ZA923395B - The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs - Google Patents
The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugsInfo
- Publication number
- ZA923395B ZA923395B ZA923395A ZA923395A ZA923395B ZA 923395 B ZA923395 B ZA 923395B ZA 923395 A ZA923395 A ZA 923395A ZA 923395 A ZA923395 A ZA 923395A ZA 923395 B ZA923395 B ZA 923395B
- Authority
- ZA
- South Africa
- Prior art keywords
- medetomidine
- regulate
- rate
- optically active
- drugs
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919111732A GB9111732D0 (en) | 1991-05-31 | 1991-05-31 | The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA923395B true ZA923395B (en) | 1993-03-31 |
Family
ID=10695876
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA923395A ZA923395B (en) | 1991-05-31 | 1992-05-11 | The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs |
Country Status (17)
Country | Link |
---|---|
US (1) | US5438067A (et) |
EP (1) | EP0587819B1 (et) |
JP (2) | JP3483881B2 (et) |
AT (1) | ATE149090T1 (et) |
AU (1) | AU1798192A (et) |
CA (1) | CA2110161C (et) |
DE (1) | DE69217658T2 (et) |
EE (1) | EE03053B1 (et) |
FI (1) | FI104948B (et) |
GB (2) | GB9111732D0 (et) |
IE (1) | IE67168B1 (et) |
LT (1) | LT3130B (et) |
LV (1) | LV10047B (et) |
NO (1) | NO303818B1 (et) |
NZ (1) | NZ242717A (et) |
WO (1) | WO1992021338A1 (et) |
ZA (1) | ZA923395B (et) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5883115A (en) * | 1992-11-09 | 1999-03-16 | Pharmetrix Division Technical Chemicals & Products, Inc. | Transdermal delivery of the eutomer of a chiral drug |
GB2290964A (en) * | 1994-07-08 | 1996-01-17 | Arto Olavi Urtti | Transdermal drug delivery system |
GB9521680D0 (en) * | 1995-10-23 | 1996-01-03 | Orion Yhtymo Oy | New use of imidazole derivatives |
US5730721A (en) | 1996-01-25 | 1998-03-24 | Vesture Corporation | Medical applicator and method |
GB9614098D0 (en) | 1996-07-05 | 1996-09-04 | Orion Yhtymae Oy | Transdermal delivery of levosimendan |
IT1290255B1 (it) * | 1997-02-05 | 1998-10-22 | Wallcovering Pubblicita S R L | Supporto sagomato aderente all'epidermide per la cessione di sostanze cosmetiche o farmacologiche e metodo per la sua fabbricazione |
DE19936395C2 (de) | 1999-08-03 | 2002-07-18 | Antonia Buntz | Kosmetikpflaster und Verfahren zum Anheben der weiblichen Brust mittels eines solchen Kosmetikpflasters und seine Verwendung |
US6682757B1 (en) | 2000-11-16 | 2004-01-27 | Euro-Celtique, S.A. | Titratable dosage transdermal delivery system |
US7795263B2 (en) * | 2008-07-08 | 2010-09-14 | Wildlife Laboratories, Inc. | Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals |
KR101859486B1 (ko) * | 2009-05-15 | 2018-06-28 | 레크로파마, 인코포레이티드 | 설하용 덱스메데토미딘 조성물과 그의 사용 방법 |
JP2013516482A (ja) * | 2010-01-08 | 2013-05-13 | レクロ・ファーマ,インコーポレーテッド | 局所経皮用デクスメデトミジン組成物およびそれらの使用方法 |
US20120202863A1 (en) * | 2011-02-03 | 2012-08-09 | Gerald Horn | Compositions and methods for treatment of glaucoma |
AU2012352528B9 (en) | 2011-12-11 | 2017-11-02 | Baudax Bio, Inc. | Intranasal dexmedetomidine compositions and methods of use thereof |
US10772871B2 (en) | 2013-10-07 | 2020-09-15 | Teikoku Pharma Usa, Inc. | Dexmedetomidine transdermal delivery devices and methods for using the same |
TWI709417B (zh) * | 2013-10-07 | 2020-11-11 | 美商帝國製藥美國股份有限公司 | 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物 |
EP3054930B1 (en) | 2013-10-07 | 2020-12-02 | Teikoku Pharma USA, Inc. | Methods and compositions for transdermal delivery of a non-sedative amount of dexmedetomidine |
CA2924188C (en) * | 2013-10-07 | 2018-12-18 | Teikoku Pharma Usa, Inc. | Methods and compositions for managing pain comprising dexmedetomidine transdermal compositions |
RU2648817C2 (ru) * | 2013-10-07 | 2018-03-28 | ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. | Способы и композиции для лечения абстинентных синдромов с использованием неседативных трансдермальных композиций на основе дексмедетомидина |
