ZA918025B - Acetylenes disubstituted with a heteroaromatic group and a 2-substituted cromanyl,thiocromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity - Google Patents
Acetylenes disubstituted with a heteroaromatic group and a 2-substituted cromanyl,thiocromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activityInfo
- Publication number
- ZA918025B ZA918025B ZA918025A ZA918025A ZA918025B ZA 918025 B ZA918025 B ZA 918025B ZA 918025 A ZA918025 A ZA 918025A ZA 918025 A ZA918025 A ZA 918025A ZA 918025 B ZA918025 B ZA 918025B
- Authority
- ZA
- South Africa
- Prior art keywords
- group
- thiocromanyl
- cromanyl
- retinoid
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59512890A | 1990-10-09 | 1990-10-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA918025B true ZA918025B (en) | 1992-06-24 |
Family
ID=24381853
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA918025A ZA918025B (en) | 1990-10-09 | 1991-10-08 | Acetylenes disubstituted with a heteroaromatic group and a 2-substituted cromanyl,thiocromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0555235A4 (hu) |
JP (1) | JPH06501684A (hu) |
AU (1) | AU657100B2 (hu) |
CA (1) | CA2091763A1 (hu) |
FI (1) | FI931624A (hu) |
HU (1) | HUT63412A (hu) |
IE (1) | IE913568A1 (hu) |
IL (1) | IL99618A0 (hu) |
NZ (1) | NZ240059A (hu) |
PL (1) | PL168075B1 (hu) |
PT (1) | PT99189A (hu) |
WO (1) | WO1992006092A1 (hu) |
ZA (1) | ZA918025B (hu) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5602130A (en) * | 1987-03-20 | 1997-02-11 | Allergan | Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity |
US7452911B2 (en) | 2002-10-31 | 2008-11-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds |
CN107176945B (zh) | 2016-03-11 | 2021-06-08 | 中国科学院上海有机化学研究所 | 一种视黄酸类化合物、其制备方法、中间体及应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3816466A (en) * | 1971-12-22 | 1974-06-11 | Warner Lambert Co | Flavanoid ring systems |
US3868379A (en) * | 1972-04-28 | 1975-02-25 | Warner Lambert Co | Heterocyclic amides of 4-hydroxy-2H-1-benzothiopyran-3-carboxylic acid 1,1-dioxide |
CA1305480C (en) * | 1987-03-20 | 1992-07-21 | Roshantha A.S. Chandraratna | Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity |
US5023341A (en) * | 1989-09-19 | 1991-06-11 | Allergan, Inc. | Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity |
US5045551A (en) * | 1989-09-19 | 1991-09-03 | Allergan, Inc. | Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity |
-
1991
- 1991-09-24 WO PCT/US1991/006900 patent/WO1992006092A1/en not_active Application Discontinuation
- 1991-09-24 JP JP3515926A patent/JPH06501684A/ja active Pending
- 1991-09-24 CA CA002091763A patent/CA2091763A1/en not_active Abandoned
- 1991-09-24 EP EP19910917319 patent/EP0555235A4/en not_active Withdrawn
- 1991-09-24 HU HU931031A patent/HUT63412A/hu unknown
- 1991-09-24 AU AU86149/91A patent/AU657100B2/en not_active Ceased
- 1991-09-24 PL PL91299062A patent/PL168075B1/pl not_active IP Right Cessation
- 1991-10-01 NZ NZ240059A patent/NZ240059A/xx unknown
- 1991-10-01 IL IL99618A patent/IL99618A0/xx unknown
- 1991-10-08 ZA ZA918025A patent/ZA918025B/xx unknown
- 1991-10-09 PT PT99189A patent/PT99189A/pt not_active Application Discontinuation
- 1991-10-16 IE IE356891A patent/IE913568A1/en not_active Application Discontinuation
-
1993
- 1993-04-08 FI FI931624A patent/FI931624A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HUT63412A (en) | 1993-08-30 |
JPH06501684A (ja) | 1994-02-24 |
PL168075B1 (pl) | 1995-12-30 |
FI931624A0 (fi) | 1993-04-08 |
HU9301031D0 (en) | 1993-07-28 |
CA2091763A1 (en) | 1992-04-10 |
AU657100B2 (en) | 1995-03-02 |
WO1992006092A1 (en) | 1992-04-16 |
EP0555235A1 (en) | 1993-08-18 |
IL99618A0 (en) | 1992-08-18 |
FI931624A (fi) | 1993-04-08 |
IE913568A1 (en) | 1992-04-22 |
EP0555235A4 (en) | 1993-11-10 |
PT99189A (pt) | 1992-09-30 |
AU8614991A (en) | 1992-04-28 |
NZ240059A (en) | 1993-10-26 |
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