HU9301030D0 - An acetylene derivative hqving retinoide-like effect being substituted with phenyl group and chromanyl, thio-chromanyl or tetra-hydro-quinoline one - Google Patents

An acetylene derivative hqving retinoide-like effect being substituted with phenyl group and chromanyl, thio-chromanyl or tetra-hydro-quinoline one

Info

Publication number
HU9301030D0
HU9301030D0 HU931030A HU103093A HU9301030D0 HU 9301030 D0 HU9301030 D0 HU 9301030D0 HU 931030 A HU931030 A HU 931030A HU 103093 A HU103093 A HU 103093A HU 9301030 D0 HU9301030 D0 HU 9301030D0
Authority
HU
Hungary
Prior art keywords
chromanyl
hqving
retinoide
thio
quinoline
Prior art date
Application number
HU931030A
Other languages
Hungarian (hu)
Other versions
HUT63405A (en
Inventor
Roshantha Chandraratna
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of HU9301030D0 publication Critical patent/HU9301030D0/en
Publication of HUT63405A publication Critical patent/HUT63405A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/14—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 6 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU931030A 1990-10-09 1991-09-24 Process for producing acetylene derivatives substituted with chromanyl, thiochromanyl or tetrahydroquinolinyl group and having retinoid-like activity, as well as pharmaceutical compositions comprising same as active ingredient HUT63405A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59488290A 1990-10-09 1990-10-09

Publications (2)

Publication Number Publication Date
HU9301030D0 true HU9301030D0 (en) 1993-07-28
HUT63405A HUT63405A (en) 1993-08-30

Family

ID=24380813

Family Applications (1)

Application Number Title Priority Date Filing Date
HU931030A HUT63405A (en) 1990-10-09 1991-09-24 Process for producing acetylene derivatives substituted with chromanyl, thiochromanyl or tetrahydroquinolinyl group and having retinoid-like activity, as well as pharmaceutical compositions comprising same as active ingredient

Country Status (12)

Country Link
EP (1) EP0553156A4 (en)
JP (1) JPH06501948A (en)
AU (1) AU652189B2 (en)
CA (1) CA2092178A1 (en)
FI (1) FI931625A (en)
HU (1) HUT63405A (en)
IE (1) IE913569A1 (en)
IL (1) IL99617A0 (en)
PL (1) PL168679B1 (en)
PT (1) PT99188A (en)
WO (1) WO1992006084A1 (en)
ZA (1) ZA918026B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69214632T2 (en) * 1991-02-13 1997-05-28 Allergan Inc 7-PHENYLETHYNYL-SUBSTITUTED CHROMANE AND THIOCHROMANE WITH RETINOID-LIKE BIOLOGICAL ACTIVITY
FR2691149B1 (en) * 1992-05-18 1994-07-08 Adir NOVEL THIOCHROMANIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
US5451603A (en) * 1993-03-11 1995-09-19 Zymogenetics, Inc. 3,4-diarylchromans for treatment of dermatitis
NZ331466A (en) 1996-03-18 2000-06-23 Eisai Co Ltd Fused-ring carboxylic acid derivatives
US6740676B2 (en) * 2002-03-19 2004-05-25 Allergan, Inc. 4-[(8-ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-chromanoyl]-benzoic and 2-[4-[(8-ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-chromanoyl]-phenyl]-acetic acid, their esters and salts having cytochrome p450rai inhibitory activity
SG177579A1 (en) 2009-07-16 2012-02-28 Stiefel Laboratories Tazarotene derivatives
CN107176945B (en) * 2016-03-11 2021-06-08 中国科学院上海有机化学研究所 Retinoid compound, preparation method, intermediate and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810804A (en) * 1987-03-26 1989-03-07 Allergan, Inc. Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid-like activity
US4980369A (en) * 1989-09-19 1990-12-25 Allergan, Inc. Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl or thiochromanyl group having retinoid-like activity
DE69214632T2 (en) * 1991-02-13 1997-05-28 Allergan Inc 7-PHENYLETHYNYL-SUBSTITUTED CHROMANE AND THIOCHROMANE WITH RETINOID-LIKE BIOLOGICAL ACTIVITY

Also Published As

Publication number Publication date
PT99188A (en) 1992-09-30
JPH06501948A (en) 1994-03-03
IL99617A0 (en) 1992-08-18
EP0553156A1 (en) 1993-08-04
IE913569A1 (en) 1992-04-22
PL168679B1 (en) 1996-03-29
CA2092178A1 (en) 1992-04-10
WO1992006084A1 (en) 1992-04-16
FI931625A (en) 1993-06-07
HUT63405A (en) 1993-08-30
ZA918026B (en) 1992-06-24
AU8721091A (en) 1992-04-28
FI931625A0 (en) 1993-04-08
AU652189B2 (en) 1994-08-18
EP0553156A4 (en) 1993-11-18

Similar Documents

Publication Publication Date Title
ZA917913B (en) Dripline duct.
YU24390A (en) Substituted 1,3-oxathiolanes with antivirus effect
HU9301536D0 (en) Amino-quinolone derivatives substituted with arylic group or aromatic heterocyclic one
GR3017462T3 (en) 2-Hydroxy-2-phenylethylamine derivatives as beta-3-adrenoceptor agonists.
GR3022463T3 (en) 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives
ZA919660B (en) Alpha-oxoacetamide derivatives.
FI902089A0 (en) APPARAT FOER INDIREKT AVDUNSTNINGSKYLNING AV GAS.
GR3015084T3 (en) Smoking article.
GB2226711B (en) Duct.
FI892350A (en) APPARAT FOER BESTAEMNING AV ROTATIONSPOSITION.
DE69428742T2 (en) Adoptive equalizer
GB9010685D0 (en) I.c.engines
EP0519678A3 (en) 1,4-benzodiazepines with 6-membered heterocyclic rings
AU4456293A (en) 1, 4-Benzodioxane derivatives
HU9301030D0 (en) An acetylene derivative hqving retinoide-like effect being substituted with phenyl group and chromanyl, thio-chromanyl or tetra-hydro-quinoline one
AU8411591A (en) Diphenylurea derivatives
HU9201804D0 (en) Gingerole and gingerdiole derivatives for decreasing cholesterole, with anti-arterosclerosys effect
HU9301031D0 (en) An acetylene derivative hqving retinoide-like effect being substituted with heter-aromatic group and chromanyl, thio-chromanyl or tetra-hydro-quinoline one
EP0482206A4 (en) 4,6-o-hydroxyphosphorylglucosamine derivative
FI891179A0 (en) APPARAT FOER FOERPACKNING AV MJUKT TUGGUMMI.
AU1633995A (en) 1,4-diamino-2,3-dihydroxybutanes
HU908313D0 (en) New 15-nitro-2betha, 3betha-dihydro- and 15-nitro-2betha, 3 betha,6,7-tetrahydro-tabersonine derivatives
AU7073291A (en) Hypervelocity drag reduction
ZA925324B (en) Decahydro-8h-isoquino Ú2,1-g¾ Ú1,6¾naphthyridine and decahydrobenzo Úa¾pyrrolo Ú2,3-e¾quinolizine derivatives
AU8298191A (en) System for oriented strand layup

Legal Events

Date Code Title Description
DFD9 Temporary protection cancelled due to non-payment of fee