Assignee
Octapharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6437560&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2092604(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Octapharma AG filed Critical Octapharma AG
Application granted granted Critical
Publication of ES2092604T3 publication Critical patent/ES2092604T3/es
Publication of ES2092604T5 publication Critical patent/ES2092604T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0017—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LA PRESENTE INVENCION DESCRIBE UN PROCEDIMIENTO PARA LA PRODUCCION DE SOLUCIONES DE INMUNOGLOBULINA CON VIRUS INACTIVADOS APROPIADAS PARA LA APLICACION INTRAVENOSA, QUE SE CARACTERIZA POR EL HECHO DE QUE LA INMUNOGLOBINA ES TRATADA CON AGENTES TENSIOACTIVOS NO IONICOS QUE SE ELIMINAN SEGUIDAMENTE POR EXTRACCION DE FASE SOLIDA EN MATERIALES HIDROFOBOS.
ES92111947T 1991-08-02 1992-07-14 Procedimiento para la preparacion de soluciones de inmunoglobulina inactivadas con virus. Expired - Lifetime ES2092604T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4125625 1991-08-02
DE4125625A DE4125625C2 (de) 1991-08-02 1991-08-02 Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen

Publications (2)

Publication Number Publication Date
ES2092604T3 true ES2092604T3 (es) 1996-12-01
ES2092604T5 ES2092604T5 (es) 2006-03-01

Family

ID=6437560

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92111947T Expired - Lifetime ES2092604T5 (es) 1991-08-02 1992-07-14 Procedimiento para la preparacion de soluciones de inmunoglobulina inactivadas con virus.

Country Status (14)

Country Link
US (1) US5648472A (es)
EP (1) EP0525502B2 (es)
JP (1) JP2969310B2 (es)
KR (1) KR100188448B1 (es)
AT (1) ATE143812T1 (es)
CZ (1) CZ291813B6 (es)
DE (2) DE4125625C2 (es)
DK (1) DK0525502T4 (es)
ES (1) ES2092604T5 (es)
FI (1) FI107122B (es)
IL (1) IL102525A (es)
SK (1) SK280680B6 (es)
YU (1) YU48242B (es)
ZA (1) ZA925764B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4424935C1 (de) * 1994-07-14 1996-03-21 Immuno Ag Humanes virussicheres monomeres Immunglobulin A und Verfahren zu seiner Herstellung
US6136865A (en) * 1995-05-20 2000-10-24 Octapharma Ag Method for reduction of the infectiousness of potentially infectious material
AT403477B (de) * 1996-04-30 1998-02-25 Immuno Ag Biologisches material frei von viralen und molekularen pathogenen und verfahren zur herstellung
IL121900A (en) * 1997-10-07 2001-12-23 Omrix Biopharmaceuticals Ltd A method for the purification of immunoglobulins
US6159471A (en) † 1997-10-23 2000-12-12 Yoshitomi Pharmaceutical Industries, Ltd. Room temperature storable immunoglobulin preparation for intravenous injection
DE10016877A1 (de) * 2000-04-05 2001-10-18 Scintec Diagnostics Gmbh Zug (Glyko-)Proteine mit hoher Immunreaktivität sowie ein Verfahren zu ihrer Herstellung
IL136552A (en) 2000-06-05 2005-05-17 Omrix Biopharmaceuticals Ltd Method for the inactivation of viruses by a solvent - detergent combination and by nanofiltration
US6893639B2 (en) * 2001-10-19 2005-05-17 Hemacare Corporation Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates
WO2003070285A1 (en) 2002-02-19 2003-08-28 Resolution Chemicals Limited Solvent-based sterilisation of pharmaceuticals
BRPI0412835A (pt) * 2003-08-12 2006-09-26 Octapharma Ag processo para preparação de uma solução de alfa-1-antitripsina
US6881573B2 (en) * 2003-09-12 2005-04-19 Allan L. Louderback Augmented solvent/detergent method for inactivating enveloped and non-enveloped viruses
US20060234907A1 (en) * 2004-02-13 2006-10-19 Werner Gehringer Albumin solution and process for the production thereof
UA87836C2 (ru) 2004-02-27 2009-08-25 Октафарма Аг Способ получения очищенных, безопасных с вирусологической точки зрения препаратов антител
FR2944281B1 (fr) * 2009-04-08 2011-07-29 Fabre Pierre Dermo Cosmetique Derives soufres de resorcinol, leur preparation et leurs utilisations cosmetiques
TWI834623B (zh) 2017-09-18 2024-03-11 美商拜耳保健有限責任公司 使用n-甲基葡糖醯胺及其衍生物以使病毒去活化之方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57140724A (en) * 1981-02-25 1982-08-31 Green Cross Corp:The Heat-treatment of aqueous solution containing cold insoluble globulin
US4396608A (en) * 1981-08-24 1983-08-02 Cutter Laboratories Intravenously injectable immune serum globulin
US4481189A (en) * 1982-04-14 1984-11-06 New York Blood Center Inc. Process for preparing sterilized plasma and plasma derivatives
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
US4789545A (en) * 1986-03-31 1988-12-06 New York Blood Center, Inc. Removal of lipid soluble process chemicals from biological materials by extraction with naturally occurring oils or synthetic substitutes thereof
US4909940A (en) * 1987-12-30 1990-03-20 New York Blood Center, Inc. Extraction of process chemicals from labile biological mixtures with organic alcohols or with halogenated hydrocarbons
US5094960A (en) * 1988-10-07 1992-03-10 New York Blood Center, Inc. Removal of process chemicals from labile biological mixtures by hydrophobic interaction chromatography

Also Published As

Publication number Publication date
DK0525502T3 (da) 1997-03-17
JP2969310B2 (ja) 1999-11-02
FI923425A (fi) 1993-02-03
DK0525502T4 (da) 2005-09-19
ES2092604T5 (es) 2006-03-01
CZ291813B6 (cs) 2003-06-18
FI107122B (fi) 2001-06-15
EP0525502A1 (de) 1993-02-03
US5648472A (en) 1997-07-15
CZ236992A3 (en) 1993-02-17
ZA925764B (en) 1993-04-28
EP0525502B2 (de) 2005-08-10
ATE143812T1 (de) 1996-10-15
DE59207324D1 (de) 1996-11-14
SK236992A3 (en) 1995-01-05
IL102525A (en) 2005-05-17
IL102525A0 (en) 1993-01-14
JPH05202100A (ja) 1993-08-10
KR930004329A (ko) 1993-03-22
KR100188448B1 (ko) 1999-06-01
DE4125625A1 (de) 1993-02-04
YU74092A (sh) 1995-10-24
EP0525502B1 (de) 1996-10-09
DE4125625C2 (de) 1999-12-02
FI923425A0 (fi) 1992-07-29
YU48242B (sh) 1997-08-22
SK280680B6 (sk) 2000-06-12

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