IL101281A0 - Anti-cancer compounds and compositions - Google Patents

Anti-cancer compounds and compositions

Info

Publication number
IL101281A0
IL101281A0 IL101281A IL10128192A IL101281A0 IL 101281 A0 IL101281 A0 IL 101281A0 IL 101281 A IL101281 A IL 101281A IL 10128192 A IL10128192 A IL 10128192A IL 101281 A0 IL101281 A0 IL 101281A0
Authority
IL
Israel
Prior art keywords
compositions
cancer compounds
cancer
compounds
Prior art date
Application number
IL101281A
Other languages
English (en)
Original Assignee
British Tech Group
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Tech Group, Ici Plc filed Critical British Tech Group
Publication of IL101281A0 publication Critical patent/IL101281A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • C07D239/90Oxygen atoms with acyclic radicals attached in position 2 or 3

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL101281A 1991-03-19 1992-03-18 Anti-cancer compounds and compositions IL101281A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919105771A GB9105771D0 (en) 1991-03-19 1991-03-19 Anti-cancer compounds

Publications (1)

Publication Number Publication Date
IL101281A0 true IL101281A0 (en) 1992-11-15

Family

ID=10691801

Family Applications (1)

Application Number Title Priority Date Filing Date
IL101281A IL101281A0 (en) 1991-03-19 1992-03-18 Anti-cancer compounds and compositions

Country Status (18)