US9974754B2 (en) | 2013-12-18 | 2018-05-22 | Maruishi Pharmaceutical Co., Ltd. | Hydrous adhesive patch |
CN111346072B (zh) * | 2018-12-21 | 2022-05-27 | 宜昌人福药业有限责任公司 | 一种透皮给药的药物组合物及其制备方法 |
US20220211672A1 (en) | 2019-05-01 | 2022-07-07 | Clexio Biosciences Ltd. | Methods of treating pruritus |
US11185532B2 (en) | 2019-05-01 | 2021-11-30 | Clexio Biosciences Ltd. | Methods of treating pruritus |
TWI772807B (zh) | 2019-05-27 | 2022-08-01 | 日商救急藥品工業股份有限公司 | 外用製劑 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2101114B (en) * | 1981-07-10 | 1985-05-22 | Farmos Group Ltd | Substituted imidazole derivatives and their preparation and use |
FI864570A0 (fi) | 1986-11-11 | 1986-11-11 | Farmos Oy | Terapeutiskt anvaendbar foerening. |
GB2206880B (en) * | 1987-07-16 | 1991-04-24 | Farmos Oy | Optical isomers of an imidazole derivative |
GB2215206B (en) * | 1988-02-29 | 1991-07-03 | Farmos Oy | 4-substituted imidazole derivatives useful in perioperative care |
US5217718A (en) * | 1989-08-18 | 1993-06-08 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
US5124157A (en) * | 1989-08-18 | 1992-06-23 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
US5304569A (en) * | 1989-11-13 | 1994-04-19 | Orion-Yhtyma Oy | Compositions and their use in lowering intraocular pressure |
-
1991
- 1991-05-31 GB GB919111732A patent/GB9111732D0/en active Pending
-
1992
- 1992-05-11 ZA ZA923395A patent/ZA923395B/xx unknown
- 1992-05-13 NZ NZ242717A patent/NZ242717A/en not_active IP Right Cessation
- 1992-05-22 GB GB9211033A patent/GB2256367B/en not_active Expired - Fee Related
- 1992-05-27 EP EP92917469A patent/EP0587819B1/en not_active Expired - Lifetime
- 1992-05-27 AU AU17981/92A patent/AU1798192A/en not_active Abandoned
- 1992-05-27 CA CA002110161A patent/CA2110161C/en not_active Expired - Lifetime
- 1992-05-27 DE DE69217658T patent/DE69217658T2/de not_active Expired - Fee Related
- 1992-05-27 WO PCT/FI1992/000167 patent/WO1992021338A1/en active IP Right Grant
- 1992-05-27 JP JP51014392A patent/JP3483881B2/ja not_active Expired - Fee Related
- 1992-05-27 AT AT92917469T patent/ATE149090T1/de not_active IP Right Cessation
- 1992-05-28 LV LVP-92-18A patent/LV10047B/en unknown
- 1992-05-29 LT LTIP112A patent/LT3130B/lt not_active IP Right Cessation
- 1992-07-01 IE IE921937A patent/IE67168B1/en not_active IP Right Cessation
-
1993
- 1993-11-12 US US08/146,201 patent/US5438067A/en not_active Expired - Fee Related
- 1993-11-29 NO NO934323A patent/NO303818B1/no unknown
- 1993-11-30 FI FI935351A patent/FI104948B/fi not_active IP Right Cessation
-
1994
- 1994-10-18 EE EE9400270A patent/EE03053B1/et not_active IP Right Cessation
-
2003
- 2003-06-20 JP JP2003175781A patent/JP2003327531A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP3483881B2 (ja) | 2004-01-06 |
ATE149090T1 (de) | 1997-03-15 |
GB2256367B (en) | 1995-03-15 |
JP2003327531A (ja) | 2003-11-19 |
GB9211033D0 (en) | 1992-07-08 |
JPH06507888A (ja) | 1994-09-08 |
LT3130B (en) | 1994-12-25 |
LV10047A (lv) | 1994-05-10 |
LTIP112A (en) | 1994-07-15 |
NZ242717A (en) | 1994-03-25 |
WO1992021338A1 (en) | 1992-12-10 |
FI935351A0 (fi) | 1993-11-30 |
DE69217658T2 (de) | 1997-07-03 |
NO303818B1 (no) | 1998-09-07 |
GB9111732D0 (en) | 1991-07-24 |
IE921937A1 (en) | 1992-12-02 |
IE67168B1 (en) | 1996-03-06 |
DE69217658D1 (de) | 1997-04-03 |
NO934323L (no) | 1993-11-29 |
CA2110161C (en) | 2004-08-03 |
CA2110161A1 (en) | 1992-12-10 |
EP0587819A1 (en) | 1994-03-23 |
LV10047B (en) | 1995-02-20 |
NO934323D0 (no) | 1993-11-29 |
FI935351A (fi) | 1993-11-30 |
FI104948B (fi) | 2000-05-15 |
EE03053B1 (et) | 1997-12-15 |
GB2256367A (en) | 1992-12-09 |
US5438067A (en) | 1995-08-01 |
EP0587819B1 (en) | 1997-02-26 |
AU1798192A (en) | 1993-01-08 |
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