ZA921268B - 2-substituted quinolines,processes for their preparation and their use in medicaments - Google Patents

2-substituted quinolines,processes for their preparation and their use in medicaments

Info

Publication number
ZA921268B
ZA921268B ZA921268A ZA921268A ZA921268B ZA 921268 B ZA921268 B ZA 921268B ZA 921268 A ZA921268 A ZA 921268A ZA 921268 A ZA921268 A ZA 921268A ZA 921268 B ZA921268 B ZA 921268B
Authority
ZA
South Africa
Prior art keywords
substituted
medicaments
substituted quinolines
processes
preparation
Prior art date
Application number
ZA921268A
Other languages
English (en)
Inventor
Siegfried Raddatz
Raddatz Siegfried
Klaus-Helmut Mohrs
Mohrs Klaus-Helmut
Michael Matzke
Matzke Michael
Romanis Fruchtmann
Fruchtmann Romanis
Armin Hatzelmann
Hatzelmann Armin
Christian Kohlsdorfer
Kohlsdorfer Christian
Reiner Mueller-Peddinghaus
Mueller-Peddinghaus Reiner
Pia Theisen-Popp
Theisen-Popp Pia
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA921268B publication Critical patent/ZA921268B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Electrically Operated Instructional Devices (AREA)
  • Earth Drilling (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA921268A 1991-02-22 1992-02-21 2-substituted quinolines,processes for their preparation and their use in medicaments ZA921268B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4105551A DE4105551A1 (de) 1991-02-22 1991-02-22 2-substituierte chinoline, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln

Publications (1)

Publication Number Publication Date
ZA921268B true ZA921268B (en) 1992-11-25

Family

ID=6425643

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA921268A ZA921268B (en) 1991-02-22 1992-02-21 2-substituted quinolines,processes for their preparation and their use in medicaments

Country Status (20)

Country Link
EP (1) EP0499926B1 (ja)
JP (1) JPH0592957A (ja)
KR (1) KR920016424A (ja)
AT (1) ATE142623T1 (ja)
AU (1) AU641585B2 (ja)
CZ (1) CZ282723B6 (ja)
DE (2) DE4105551A1 (ja)
DK (1) DK0499926T3 (ja)
ES (1) ES2091958T3 (ja)
FI (1) FI920732A (ja)
GR (1) GR3021014T3 (ja)
HU (1) HUT67037A (ja)
IE (1) IE75728B1 (ja)
IL (1) IL101009A (ja)
MY (1) MY108459A (ja)
NZ (1) NZ241654A (ja)
PL (2) PL171026B1 (ja)
RU (1) RU2077532C1 (ja)
TW (1) TW200463B (ja)
ZA (1) ZA921268B (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304563A (en) * 1991-02-22 1994-04-19 Bayer Aktiengesellschaft 2-substituted quinolines, and their use in medicaments
DE4226649A1 (de) * 1992-08-12 1994-02-17 Bayer Ag Neue isobutylsubstituierte Methansulfonyl-chinolylmethoxyphenyl-cycloalkylessigsäureaminole
DE4112533A1 (de) * 1991-04-17 1992-10-22 Bayer Ag Verfahren zur herstellung von enantiomerenreinen substituierten (chinolin-2-yl-methoxy)phenyl-essigsaeuren
US5391555A (en) * 1991-11-12 1995-02-21 Miles Inc. Methods for treating inflammatory bowel disease with leukotriene synthesis inhibitors
TW232013B (ja) * 1992-04-24 1994-10-11 Takeda Pharm Industry Co Ltd
DE4219765A1 (de) * 1992-06-17 1993-12-23 Bayer Ag Substituierte (Benzothiazolyl- und Chinoxalyl-methoxy)phenylessigsäurederivate
DE4301900A1 (de) * 1993-01-25 1994-07-28 Bayer Ag 2-Oxochinolin-1-yl-methylphenylessigsäurederivate
ES2061406B1 (es) * 1993-05-07 1995-06-01 Uriach & Cia Sa J Nuevos derivados de la 2-(quinolina) con actividad farmacologica.
US5491172A (en) * 1993-05-14 1996-02-13 Warner-Lambert Company N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
IL109431A (en) * 1993-05-14 2001-01-11 Warner Lambert Co Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds
DE69422450T2 (de) * 1993-06-29 2000-06-08 Takeda Chemical Industries Ltd Chinoline oder Chinazolin-Derivate und deren Verwendung zur Herstellung eines Medikaments für die Behandlung von Osteoporose
DE4443891A1 (de) 1994-12-09 1996-06-13 Bayer Ag Heterocyclisch substituierte Oxy-phenyl-(phenyl)glycinolamide
DE4443892A1 (de) * 1994-12-09 1996-06-13 Bayer Ag 4-(Chinolin-2-yl-methoxy)-phenyl-essigsäurederivate
US6867320B2 (en) 2002-02-21 2005-03-15 Asahi Kasei Pharma Corporation Substituted phenylalkanoic acid derivatives and use thereof
CA2547518A1 (en) 2003-12-12 2005-06-30 Wyeth Quinolines useful in treating cardiovascular disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3814504A1 (de) * 1988-04-29 1989-11-09 Bayer Ag (alpha)-substituierte 4-(chinolin-2-yl-methoxy)phenylessigsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3900261A1 (de) * 1988-05-31 1989-12-07 Bayer Ag Substituierte 4-(chinolin-2-yl-methoxy) phenyl-essigsaeure-derivate
DE3908298A1 (de) * 1989-03-14 1990-09-20 Bayer Ag Substituierte (chinolin-2-yl-methoxy)phenyl-n,n'-sulfonylharnstoffe, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3916663A1 (de) * 1989-05-23 1990-11-29 Bayer Ag Substituierte (chinolin-2-yl-methoxy)phenyl-acyl-sulfonamide und -cyanamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3927930A1 (de) * 1989-08-24 1991-02-28 Bayer Ag Cyclisch substituierte (chinolin-2-yl-methoxy)phenyl-essig-saeure-derivate
DE3927931A1 (de) * 1989-08-24 1991-02-28 Bayer Ag Disubstituierte (chinolin-2-yl-methoxy)phenylessigsaeure-derivate

