FI931624A0 - Acetylener disubstituerade med en heteroaromatisk grupp och en 2-substituerad kromanyl, tiokromanyl eller 1,2,3,4-tetrahydrokinolinylgrupp med retinoid-lik aktivitet - Google Patents

Acetylener disubstituerade med en heteroaromatisk grupp och en 2-substituerad kromanyl, tiokromanyl eller 1,2,3,4-tetrahydrokinolinylgrupp med retinoid-lik aktivitet

Info

Publication number
FI931624A0
FI931624A0 FI931624A FI931624A FI931624A0 FI 931624 A0 FI931624 A0 FI 931624A0 FI 931624 A FI931624 A FI 931624A FI 931624 A FI931624 A FI 931624A FI 931624 A0 FI931624 A0 FI 931624A0
Authority
FI
Finland
Prior art keywords
med
tiokromanyl
tetrahydrokinolinygrupp
kromanyl
heteroaromatisk
Prior art date
Application number
FI931624A
Other languages
English (en)
Finnish (fi)
Other versions
FI931624A (fi
Inventor
Roshantha A S Chandraratna
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of FI931624A0 publication Critical patent/FI931624A0/fi
Publication of FI931624A publication Critical patent/FI931624A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI931624A 1990-10-09 1993-04-08 Acetylener disubstituerade med en heteroaromatisk grupp och en 2-substituerad kromanyl, tiokromanyl eller 1,2,3,4-tetrahydrokinolinylgrupp med retinoid-lik aktivitet FI931624A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59512890A 1990-10-09 1990-10-09
PCT/US1991/006900 WO1992006092A1 (en) 1990-10-09 1991-09-24 Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity

Publications (2)

Publication Number Publication Date
FI931624A0 true FI931624A0 (fi) 1993-04-08
FI931624A FI931624A (fi) 1993-04-08

Family

ID=24381853

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931624A FI931624A (fi) 1990-10-09 1993-04-08 Acetylener disubstituerade med en heteroaromatisk grupp och en 2-substituerad kromanyl, tiokromanyl eller 1,2,3,4-tetrahydrokinolinylgrupp med retinoid-lik aktivitet

Country Status (13)

Country Link
EP (1) EP0555235A4 (hu)
JP (1) JPH06501684A (hu)
AU (1) AU657100B2 (hu)
CA (1) CA2091763A1 (hu)
FI (1) FI931624A (hu)
HU (1) HUT63412A (hu)
IE (1) IE913568A1 (hu)
IL (1) IL99618A0 (hu)
NZ (1) NZ240059A (hu)
PL (1) PL168075B1 (hu)
PT (1) PT99189A (hu)
WO (1) WO1992006092A1 (hu)
ZA (1) ZA918025B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5602130A (en) * 1987-03-20 1997-02-11 Allergan Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
US7452911B2 (en) 2002-10-31 2008-11-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
CN107176945B (zh) 2016-03-11 2021-06-08 中国科学院上海有机化学研究所 一种视黄酸类化合物、其制备方法、中间体及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3816466A (en) * 1971-12-22 1974-06-11 Warner Lambert Co Flavanoid ring systems
US3868379A (en) * 1972-04-28 1975-02-25 Warner Lambert Co Heterocyclic amides of 4-hydroxy-2H-1-benzothiopyran-3-carboxylic acid 1,1-dioxide
CA1305480C (en) * 1987-03-20 1992-07-21 Roshantha A.S. Chandraratna Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
US5023341A (en) * 1989-09-19 1991-06-11 Allergan, Inc. Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity
US5045551A (en) * 1989-09-19 1991-09-03 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity

Also Published As

Publication number Publication date
HUT63412A (en) 1993-08-30
JPH06501684A (ja) 1994-02-24
PL168075B1 (pl) 1995-12-30
HU9301031D0 (en) 1993-07-28
CA2091763A1 (en) 1992-04-10
AU657100B2 (en) 1995-03-02
WO1992006092A1 (en) 1992-04-16
EP0555235A1 (en) 1993-08-18
IL99618A0 (en) 1992-08-18
FI931624A (fi) 1993-04-08
IE913568A1 (en) 1992-04-22
EP0555235A4 (en) 1993-11-10
PT99189A (pt) 1992-09-30
AU8614991A (en) 1992-04-28
NZ240059A (en) 1993-10-26
ZA918025B (en) 1992-06-24

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Legal Events

Date Code Title Description
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