HU9301031D0 - An acetylene derivative hqving retinoide-like effect being substituted with heter-aromatic group and chromanyl, thio-chromanyl or tetra-hydro-quinoline one - Google Patents

An acetylene derivative hqving retinoide-like effect being substituted with heter-aromatic group and chromanyl, thio-chromanyl or tetra-hydro-quinoline one

Info

Publication number
HU9301031D0
HU9301031D0 HU931031A HU103193A HU9301031D0 HU 9301031 D0 HU9301031 D0 HU 9301031D0 HU 931031 A HU931031 A HU 931031A HU 103193 A HU103193 A HU 103193A HU 9301031 D0 HU9301031 D0 HU 9301031D0
Authority
HU
Hungary
Prior art keywords
chromanyl
hqving
retinoide
heter
thio
Prior art date
Application number
HU931031A
Other languages
Hungarian (hu)
Other versions
HUT63412A (en
Inventor
Roshantha Chandraratna
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of HU9301031D0 publication Critical patent/HU9301031D0/en
Publication of HUT63412A publication Critical patent/HUT63412A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU931031A 1990-10-09 1991-09-24 Process for producing acethylene derivatives substituted with chromanyl, thiochromanyl or tetrahydroquinolinyl group and heteromatic group and having retinoid-like activity, as well as pharmaceutical compositions comprising sqme as active ingredient HUT63412A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59512890A 1990-10-09 1990-10-09

Publications (2)

Publication Number Publication Date
HU9301031D0 true HU9301031D0 (en) 1993-07-28
HUT63412A HUT63412A (en) 1993-08-30

Family

ID=24381853

Family Applications (1)

Application Number Title Priority Date Filing Date
HU931031A HUT63412A (en) 1990-10-09 1991-09-24 Process for producing acethylene derivatives substituted with chromanyl, thiochromanyl or tetrahydroquinolinyl group and heteromatic group and having retinoid-like activity, as well as pharmaceutical compositions comprising sqme as active ingredient

Country Status (13)

Country Link
EP (1) EP0555235A4 (en)
JP (1) JPH06501684A (en)
AU (1) AU657100B2 (en)
CA (1) CA2091763A1 (en)
FI (1) FI931624A (en)
HU (1) HUT63412A (en)
IE (1) IE913568A1 (en)
IL (1) IL99618A0 (en)
NZ (1) NZ240059A (en)
PL (1) PL168075B1 (en)
PT (1) PT99189A (en)
WO (1) WO1992006092A1 (en)
ZA (1) ZA918025B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5602130A (en) * 1987-03-20 1997-02-11 Allergan Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
US7452911B2 (en) 2002-10-31 2008-11-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
CN107176945B (en) 2016-03-11 2021-06-08 中国科学院上海有机化学研究所 Retinoid compound, preparation method, intermediate and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3816466A (en) * 1971-12-22 1974-06-11 Warner Lambert Co Flavanoid ring systems
US3868379A (en) * 1972-04-28 1975-02-25 Warner Lambert Co Heterocyclic amides of 4-hydroxy-2H-1-benzothiopyran-3-carboxylic acid 1,1-dioxide
CA1305480C (en) * 1987-03-20 1992-07-21 Roshantha A.S. Chandraratna Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
US5045551A (en) * 1989-09-19 1991-09-03 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5023341A (en) * 1989-09-19 1991-06-11 Allergan, Inc. Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity

Also Published As

Publication number Publication date
EP0555235A4 (en) 1993-11-10
PT99189A (en) 1992-09-30
FI931624A0 (en) 1993-04-08
CA2091763A1 (en) 1992-04-10
IE913568A1 (en) 1992-04-22
WO1992006092A1 (en) 1992-04-16
ZA918025B (en) 1992-06-24
FI931624A (en) 1993-04-08
HUT63412A (en) 1993-08-30
IL99618A0 (en) 1992-08-18
NZ240059A (en) 1993-10-26
AU8614991A (en) 1992-04-28
AU657100B2 (en) 1995-03-02
JPH06501684A (en) 1994-02-24
EP0555235A1 (en) 1993-08-18
PL168075B1 (en) 1995-12-30

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Legal Events

Date Code Title Description
DFD9 Temporary protection cancelled due to non-payment of fee