Also Published As

Publication number Publication date
GR3021014T3 (en) 1996-12-31
JPH0592957A (ja) 1993-04-16
KR920016424A (ko) 1992-09-24
RU2077532C1 (ru) 1997-04-20
PL293534A1 (en) 1992-10-05
ES2091958T3 (es) 1996-11-16
AU641585B2 (en) 1993-09-23
EP0499926B1 (de) 1996-09-11
HU9200582D0 (en) 1992-05-28
PL170726B1 (pl) 1997-01-31
EP0499926A1 (de) 1992-08-26
MY108459A (en) 1996-09-30
DK0499926T3 (ja) 1997-02-10
NZ241654A (en) 1994-11-25
CZ282723B6 (cs) 1997-09-17
AU1054292A (en) 1992-08-27
ATE142623T1 (de) 1996-09-15
IE75728B1 (en) 1997-09-24
FI920732A (fi) 1992-08-23
IL101009A (en) 1996-08-04
DE59207074D1 (de) 1996-10-17
DE4105551A1 (de) 1992-08-27
IL101009A0 (en) 1992-11-15
CS51492A3 (en) 1992-12-16
FI920732A0 (fi) 1992-02-20
HUT67037A (en) 1995-01-30
PL171026B1 (pl) 1997-02-28
IE920557A1 (en) 1992-08-26
TW200463B (ja) 1993-02-21

Similar Documents

Publication Publication Date Title
ZA921268B (en) 2-substituted quinolines,processes for their preparation and their use in medicaments
EP0302525A3 (en) Quinolones as antibacterial agents
DK543787A (da) Naphthyridin-, quinolin- og benzoxazincarboxylsyreforbindelser med antibakteriel aktivitet
JPS5547658A (en) Substituted quinolinecarboxylic acid derivative
KR950011747B1 (en) Quinoline carboxylic acid perivatives
DK0612731T3 (da) Nye quinolon- og naphthyridoncarboxylsyrederivater
JPS57145862A (en) Quinolinecarboxylic acid derivative
AU589415B2 (en) Improved process for quinoline-3-carboxylic acid antibacterial agents
EP0712844A4 (en) NOVEL CARBOXYLIC ACID COMPOUND WITH FUSED CORE OR SALT THEREOF, AND ITS USE IN MEDICINE
ES8802613A1 (es) Procedimiento para la obtencion del acido 1-ciclopropil-6-fluor-1,4-dihidro-7-(4-isopropil-1-piperazinil)-4-oxo-3-quinolincarboxilico
JPS57109754A (en) N-benzoyl-omega-anilinoalkane carboxylic acid compound
EP0207497A3 (en) Quinolonecarboxylic acid derivative and process for its preparation
NO177302C (no) Analogifremgangsmåte til fremstilling av terapeutisk aktive substituerte azetidinylkinolon(naftyridon)karboksylsyrederivater
GR3020230T3 (en) Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments
JPS5770889A (en) 1-ethyl-1,8-naphthyridine derivative and salt thereof
IE42992L (en) PYRIMIDO [1,2-a] QUINOLINE DERIVATIVES
ES2051225A1 (es) Procedimiento de preparacion del acido 1-etil-6-fluoro-7-(pirrol-1-il) -1,4-dihidro-4-oxo-3-quinoleincarboxilico.
JPS55100365A (en) Quinoline derivative and its preparation
FI922482A (fi) Foerfarande foer framstaellning av kinolinfoerening.
IE811069L (en) Esters of substituted benzoic acid
GB1453427A (en) 4-oxo-1,2,3,4-tetrahydropyrido-2,3-d-pyrimidines
ES2010462A6 (es) Procedimiento para obtener ciprofloxacina.