HUT63412A - Process for producing acethylene derivatives substituted with chromanyl, thiochromanyl or tetrahydroquinolinyl group and heteromatic group and having retinoid-like activity, as well as pharmaceutical compositions comprising sqme as active ingredient - Google Patents

Process for producing acethylene derivatives substituted with chromanyl, thiochromanyl or tetrahydroquinolinyl group and heteromatic group and having retinoid-like activity, as well as pharmaceutical compositions comprising sqme as active ingredient

Info

Publication number
HUT63412A
HUT63412A HU931031A HU103193A HUT63412A HU T63412 A HUT63412 A HU T63412A HU 931031 A HU931031 A HU 931031A HU 103193 A HU103193 A HU 103193A HU T63412 A HUT63412 A HU T63412A
Authority
HU
Hungary
Prior art keywords
group
heteromatic
sqme
acethylene
thiochromanyl
Prior art date
Application number
HU931031A
Other languages
English (en)
Other versions
HU9301031D0 (en
Inventor
Roshantha Chandraratna
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of HU9301031D0 publication Critical patent/HU9301031D0/hu
Publication of HUT63412A publication Critical patent/HUT63412A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
HU931031A 1990-10-09 1991-09-24 Process for producing acethylene derivatives substituted with chromanyl, thiochromanyl or tetrahydroquinolinyl group and heteromatic group and having retinoid-like activity, as well as pharmaceutical compositions comprising sqme as active ingredient HUT63412A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59512890A 1990-10-09 1990-10-09

Publications (2)

Publication Number Publication Date
HU9301031D0 HU9301031D0 (en) 1993-07-28
HUT63412A true HUT63412A (en) 1993-08-30

Family

ID=24381853

Family Applications (1)

Application Number Title Priority Date Filing Date
HU931031A HUT63412A (en) 1990-10-09 1991-09-24 Process for producing acethylene derivatives substituted with chromanyl, thiochromanyl or tetrahydroquinolinyl group and heteromatic group and having retinoid-like activity, as well as pharmaceutical compositions comprising sqme as active ingredient

Country Status (13)

Country Link
EP (1) EP0555235A4 (hu)
JP (1) JPH06501684A (hu)
AU (1) AU657100B2 (hu)
CA (1) CA2091763A1 (hu)
FI (1) FI931624A0 (hu)
HU (1) HUT63412A (hu)
IE (1) IE913568A1 (hu)
IL (1) IL99618A0 (hu)
NZ (1) NZ240059A (hu)
PL (1) PL168075B1 (hu)
PT (1) PT99189A (hu)
WO (1) WO1992006092A1 (hu)
ZA (1) ZA918025B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5602130A (en) * 1987-03-20 1997-02-11 Allergan Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
US7452911B2 (en) 2002-10-31 2008-11-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
CN107176945B (zh) 2016-03-11 2021-06-08 中国科学院上海有机化学研究所 一种视黄酸类化合物、其制备方法、中间体及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3816466A (en) * 1971-12-22 1974-06-11 Warner Lambert Co Flavanoid ring systems
US3868379A (en) * 1972-04-28 1975-02-25 Warner Lambert Co Heterocyclic amides of 4-hydroxy-2H-1-benzothiopyran-3-carboxylic acid 1,1-dioxide
CA1305480C (en) * 1987-03-20 1992-07-21 Roshantha A.S. Chandraratna Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
US5045551A (en) * 1989-09-19 1991-09-03 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5023341A (en) * 1989-09-19 1991-06-11 Allergan, Inc. Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity

Also Published As

Publication number Publication date
AU657100B2 (en) 1995-03-02
FI931624A (fi) 1993-04-08
PT99189A (pt) 1992-09-30
NZ240059A (en) 1993-10-26
IE913568A1 (en) 1992-04-22
EP0555235A1 (en) 1993-08-18
JPH06501684A (ja) 1994-02-24
IL99618A0 (en) 1992-08-18
CA2091763A1 (en) 1992-04-10
HU9301031D0 (en) 1993-07-28
FI931624A0 (fi) 1993-04-08
WO1992006092A1 (en) 1992-04-16
AU8614991A (en) 1992-04-28
EP0555235A4 (en) 1993-11-10
ZA918025B (en) 1992-06-24
PL168075B1 (pl) 1995-12-30

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Legal Events

Date Code Title Description
DFD9 Temporary protection cancelled due to non-payment of fee