ZA921985B - Anti-cancer compounds. - Google Patents

Anti-cancer compounds.

Info

Publication number
ZA921985B
ZA921985B ZA921985A ZA921985A ZA921985B ZA 921985 B ZA921985 B ZA 921985B ZA 921985 A ZA921985 A ZA 921985A ZA 921985 A ZA921985 A ZA 921985A ZA 921985 B ZA921985 B ZA 921985B
Authority
ZA
South Africa
Prior art keywords
cancer compounds
cancer
compounds
Prior art date
Application number
ZA921985A
Other languages
English (en)
Inventor
Graham Michael Fraser Bisset
Ann Lesley Jackmann
Duncan Ian Jodrell
Original Assignee
British Tech Group
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Tech Group, Ici Plc filed Critical British Tech Group
Publication of ZA921985B publication Critical patent/ZA921985B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA921985A 1991-03-19 1992-03-18 Anti-cancer compounds. ZA921985B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919105771A GB9105771D0 (en) 1991-03-19 1991-03-19 Anti-cancer compounds

Publications (1)

Publication Number Publication Date
ZA921985B true ZA921985B (en) 1993-09-20

Family

ID=10691801

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA921985A ZA921985B (en) 1991-03-19 1992-03-18 Anti-cancer compounds.

Country Status (18)

