FI931625A - Chromans and thiochromers with retinoid activity - Google Patents

Chromans and thiochromers with retinoid activity Download PDF

Info

Publication number
FI931625A
FI931625A FI931625A FI931625A FI931625A FI 931625 A FI931625 A FI 931625A FI 931625 A FI931625 A FI 931625A FI 931625 A FI931625 A FI 931625A FI 931625 A FI931625 A FI 931625A
Authority
FI
Finland
Prior art keywords
thiochromers
chromans
retinoid activity
retinoid
activity
Prior art date
Application number
FI931625A
Other languages
Finnish (fi)
Other versions
FI931625A0 (en
Inventor
Roshantha A S Chandraratna
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of FI931625A0 publication Critical patent/FI931625A0/en
Publication of FI931625A publication Critical patent/FI931625A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/14—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 6 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI931625A 1990-10-09 1993-04-08 Chromans and thiochromers with retinoid activity FI931625A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59488290A 1990-10-09 1990-10-09
PCT/US1991/006901 WO1992006084A1 (en) 1990-10-09 1991-09-24 Chromans and thiochromans with retinoid-like activity

Publications (2)

Publication Number Publication Date
FI931625A0 FI931625A0 (en) 1993-04-08
FI931625A true FI931625A (en) 1993-06-07

Family

ID=24380813

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931625A FI931625A (en) 1990-10-09 1993-04-08 Chromans and thiochromers with retinoid activity

Country Status (12)

Country Link
EP (1) EP0553156A4 (en)
JP (1) JPH06501948A (en)
AU (1) AU652189B2 (en)
CA (1) CA2092178A1 (en)
FI (1) FI931625A (en)
HU (1) HUT63405A (en)
IE (1) IE913569A1 (en)
IL (1) IL99617A0 (en)
PL (1) PL168679B1 (en)
PT (1) PT99188A (en)
WO (1) WO1992006084A1 (en)
ZA (1) ZA918026B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69214632T2 (en) * 1991-02-13 1997-05-28 Allergan Inc 7-PHENYLETHYNYL-SUBSTITUTED CHROMANE AND THIOCHROMANE WITH RETINOID-LIKE BIOLOGICAL ACTIVITY
FR2691149B1 (en) * 1992-05-18 1994-07-08 Adir NOVEL THIOCHROMANIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
US5451603A (en) * 1993-03-11 1995-09-19 Zymogenetics, Inc. 3,4-diarylchromans for treatment of dermatitis
NZ331466A (en) 1996-03-18 2000-06-23 Eisai Co Ltd Fused-ring carboxylic acid derivatives
US6740676B2 (en) * 2002-03-19 2004-05-25 Allergan, Inc. 4-[(8-ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-chromanoyl]-benzoic and 2-[4-[(8-ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-chromanoyl]-phenyl]-acetic acid, their esters and salts having cytochrome p450rai inhibitory activity
SG177579A1 (en) 2009-07-16 2012-02-28 Stiefel Laboratories Tazarotene derivatives
CN107176945B (en) * 2016-03-11 2021-06-08 中国科学院上海有机化学研究所 Retinoid compound, preparation method, intermediate and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810804A (en) * 1987-03-26 1989-03-07 Allergan, Inc. Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid-like activity
US4980369A (en) * 1989-09-19 1990-12-25 Allergan, Inc. Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl or thiochromanyl group having retinoid-like activity
DE69214632T2 (en) * 1991-02-13 1997-05-28 Allergan Inc 7-PHENYLETHYNYL-SUBSTITUTED CHROMANE AND THIOCHROMANE WITH RETINOID-LIKE BIOLOGICAL ACTIVITY

Also Published As

Publication number Publication date
PT99188A (en) 1992-09-30
JPH06501948A (en) 1994-03-03
IL99617A0 (en) 1992-08-18
EP0553156A1 (en) 1993-08-04
IE913569A1 (en) 1992-04-22
PL168679B1 (en) 1996-03-29
HU9301030D0 (en) 1993-07-28
CA2092178A1 (en) 1992-04-10
WO1992006084A1 (en) 1992-04-16
HUT63405A (en) 1993-08-30
ZA918026B (en) 1992-06-24
AU8721091A (en) 1992-04-28
FI931625A0 (en) 1993-04-08
AU652189B2 (en) 1994-08-18
EP0553156A4 (en) 1993-11-18

Similar Documents

Publication Publication Date Title
BR9101311A (en) DIAPER
BR8901524A (en) DISPOSABLE ABSORBENT ITEM
DK104091A (en) Absorptive
DE59108611D1 (en) Picolin oxides
FI932114A0 (en) Maolspecifika erythrocytes and thromboerytrocytes
BR9100157A (en) ABSORBENT STRUCTURE AND METHOD OF DOING THE SAME
FI923352A (en) FLUORELASTOMERA BLANDPOLYMER MODIFIED WITH PERFLUORALKYLVINYLETTER OCH BASERADE PAO VINYLIDENFLUORID
BR8902476A (en) ABSORBENT STRUCTURE AND ABSORBENT PRODUCT
FI931625A (en) Chromans and thiochromers with retinoid activity
DK89991A (en) Absorbent disposable item
TR25296A (en) COMBINATIONS WITH FUNGUSID ACTIVITY
TR25733A (en) COMBINATIONS WITH FUNGUSID ACTIVITY
NO914343D0 (en) MARIN CONSTRUCTION
NO914486L (en) MARIN CONSTRUCTION
FI960342A0 (en) Benzoxazinones and benzothiazinones with therapeutic activity
DK124390D0 (en) PROSTAGLAND INERIVATIVES WITH ANTITHROMOBOTIC EFFECT
SE8902995L (en) STEPS AND STEPS
DK179288A (en) DIOXOLAN AND DIOXANDER DERIVATIVES
FI88480C (en) gantry
SE8900412D0 (en) SAID TO PREPARE SKIN AND SKIN
SE8800855D0 (en) MOUNTING AND REMOVABLE MOVING FABRIC
KR920007433U (en) Skin tights
BR9002261A (en) THERMOKIT-HEATER AND MICROSECADER
SE8803040D0 (en) NERINGS AND YOUTH IMPROVEMENT AGENTS
SE8802976D0 (en) DOUBLE AND SINGLE RAILWAY

Legal Events

Date Code Title Description
FD Application lapsed