LV10047B - The use of certain salts of medetomidine and their optically active enantiomers to regulate the rate of transdermal administration of the drugs - Google Patents

The use of certain salts of medetomidine and their optically active enantiomers to regulate the rate of transdermal administration of the drugs Download PDF

Info

Publication number
LV10047B
LV10047B LVP-92-18A LV920018A LV10047B LV 10047 B LV10047 B LV 10047B LV 920018 A LV920018 A LV 920018A LV 10047 B LV10047 B LV 10047B
Authority
LV
Latvia
Prior art keywords
drug
preparation
preparation according
medetomidine
adhesive layer
Prior art date
Application number
LVP-92-18A
Other languages
English (en)
Latvian (lv)
Other versions
LV10047A (lv
Inventor
Harry Jalonen
Arto Johannes Karjalainen
Original Assignee
Orion Yhtym Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtym Oy filed Critical Orion Yhtym Oy
Publication of LV10047A publication Critical patent/LV10047A/xx
Publication of LV10047B publication Critical patent/LV10047B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
LVP-92-18A 1991-05-31 1992-05-28 The use of certain salts of medetomidine and their optically active enantiomers to regulate the rate of transdermal administration of the drugs LV10047B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919111732A GB9111732D0 (en) 1991-05-31 1991-05-31 The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs

Publications (2)

Publication Number Publication Date
LV10047A LV10047A (lv) 1994-05-10
LV10047B true LV10047B (en) 1995-02-20

Family

ID=10695876

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-92-18A LV10047B (en) 1991-05-31 1992-05-28 The use of certain salts of medetomidine and their optically active enantiomers to regulate the rate of transdermal administration of the drugs

Country Status (17)

Country Link
US (1) US5438067A (et)
EP (1) EP0587819B1 (et)
JP (2) JP3483881B2 (et)
AT (1) ATE149090T1 (et)
AU (1) AU1798192A (et)
CA (1) CA2110161C (et)
DE (1) DE69217658T2 (et)
EE (1) EE03053B1 (et)
FI (1) FI104948B (et)
GB (2) GB9111732D0 (et)
IE (1) IE67168B1 (et)
LT (1) LT3130B (et)
LV (1) LV10047B (et)
NO (1) NO303818B1 (et)
NZ (1) NZ242717A (et)
WO (1) WO1992021338A1 (et)
ZA (1) ZA923395B (et)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883115A (en) * 1992-11-09 1999-03-16 Pharmetrix Division Technical Chemicals & Products, Inc. Transdermal delivery of the eutomer of a chiral drug
GB2290964A (en) * 1994-07-08 1996-01-17 Arto Olavi Urtti Transdermal drug delivery system
GB9521680D0 (en) * 1995-10-23 1996-01-03 Orion Yhtymo Oy New use of imidazole derivatives
US5730721A (en) 1996-01-25 1998-03-24 Vesture Corporation Medical applicator and method
GB9614098D0 (en) 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
IT1290255B1 (it) * 1997-02-05 1998-10-22 Wallcovering Pubblicita S R L Supporto sagomato aderente all'epidermide per la cessione di sostanze cosmetiche o farmacologiche e metodo per la sua fabbricazione
DE19936395C2 (de) 1999-08-03 2002-07-18 Antonia Buntz Kosmetikpflaster und Verfahren zum Anheben der weiblichen Brust mittels eines solchen Kosmetikpflasters und seine Verwendung
US6682757B1 (en) 2000-11-16 2004-01-27 Euro-Celtique, S.A. Titratable dosage transdermal delivery system
US7795263B2 (en) * 2008-07-08 2010-09-14 Wildlife Laboratories, Inc. Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals
AU2010248776B2 (en) * 2009-05-15 2013-06-06 Baudax Bio, Inc. Sublingual dexmedetomidine compositions and methods of use thereof
NZ703808A (en) * 2010-01-08 2016-01-29 Recro Pharma Inc Topical transdermal dexmedetomidine compositions and methods of use thereof
US20120202863A1 (en) * 2011-02-03 2012-08-09 Gerald Horn Compositions and methods for treatment of glaucoma
SG11201403094TA (en) 2011-12-11 2014-10-30 Recro Pharma Inc Intranasal dexmedetomidine compositions and methods of use thereof
KR101891186B1 (ko) * 2013-10-07 2018-08-24 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 조성물을 포함하는 통증을 관리하기 위한 방법 및 조성물
KR101831290B1 (ko) 2013-10-07 2018-02-22 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 조성물을 사용하여 주의력 결핍 과잉행동 장애, 불안 및 불면증을 치료하기 위한 방법 및 조성물
TWI704933B (zh) * 2013-10-07 2020-09-21 美商帝國製藥美國股份有限公司 右美托咪啶經皮輸送裝置及使用其之方法
FI3054934T3 (fi) * 2013-10-07 2024-07-19 Teikoku Pharma Usa Inc Menetelmät ja koostumukset vieroitusoireyhtymien hoitoon käyttäen ei-sedatiivisia transdermaalisia deksmedetomidiinikoostumuksia
CN105764496B (zh) * 2013-10-07 2020-09-25 帝国制药美国公司 用于经皮递送非镇静量的右旋美托咪啶的方法和组合物
US9974754B2 (en) 2013-12-18 2018-05-22 Maruishi Pharmaceutical Co., Ltd. Hydrous adhesive patch
CN111346072B (zh) * 2018-12-21 2022-05-27 宜昌人福药业有限责任公司 一种透皮给药的药物组合物及其制备方法
US20220211672A1 (en) 2019-05-01 2022-07-07 Clexio Biosciences Ltd. Methods of treating pruritus
US11185532B2 (en) 2019-05-01 2021-11-30 Clexio Biosciences Ltd. Methods of treating pruritus
TWI772807B (zh) 2019-05-27 2022-08-01 日商救急藥品工業股份有限公司 外用製劑

