ZA925469B - Process for chiral thiazolidine-2,4-dione hypoglycemics and intermediates - Google Patents
Process for chiral thiazolidine-2,4-dione hypoglycemics and intermediatesInfo
- Publication number
- ZA925469B ZA925469B ZA925469A ZA925469A ZA925469B ZA 925469 B ZA925469 B ZA 925469B ZA 925469 A ZA925469 A ZA 925469A ZA 925469 A ZA925469 A ZA 925469A ZA 925469 B ZA925469 B ZA 925469B
- Authority
- ZA
- South Africa
- Prior art keywords
- hypoglycemics
- dione
- intermediates
- thiazolidine
- chiral
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73356491A | 1991-07-22 | 1991-07-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA925469B true ZA925469B (en) | 1994-01-21 |
Family
ID=24948157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA925469A ZA925469B (en) | 1991-07-22 | 1992-07-21 | Process for chiral thiazolidine-2,4-dione hypoglycemics and intermediates |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5512689A (ja) |
| EP (1) | EP0595868B1 (ja) |
| JP (1) | JP2671962B2 (ja) |
| AT (1) | ATE173728T1 (ja) |
| AU (1) | AU660701B2 (ja) |
| CA (1) | CA2111445C (ja) |
| DE (1) | DE69227689T2 (ja) |
| DK (1) | DK0595868T3 (ja) |
| ES (1) | ES2123562T3 (ja) |
| FI (1) | FI940306A0 (ja) |
| HU (1) | HUT70412A (ja) |
| IE (1) | IE922359A1 (ja) |
| IL (1) | IL102574A (ja) |
| MX (1) | MX9204278A (ja) |
| MY (1) | MY131277A (ja) |
| NO (1) | NO940227L (ja) |
| NZ (1) | NZ243651A (ja) |
| PT (1) | PT100710B (ja) |
| TW (1) | TW199891B (ja) |
| WO (1) | WO1993002060A1 (ja) |
| ZA (1) | ZA925469B (ja) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU660187B2 (en) * | 1991-07-22 | 1995-06-15 | Pfizer Inc. | Chiral intermediates for the preparation of antidiabetics thiazoles |
| FR2699172B1 (fr) * | 1992-12-11 | 1995-01-20 | Adir | Nouveaux dérivés de 4-méthyl-1,3-oxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| TW416958B (en) * | 1993-05-14 | 2001-01-01 | Pfizer | Enantioselective oxazaborolidine catalysts |
| CA2383347A1 (en) * | 1999-08-31 | 2001-03-08 | Maxia Pharmaceuticals, Inc. | Benzylidene-thiazolidinediones and analogues and their use in the treatment of diabetes |
| IL157740A0 (en) | 2001-03-07 | 2004-03-28 | Incyte San Diego Inc | Heterocyclic derivatives and pharmaceutical compositions containing the same |
| US7265139B2 (en) * | 2001-03-08 | 2007-09-04 | Incyte San Diego Inc. | RXR activating molecules |
| CA2340824A1 (en) * | 2001-03-14 | 2002-09-14 | Ibm Canada Limited-Ibm Canada Limitee | Method and system for application behavior analysis |
| EP1421061A4 (en) * | 2001-08-17 | 2004-12-22 | Incyte San Diego Inc | OXIME DERIVATIVES FOR THE TREATMENT OF DYSLIPIDEMIA AND HYPERCHOLESTEROLEMIA |
| AU2002352706A1 (en) * | 2001-11-15 | 2003-06-10 | Maxia Pharmaceuticals, Inc. | N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders, cancer, and other diseases |
| US7196108B2 (en) * | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
| US7102000B2 (en) * | 2002-03-08 | 2006-09-05 | Incyte San Diego Inc. | Heterocyclic amide derivatives for the treatment of diabetes and other diseases |