Country Link
US (1) US5444061A (ko)
EP (1) EP0509643A1 (ko)
JP (1) JPH06505974A (ko)
AU (1) AU655970B2 (ko)
CA (1) CA2106583A1 (ko)
CZ (1) CZ195393A3 (ko)
FI (1) FI934106A (ko)
GB (2) GB9105771D0 (ko)
HU (1) HUT67177A (ko)
IE (1) IE920853A1 (ko)
IL (1) IL101281A0 (ko)
MX (1) MX9201183A (ko)
NO (1) NO933341L (ko)
NZ (1) NZ242023A (ko)
SK (1) SK100993A3 (ko)
TW (1) TW203608B (ko)
WO (1) WO1992016512A1 (ko)
ZA (1) ZA921985B (ko)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9205907D0 (en) * 1992-03-18 1992-04-29 Cancer Res Inst Royal Anti-cancer compounds
GB9223352D0 (en) * 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds
GB9408936D0 (en) * 1994-05-05 1994-06-22 Cancer Res Inst Anti-cancer compounds
DE69613985T2 (de) * 1995-08-30 2002-06-13 G.D. Searle & Co., Chicago Meta-guanidine, harnstoff, thioharnstoff oder azacyklische aminobenzoesäure-derivate als integrin antagonisten
GB9904275D0 (en) 1999-02-24 1999-04-21 Cancer Res Campaign Tech Anti-cancer compounds
US7230000B1 (en) 1999-10-27 2007-06-12 Cytokinetics, Incorporated Methods and compositions utilizing quinazolinones
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
US7671200B2 (en) * 1999-10-27 2010-03-02 Cytokinetics, Inc. Quinazolinone KSP inhibitors
AU2003213092A1 (en) * 2002-02-15 2003-09-09 Smithkline Beecham Corporation Syntheses of quinazolinones
JP2005530785A (ja) * 2002-05-09 2005-10-13 サイトキネティクス・インコーポレーテッド 化合物、組成物、及び方法
BR0309892A2 (pt) * 2002-05-09 2011-04-05 Cytokinetics Inc composto, composição, métodos para modular a atividade da cinesina de ksp, para inibir a ksp, e para o tratamento de uma doença proliferativa celular, e, uso de um composto
US7038048B2 (en) * 2002-05-23 2006-05-02 Cytokinetics, Inc. 3H-pyridopyrimidin-4-one compounds, compositions, and methods of their use
EP1556357A4 (en) * 2002-06-14 2006-09-13 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
US20030236430A1 (en) * 2002-06-21 2003-12-25 Allen David Robert Preparation of protected amino acids
AU2003256805A1 (en) * 2002-07-23 2004-02-09 Cytokinetics, Inc. Compounds compositions and methods
US20040048853A1 (en) * 2002-08-21 2004-03-11 Gustave Bergnes Compounds, compositions, and methods
EP1558083A4 (en) * 2002-09-30 2008-04-16 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
JP2007510652A (ja) * 2003-11-03 2007-04-26 サイトキネティクス・インコーポレーテッド ピリミジン−4−オン化合物、組成物、および方法
EP1680420A4 (en) * 2003-11-07 2008-09-24 Cytokinetics Inc COMPOUNDS, COMPOSITIONS AND METHODS
JP2007513154A (ja) * 2003-12-08 2007-05-24 サイトキネティクス・インコーポレーテッド 化合物、組成物及び方法
JP5693950B2 (ja) 2007-04-11 2015-04-01 メルク エ カンパニー 18f標識葉酸
CA2959208C (en) 2014-08-29 2023-09-19 Tes Pharma S.R.L. Pyrimidine derivatives and their use as inhibitors of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase
EP3846793B1 (en) 2018-09-07 2024-01-24 PIC Therapeutics, Inc. Eif4e inhibitors and uses thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2065653B (en) * 1979-12-19 1983-03-09 Nat Res Dev Anti-cancer quinazoline derivatives
GB8513754D0 (en) * 1985-05-31 1985-07-03 Jones T R Anti-cancer quinazoline derivatives
US4746659A (en) * 1985-12-30 1988-05-24 Sri International Diastereomers of 10-alkyl-10-deazaminopterins and process for preparing the same
US5187167A (en) * 1986-03-27 1993-02-16 Imperial Chemical Industries Plc Pharmaceutical compositions comprising quinazolin-4-one derivatives
GB8607683D0 (en) * 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents
GB8625019D0 (en) * 1986-10-18 1986-11-19 Wellcome Found Compounds
GB8707053D0 (en) * 1987-03-25 1987-04-29 Ici Plc Anti-tumour agents
US4767761A (en) * 1987-11-04 1988-08-30 Dana-Farber Cancer Institute, Inc. Ornithine derivatives and their use as methotrexate-resistant cell inhibitors
GB8727737D0 (en) * 1987-11-26 1987-12-31 Ici Plc Antitumour agents
GB8809978D0 (en) * 1988-04-27 1988-06-02 Ici Plc Anti-tumour agents
US5252573A (en) * 1988-12-15 1993-10-12 Imperial Chemical Industries Plc Anti-tumor agents
GB8829296D0 (en) * 1988-12-15 1989-01-25 Ici Plc Anti-tumour compounds
US4996207A (en) * 1990-01-18 1991-02-26 Nair Madhavan G Three new non-polyglutamatable deazaaminopterins
DE69111891T2 (de) * 1990-05-17 1996-04-04 Smith & Nephew United Inc Elektrisch leitender und adstringierender Film sowie filmbildende Zusammensetzung zur Verwendung auf der Haut.
AU640016B2 (en) * 1990-05-30 1993-08-12 Imperial Chemical Industries Plc Hydroquinazoline derivatives

Also Published As

Publication number Publication date
TW203608B (ko) 1993-04-11
WO1992016512A1 (en) 1992-10-01
NO933341L (no) 1993-11-18
ZA921985B (en) 1993-09-20
GB2253849B (en) 1995-01-18
GB9105771D0 (en) 1991-05-01
HUT67177A (en) 1995-02-28
JPH06505974A (ja) 1994-07-07
CA2106583A1 (en) 1992-09-20
MX9201183A (es) 1994-06-30
NZ242023A (en) 1993-12-23
FI934106A (fi) 1993-11-18
CZ195393A3 (en) 1994-07-13
GB2253849A (en) 1992-09-23
FI934106A0 (fi) 1993-09-20
IE920853A1 (en) 1992-09-23
HU9302636D0 (en) 1993-12-28
US5444061A (en) 1995-08-22
GB9205906D0 (en) 1992-04-29
EP0509643A1 (en) 1992-10-21
AU655970B2 (en) 1995-01-19
AU1371692A (en) 1992-10-21
NO933341D0 (no) 1993-09-20
SK100993A3 (en) 1994-08-10

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