NZ240059A - Acetylenes disubstituted with heteroaromatic group and a 2-substituted chromanyl, thiochromanyl, or 1,2,3,4-tetrahydroquinolinyl group; pharmaceutical compositions and preparatory processes - Google Patents

Acetylenes disubstituted with heteroaromatic group and a 2-substituted chromanyl, thiochromanyl, or 1,2,3,4-tetrahydroquinolinyl group; pharmaceutical compositions and preparatory processes

Info

Publication number
NZ240059A
NZ240059A NZ240059A NZ24005991A NZ240059A NZ 240059 A NZ240059 A NZ 240059A NZ 240059 A NZ240059 A NZ 240059A NZ 24005991 A NZ24005991 A NZ 24005991A NZ 240059 A NZ240059 A NZ 240059A
Authority
NZ
New Zealand
Prior art keywords
group
thiochromanyl
pharmaceutical compositions
tetrahydroquinolinyl
preparatory processes
Prior art date
Application number
NZ240059A
Other languages
English (en)
Inventor
A S Chandraratna Roshantha
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of NZ240059A publication Critical patent/NZ240059A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NZ240059A 1990-10-09 1991-10-01 Acetylenes disubstituted with heteroaromatic group and a 2-substituted chromanyl, thiochromanyl, or 1,2,3,4-tetrahydroquinolinyl group; pharmaceutical compositions and preparatory processes NZ240059A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59512890A 1990-10-09 1990-10-09

Publications (1)

Publication Number Publication Date
NZ240059A true NZ240059A (en) 1993-10-26

Family

ID=24381853

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ240059A NZ240059A (en) 1990-10-09 1991-10-01 Acetylenes disubstituted with heteroaromatic group and a 2-substituted chromanyl, thiochromanyl, or 1,2,3,4-tetrahydroquinolinyl group; pharmaceutical compositions and preparatory processes

Country Status (13)

Country Link
EP (1) EP0555235A4 (xx)
JP (1) JPH06501684A (xx)
AU (1) AU657100B2 (xx)
CA (1) CA2091763A1 (xx)
FI (1) FI931624A0 (xx)
HU (1) HUT63412A (xx)
IE (1) IE913568A1 (xx)
IL (1) IL99618A0 (xx)
NZ (1) NZ240059A (xx)
PL (1) PL168075B1 (xx)
PT (1) PT99189A (xx)
WO (1) WO1992006092A1 (xx)
ZA (1) ZA918025B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5602130A (en) * 1987-03-20 1997-02-11 Allergan Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
US7452911B2 (en) 2002-10-31 2008-11-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
CN107176945B (zh) * 2016-03-11 2021-06-08 中国科学院上海有机化学研究所 一种视黄酸类化合物、其制备方法、中间体及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3816466A (en) * 1971-12-22 1974-06-11 Warner Lambert Co Flavanoid ring systems
US3868379A (en) * 1972-04-28 1975-02-25 Warner Lambert Co Heterocyclic amides of 4-hydroxy-2H-1-benzothiopyran-3-carboxylic acid 1,1-dioxide
CA1305480C (en) * 1987-03-20 1992-07-21 Roshantha A.S. Chandraratna Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
US5045551A (en) * 1989-09-19 1991-09-03 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5023341A (en) * 1989-09-19 1991-06-11 Allergan, Inc. Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity

Also Published As

Publication number Publication date
CA2091763A1 (en) 1992-04-10
IE913568A1 (en) 1992-04-22
EP0555235A4 (en) 1993-11-10
AU8614991A (en) 1992-04-28
ZA918025B (en) 1992-06-24
FI931624A (fi) 1993-04-08
IL99618A0 (en) 1992-08-18
EP0555235A1 (en) 1993-08-18
PL168075B1 (pl) 1995-12-30
AU657100B2 (en) 1995-03-02
HU9301031D0 (en) 1993-07-28
JPH06501684A (ja) 1994-02-24
HUT63412A (en) 1993-08-30
PT99189A (pt) 1992-09-30
FI931624A0 (fi) 1993-04-08
WO1992006092A1 (en) 1992-04-16

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