| WO2004066952A2 (en) * | 2003-01-29 | 2004-08-12 | Incyte Corporation | Benzoxazole, benzothiazole, and benzimidazole derivatives for the treatment of cancer and other diseases |
| EP1643993A2 (en) * | 2003-04-18 | 2006-04-12 | Incyte San Diego Incorporated | Substituted isochroman compounds for the treatment of metabolic disorders, cancer and other diseases |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4943635A (en) * | 1987-08-27 | 1990-07-24 | President & Fellows Of Harvard College | Enantioselective reduction of ketones |
| US5036079A (en) * | 1989-12-07 | 1991-07-30 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
| TW222626B (ja) * | 1991-07-22 | 1994-04-21 | Pfizer |
-
1992
- 1992-07-01 DE DE69227689T patent/DE69227689T2/de not_active Expired - Fee Related
- 1992-07-01 JP JP5502810A patent/JP2671962B2/ja not_active Expired - Fee Related
- 1992-07-01 EP EP92915192A patent/EP0595868B1/en not_active Expired - Lifetime
- 1992-07-01 CA CA002111445A patent/CA2111445C/en not_active Expired - Fee Related
- 1992-07-01 HU HU9400188A patent/HUT70412A/hu unknown
- 1992-07-01 DK DK92915192T patent/DK0595868T3/da active
- 1992-07-01 AU AU23062/92A patent/AU660701B2/en not_active Ceased
- 1992-07-01 WO PCT/US1992/005433 patent/WO1993002060A1/en active IP Right Grant
- 1992-07-01 AT AT92915192T patent/ATE173728T1/de not_active IP Right Cessation
- 1992-07-01 ES ES92915192T patent/ES2123562T3/es not_active Expired - Lifetime
- 1992-07-07 TW TW081105396A patent/TW199891B/zh active
- 1992-07-20 PT PT100710A patent/PT100710B/pt not_active IP Right Cessation
- 1992-07-21 IE IE235992A patent/IE922359A1/en not_active IP Right Cessation
- 1992-07-21 ZA ZA925469A patent/ZA925469B/xx unknown
- 1992-07-21 MY MYPI92001294A patent/MY131277A/en unknown
- 1992-07-21 NZ NZ243651A patent/NZ243651A/en unknown
- 1992-07-21 MX MX9204278A patent/MX9204278A/es unknown
- 1992-07-21 IL IL10257492A patent/IL102574A/en not_active IP Right Cessation
-
1994
- 1994-01-21 NO NO940227A patent/NO940227L/no unknown
- 1994-01-21 FI FI940306A patent/FI940306A0/fi unknown
-
1995
- 1995-04-05 US US08/417,502 patent/US5512689A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HUT70412A (en) | 1995-10-30 |
| CA2111445A1 (en) | 1993-02-04 |
| DE69227689T2 (de) | 1999-04-22 |
| EP0595868B1 (en) | 1998-11-25 |
| CA2111445C (en) | 1997-02-18 |
| TW199891B (ja) | 1993-02-11 |
| FI940306A (fi) | 1994-01-21 |
| JP2671962B2 (ja) | 1997-11-05 |
| PT100710B (pt) | 1999-07-30 |
| AU2306292A (en) | 1993-02-23 |
| PT100710A (pt) | 1993-09-30 |
| NO940227D0 (no) | 1994-01-21 |
| IL102574A (en) | 1996-07-23 |
| HU9400188D0 (en) | 1994-05-30 |
| ATE173728T1 (de) | 1998-12-15 |
| MX9204278A (es) | 1994-03-31 |
| JPH07502017A (ja) | 1995-03-02 |
| DK0595868T3 (da) | 1999-08-09 |
| MY131277A (en) | 2007-07-31 |
| IE922359A1 (en) | 1993-01-27 |
| US5512689A (en) | 1996-04-30 |
| DE69227689D1 (de) | 1999-01-07 |
| NZ243651A (en) | 1994-01-26 |
| AU660701B2 (en) | 1995-07-06 |
| NO940227L (no) | 1994-01-21 |
| FI940306A0 (fi) | 1994-01-21 |
| ES2123562T3 (es) | 1999-01-16 |
| IL102574A0 (en) | 1993-01-14 |
| WO1993002060A1 (en) | 1993-02-04 |
| EP0595868A1 (en) | 1994-05-11 |
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