ZA923395B - The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs - Google Patents

The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs

Info

Publication number
ZA923395B
ZA923395B ZA923395A ZA923395A ZA923395B ZA 923395 B ZA923395 B ZA 923395B ZA 923395 A ZA923395 A ZA 923395A ZA 923395 A ZA923395 A ZA 923395A ZA 923395 B ZA923395 B ZA 923395B
Authority
ZA
South Africa
Prior art keywords
medetomidine
regulate
rate
optically active
drugs
Prior art date
Application number
ZA923395A
Other languages
English (en)
Inventor
Harry Gosta Jalonen
Gosta Jalonen Harry
Arto Johannes Karjalainen
Johannes Karjalainen Arto
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of ZA923395B publication Critical patent/ZA923395B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA923395A 1991-05-31 1992-05-11 The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs ZA923395B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919111732A GB9111732D0 (en) 1991-05-31 1991-05-31 The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs

Publications (1)

Publication Number Publication Date
ZA923395B true ZA923395B (en) 1993-03-31

Family

ID=10695876

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA923395A ZA923395B (en) 1991-05-31 1992-05-11 The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs

Country Status (17)

Country Link
US (1) US5438067A (et)
EP (1) EP0587819B1 (et)
JP (2) JP3483881B2 (et)
AT (1) ATE149090T1 (et)
AU (1) AU1798192A (et)
CA (1) CA2110161C (et)
DE (1) DE69217658T2 (et)
EE (1) EE03053B1 (et)
FI (1) FI104948B (et)
GB (2) GB9111732D0 (et)
IE (1) IE67168B1 (et)
LT (1) LT3130B (et)
LV (1) LV10047B (et)
NO (1) NO303818B1 (et)
NZ (1) NZ242717A (et)
WO (1) WO1992021338A1 (et)
ZA (1) ZA923395B (et)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883115A (en) * 1992-11-09 1999-03-16 Pharmetrix Division Technical Chemicals & Products, Inc. Transdermal delivery of the eutomer of a chiral drug
GB2290964A (en) * 1994-07-08 1996-01-17 Arto Olavi Urtti Transdermal drug delivery system
GB9521680D0 (en) * 1995-10-23 1996-01-03 Orion Yhtymo Oy New use of imidazole derivatives
US5730721A (en) 1996-01-25 1998-03-24 Vesture Corporation Medical applicator and method
GB9614098D0 (en) 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
IT1290255B1 (it) * 1997-02-05 1998-10-22 Wallcovering Pubblicita S R L Supporto sagomato aderente all'epidermide per la cessione di sostanze cosmetiche o farmacologiche e metodo per la sua fabbricazione
DE19936395C2 (de) 1999-08-03 2002-07-18 Antonia Buntz Kosmetikpflaster und Verfahren zum Anheben der weiblichen Brust mittels eines solchen Kosmetikpflasters und seine Verwendung
US6682757B1 (en) 2000-11-16 2004-01-27 Euro-Celtique, S.A. Titratable dosage transdermal delivery system
US7795263B2 (en) * 2008-07-08 2010-09-14 Wildlife Laboratories, Inc. Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals
KR101859486B1 (ko) * 2009-05-15 2018-06-28 레크로파마, 인코포레이티드 설하용 덱스메데토미딘 조성물과 그의 사용 방법
JP2013516482A (ja) * 2010-01-08 2013-05-13 レクロ・ファーマ，インコーポレーテッド 局所経皮用デクスメデトミジン組成物およびそれらの使用方法
US20120202863A1 (en) * 2011-02-03 2012-08-09 Gerald Horn Compositions and methods for treatment of glaucoma
AU2012352528B9 (en) 2011-12-11 2017-11-02 Baudax Bio, Inc. Intranasal dexmedetomidine compositions and methods of use thereof
US10772871B2 (en) 2013-10-07 2020-09-15 Teikoku Pharma Usa, Inc. Dexmedetomidine transdermal delivery devices and methods for using the same
TWI709417B (zh) * 2013-10-07 2020-11-11 美商帝國製藥美國股份有限公司 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物
EP3054930B1 (en) 2013-10-07 2020-12-02 Teikoku Pharma USA, Inc. Methods and compositions for transdermal delivery of a non-sedative amount of dexmedetomidine
CA2924188C (en) * 2013-10-07 2018-12-18 Teikoku Pharma Usa, Inc. Methods and compositions for managing pain comprising dexmedetomidine transdermal compositions
RU2648817C2 (ru) * 2013-10-07 2018-03-28 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Способы и композиции для лечения абстинентных синдромов с использованием неседативных трансдермальных композиций на основе дексмедетомидина
US9974754B2 (en) 2013-12-18 2018-05-22 Maruishi Pharmaceutical Co., Ltd. Hydrous adhesive patch
CN111346072B (zh) * 2018-12-21 2022-05-27 宜昌人福药业有限责任公司 一种透皮给药的药物组合物及其制备方法
US20220211672A1 (en) 2019-05-01 2022-07-07 Clexio Biosciences Ltd. Methods of treating pruritus
US11185532B2 (en) 2019-05-01 2021-11-30 Clexio Biosciences Ltd. Methods of treating pruritus
TWI772807B (zh) 2019-05-27 2022-08-01 日商救急藥品工業股份有限公司 外用製劑

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
FI864570A0 (fi) 1986-11-11 1986-11-11 Farmos Oy Terapeutiskt anvaendbar foerening.
GB2206880B (en) * 1987-07-16 1991-04-24 Farmos Oy Optical isomers of an imidazole derivative
GB2215206B (en) * 1988-02-29 1991-07-03 Farmos Oy 4-substituted imidazole derivatives useful in perioperative care
US5217718A (en) * 1989-08-18 1993-06-08 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5124157A (en) * 1989-08-18 1992-06-23 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5304569A (en) * 1989-11-13 1994-04-19 Orion-Yhtyma Oy Compositions and their use in lowering intraocular pressure

Also Published As

Publication number Publication date
JP3483881B2 (ja) 2004-01-06
ATE149090T1 (de) 1997-03-15
GB2256367B (en) 1995-03-15
JP2003327531A (ja) 2003-11-19
GB9211033D0 (en) 1992-07-08
JPH06507888A (ja) 1994-09-08
LT3130B (en) 1994-12-25
LV10047A (lv) 1994-05-10
LTIP112A (en) 1994-07-15
NZ242717A (en) 1994-03-25
WO1992021338A1 (en) 1992-12-10
FI935351A0 (fi) 1993-11-30
DE69217658T2 (de) 1997-07-03
NO303818B1 (no) 1998-09-07
GB9111732D0 (en) 1991-07-24
IE921937A1 (en) 1992-12-02
IE67168B1 (en) 1996-03-06
DE69217658D1 (de) 1997-04-03
NO934323L (no) 1993-11-29
CA2110161C (en) 2004-08-03
CA2110161A1 (en) 1992-12-10
EP0587819A1 (en) 1994-03-23
LV10047B (en) 1995-02-20
NO934323D0 (no) 1993-11-29
FI935351A (fi) 1993-11-30
FI104948B (fi) 2000-05-15
EE03053B1 (et) 1997-12-15
GB2256367A (en) 1992-12-09
US5438067A (en) 1995-08-01
EP0587819B1 (en) 1997-02-26
AU1798192A (en) 1993-01-08

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