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
FI864570A0 (fi) * 1986-11-11 1986-11-11 Farmos Oy Terapeutiskt anvaendbar foerening.
GB2206880B (en) * 1987-07-16 1991-04-24 Farmos Oy Optical isomers of an imidazole derivative
GB2215206B (en) * 1988-02-29 1991-07-03 Farmos Oy 4-substituted imidazole derivatives useful in perioperative care
US5217718A (en) * 1989-08-18 1993-06-08 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5124157A (en) * 1989-08-18 1992-06-23 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5304569A (en) * 1989-11-13 1994-04-19 Orion-Yhtyma Oy Compositions and their use in lowering intraocular pressure

Also Published As

Publication number Publication date
JP2003327531A (ja) 2003-11-19
FI104948B (fi) 2000-05-15
DE69217658T2 (de) 1997-07-03
ZA923395B (en) 1993-03-31
FI935351A0 (fi) 1993-11-30
EP0587819A1 (en) 1994-03-23
AU1798192A (en) 1993-01-08
CA2110161A1 (en) 1992-12-10
NO303818B1 (no) 1998-09-07
NO934323L (no) 1993-11-29
GB9211033D0 (en) 1992-07-08
IE67168B1 (en) 1996-03-06
JP3483881B2 (ja) 2004-01-06
EP0587819B1 (en) 1997-02-26
LT3130B (en) 1994-12-25
CA2110161C (en) 2004-08-03
US5438067A (en) 1995-08-01
GB9111732D0 (en) 1991-07-24
FI935351A (fi) 1993-11-30
ATE149090T1 (de) 1997-03-15
LTIP112A (en) 1994-07-15
NZ242717A (en) 1994-03-25
EE03053B1 (et) 1997-12-15
DE69217658D1 (de) 1997-04-03
GB2256367A (en) 1992-12-09
IE921937A1 (en) 1992-12-02
JPH06507888A (ja) 1994-09-08
GB2256367B (en) 1995-03-15
WO1992021338A1 (en) 1992-12-10
NO934323D0 (no) 1993-11-29
LV10047A (lv) 1994-05-10

Similar Documents

Publication Publication Date Title
CA2110161C (en) Medetomidine preparations for transdermal administration
US5308625A (en) Enhancement of transdermal drug delivery using monoalkyl phosphates and other absorption promoters
CA2153166A1 (en) Enhanced pharmaceutical compositions for skin penetration
US5358715A (en) Enhancement of transdermal drug delivery using monoalkyl phosphates and other absorption promoters
US5464628A (en) Pharmaceutical compositions containing 4-substituted imidazoles to be administered transdermally
ZA200506056B (en) Formulation and methods for the treatment of thrombocythemia
US20210236417A1 (en) Transdermal delivery of dronabinol
JP2838297B2 (ja) コルヒチン含有外用剤
KR101680801B1 (ko) 피부자극이 완화된 경피흡수제제
WO1991009634A1 (de) Mittel zur transdermalen applikation enthaltend rolipram
JP2717859B2 (ja) 経皮吸収製剤
JP2010229088A (ja) 経皮吸収製剤
CA2184198A1 (en) Enhancement of transdermal drug delivery using monoalkyl phosphates and other absorption promoters