Country Link
US (1) US5444061A (ko)
EP (1) EP0509643A1 (ko)
JP (1) JPH06505974A (ko)
AU (1) AU655970B2 (ko)
CA (1) CA2106583A1 (ko)
CZ (1) CZ195393A3 (ko)
FI (1) FI934106A (ko)
GB (2) GB9105771D0 (ko)
HU (1) HUT67177A (ko)
IE (1) IE920853A1 (ko)
IL (1) IL101281A0 (ko)
MX (1) MX9201183A (ko)
NO (1) NO933341L (ko)
NZ (1) NZ242023A (ko)
SK (1) SK100993A3 (ko)
TW (1) TW203608B (ko)
WO (1) WO1992016512A1 (ko)
ZA (1) ZA921985B (ko)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9205907D0 (en) * 1992-03-18 1992-04-29 Cancer Res Inst Royal Anti-cancer compounds
GB9223352D0 (en) * 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds
GB9408936D0 (en) * 1994-05-05 1994-06-22 Cancer Res Inst Anti-cancer compounds
MX9801716A (es) * 1995-08-30 1998-05-31 Searle & Co Derivados de meta-guanidina, urea, tiourea o acido aminobenzoico azaciclico, como antagonistas de integrina.
GB9904275D0 (en) 1999-02-24 1999-04-21 Cancer Res Campaign Tech Anti-cancer compounds
US7671200B2 (en) 1999-10-27 2010-03-02 Cytokinetics, Inc. Quinazolinone KSP inhibitors
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
US7009049B2 (en) * 2002-02-15 2006-03-07 Cytokinetics, Inc. Syntheses of quinazolinones
WO2003097053A1 (en) 2002-05-09 2003-11-27 Cytokinetics, Inc. Compounds, compositions, and methods
JP2006508030A (ja) * 2002-05-09 2006-03-09 サイトキネティクス・インコーポレーテッド ピリミジノン化合物、組成物および方法
WO2003103575A2 (en) * 2002-05-23 2003-12-18 Cytokinetics, Inc. Compounds, compositions, and methods
US7041676B2 (en) * 2002-06-14 2006-05-09 Cytokinetics, Inc. Compounds, compositions, and methods
US20030236430A1 (en) * 2002-06-21 2003-12-25 Allen David Robert Preparation of protected amino acids
EP1537089A4 (en) * 2002-07-23 2008-04-16 Cytokinetics Inc CONNECTIONS, COMPOSITIONS AND PROCEDURES
JP2005536553A (ja) * 2002-08-21 2005-12-02 サイトキネティクス・インコーポレーテッド 化合物、組成物および方法
US7557115B2 (en) * 2002-09-30 2009-07-07 Cytokinetics, Inc. Compounds, compositions, and methods
EP1682534A2 (en) * 2003-11-03 2006-07-26 Cytokinetics, Inc. Pyrimidin-4-one compounds, compositions, and methods
US20050148593A1 (en) * 2003-11-07 2005-07-07 Gustave Bergnes Compounds, compositions, and methods
EP1692112A4 (en) * 2003-12-08 2008-09-24 Cytokinetics Inc COMPOUNDS, COMPOSITIONS, AND METHODS
CA2670379C (en) 2007-04-11 2015-06-23 Merck Eprova Ag 18f-labelled folates
CA2959208C (en) 2014-08-29 2023-09-19 Tes Pharma S.R.L. Pyrimidine derivatives and their use as inhibitors of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase
JP2022500499A (ja) 2018-09-07 2022-01-04 ピク セラピューティクス， インコーポレイテッド Ｅｉｆ４ｅ阻害剤およびその使用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3069468D1 (en) * 1979-12-19 1984-11-22 Nat Res Dev Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents
GB8513754D0 (en) * 1985-05-31 1985-07-03 Jones T R Anti-cancer quinazoline derivatives
US4746659A (en) * 1985-12-30 1988-05-24 Sri International Diastereomers of 10-alkyl-10-deazaminopterins and process for preparing the same
GB8607683D0 (en) * 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents
US5187167A (en) * 1986-03-27 1993-02-16 Imperial Chemical Industries Plc Pharmaceutical compositions comprising quinazolin-4-one derivatives
GB8625019D0 (en) * 1986-10-18 1986-11-19 Wellcome Found Compounds
GB8707053D0 (en) * 1987-03-25 1987-04-29 Ici Plc Anti-tumour agents
US4767761A (en) * 1987-11-04 1988-08-30 Dana-Farber Cancer Institute, Inc. Ornithine derivatives and their use as methotrexate-resistant cell inhibitors
GB8727737D0 (en) * 1987-11-26 1987-12-31 Ici Plc Antitumour agents
GB8809978D0 (en) * 1988-04-27 1988-06-02 Ici Plc Anti-tumour agents
GB8829296D0 (en) * 1988-12-15 1989-01-25 Ici Plc Anti-tumour compounds
US5252573A (en) * 1988-12-15 1993-10-12 Imperial Chemical Industries Plc Anti-tumor agents
US4996207A (en) * 1990-01-18 1991-02-26 Nair Madhavan G Three new non-polyglutamatable deazaaminopterins
EP0457529B1 (en) * 1990-05-17 1995-08-09 SMITH & NEPHEW UNITED, INC. An electroconductive and astringent film and film-forming composition for application to skin
ZA913730B (en) * 1990-05-30 1992-02-26 Ici Plc Anti-tumor compounds

Also Published As

Publication number Publication date
IE920853A1 (en) 1992-09-23
AU1371692A (en) 1992-10-21
FI934106A0 (fi) 1993-09-20
WO1992016512A1 (en) 1992-10-01
HUT67177A (en) 1995-02-28
US5444061A (en) 1995-08-22
GB2253849A (en) 1992-09-23
AU655970B2 (en) 1995-01-19
CA2106583A1 (en) 1992-09-20
NO933341D0 (no) 1993-09-20
EP0509643A1 (en) 1992-10-21
IL101281A0 (en) 1992-11-15
SK100993A3 (en) 1994-08-10
GB9105771D0 (en) 1991-05-01
GB2253849B (en) 1995-01-18
CZ195393A3 (en) 1994-07-13
NO933341L (no) 1993-11-18
GB9205906D0 (en) 1992-04-29
NZ242023A (en) 1993-12-23
JPH06505974A (ja) 1994-07-07
HU9302636D0 (en) 1993-12-28
FI934106A (fi) 1993-11-18
MX9201183A (es) 1994-06-30
TW203608B (ko) 1993-04-11

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