ZA915595B - Carbostyril derivatives - Google Patents

Carbostyril derivatives

Info

Publication number
ZA915595B
ZA915595B ZA915595A ZA915595A ZA915595B ZA 915595 B ZA915595 B ZA 915595B ZA 915595 A ZA915595 A ZA 915595A ZA 915595 A ZA915595 A ZA 915595A ZA 915595 B ZA915595 B ZA 915595B
Authority
ZA
South Africa
Prior art keywords
carbostyril derivatives
carbostyril
derivatives
Prior art date
Application number
ZA915595A
Other languages
English (en)
Inventor
Jean-Claude Pascal
Pascal Jean-Claude
Leslie Patmore
Patmore Leslie
Jurg R Pfister
R Pfister Jurg
Dominique Blondet
Blondet Dominique
John Michael Armstrong
Michael Armstrong John
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of ZA915595B publication Critical patent/ZA915595B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA915595A 1990-07-18 1991-07-17 Carbostyril derivatives ZA915595B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/555,201 US5082847A (en) 1990-07-18 1990-07-18 Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility

Publications (1)

Publication Number Publication Date
ZA915595B true ZA915595B (en) 1993-03-31

Family

ID=24216365

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA915595A ZA915595B (en) 1990-07-18 1991-07-17 Carbostyril derivatives

Country Status (15)

Country Link
US (1) US5082847A (xx)
EP (1) EP0467325A3 (xx)
JP (1) JPH04234386A (xx)
KR (1) KR920002580A (xx)
AU (1) AU648090B2 (xx)
CA (1) CA2047307A1 (xx)
FI (1) FI913450A (xx)
HU (1) HUT58316A (xx)
IE (1) IE912499A1 (xx)
IL (1) IL98863A0 (xx)
IT (1) IT1252602B (xx)
MX (1) MX9100225A (xx)
NO (1) NO912797L (xx)
PT (1) PT98350A (xx)
ZA (1) ZA915595B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993023386A1 (en) * 1992-05-15 1993-11-25 Mitsui Toatsu Chemicals, Incorporated Process for producing glycide derivative
IL106549A0 (en) * 1992-07-31 1993-12-08 Syntex Inc Heterocyclic derivatives,their preparation and pharmaceutical compositions containing them
IT1264816B1 (it) * 1993-07-28 1996-10-10 Pergam Srl Procedimento per la preparazione di derivati del procedimento per la preparazione di derivati del 3,4-diidrocarbostirile 3,4-diidrocarbostirile
TW436483B (en) * 1997-08-19 2001-05-28 Otsuka Pharma Co Ltd Carbostyril derivatives, process for their preparation and pharmaceutical composition or cosmetic composition for inhibiting skin erythema and/or skin pigmentation
US6140349A (en) 1998-02-02 2000-10-31 Merck & Co., Inc. Cyclic amine modulators of chemokine receptor activity
EP1147772B1 (en) 1998-12-28 2006-01-04 Noboru Kaneko Use of 1,4-benzothiazepine derivatives for the preparation of a medicament FOR the TREATMENT OF ATRIAL FIBRILLATION
US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US7718644B2 (en) 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
US7879840B2 (en) 2005-08-25 2011-02-01 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US8710045B2 (en) 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
US7704990B2 (en) 2005-08-25 2010-04-27 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
DE102006039038A1 (de) * 2006-08-19 2008-02-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neues Herstellungsverfahren
TWI498115B (zh) * 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd 咪唑羰基化合物
TWI679205B (zh) 2014-09-02 2019-12-11 日商日本新藥股份有限公司 吡唑并噻唑化合物及醫藥

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5310986B2 (xx) * 1974-02-05 1978-04-18
JPS5310989B2 (xx) * 1974-04-25 1978-04-18
JPS5936617B2 (ja) * 1976-03-05 1984-09-05 大塚製薬株式会社 カルボスチリル誘導体
US4210753A (en) * 1976-03-17 1980-07-01 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds
JPS5589221A (en) * 1978-12-28 1980-07-05 Otsuka Pharmaceut Co Ltd Antihistaminic agent
DE2901336A1 (de) * 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE2905876A1 (de) * 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue piperidinopropylderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3034237A1 (de) * 1979-09-18 1981-04-16 Otsuka Pharmaceutical Co. Ltd., Tokyo Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel
JPS5718674A (en) * 1980-07-07 1982-01-30 Otsuka Pharmaceut Co Ltd Carbostyril derivative
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
JPS63290821A (ja) * 1987-05-25 1988-11-28 Otsuka Pharmaceut Co Ltd 抗不整脈剤
NZ225152A (en) * 1987-07-17 1990-04-26 Janssen Pharmaceutica Nv Heterocyclically substituted piperidinyl benzamides as pharmaceuticals
MX13485A (es) * 1987-10-19 1993-05-01 Pfizer Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos
IT1223395B (it) * 1987-12-01 1990-09-19 Simes Composti ad attivita' cardiovascolare
EP0355583B1 (en) * 1988-08-10 1995-01-25 Otsuka Pharmaceutical Co., Ltd. Cardiotonics

Also Published As

Publication number Publication date
AU648090B2 (en) 1994-04-14
IL98863A0 (en) 1992-07-15
FI913450A0 (fi) 1991-07-17
MX9100225A (es) 1992-02-28
HU912390D0 (en) 1991-12-30
EP0467325A2 (en) 1992-01-22
IT1252602B (it) 1995-06-19
JPH04234386A (ja) 1992-08-24
ITTO910567A0 (it) 1991-07-17
US5082847A (en) 1992-01-21
NO912797L (no) 1992-01-20
CA2047307A1 (en) 1992-01-19
NO912797D0 (no) 1991-07-17
KR920002580A (ko) 1992-02-28
AU8046191A (en) 1992-01-23
EP0467325A3 (en) 1992-05-06
HUT58316A (en) 1992-02-28
FI913450A (fi) 1992-01-19
IE912499A1 (en) 1992-01-29
ITTO910567A1 (it) 1993-01-17
PT98350A (pt) 1992-05-29

Similar Documents

Publication Publication Date Title
KR970011153B1 (en) Carbostyril derivatives
EP0440950A3 (en) Halogenallyl-azolyl derivatives
HU912356D0 (en) Rapacmycine derivatives
SG44523A1 (en) Quinoline derivatives
EP0470466A3 (en) Halogenalkyl-azolyl derivatives
ZA914484B (en) Azolyl-propanol derivatives
IL96819A0 (en) Azaoxindole derivatives
HRP930485A2 (en) Hiv-inhibiting benzenacetamide derivatives
IL99576A0 (en) Triazacyclohexane derivatives
ZA915595B (en) Carbostyril derivatives
ZA914204B (en) Pyridinylpiperazine derivatives
EP0485984A3 (en) Diarylmethoxypiperidine derivatives
OA09670A (en) Carbo-nucleoside derivatives
EP0440949A3 (en) Halogenallyl-azolyl derivatives
ZA914675B (en) 5-isothiazolamine derivatives
IL98897A0 (en) Carboxymethylcyclopropane derivatives
EP0453883A3 (en) 2-amino-4-trichloropyridine derivatives
GB2249094B (en) Hetero-imidazodiazepine derivatives
GB9006772D0 (en) 4-piperidinyl-ergoline derivatives
IE901869L (en) Quinoline derivatives
IE900817L (en) Tetrahydroquinoline derivatives
EG19474A (en) Nitroenamine derivatives
EG19362A (en) Azoaxindole derivatives
GB9008119D0 (en) Dehydro-oxathiazinone derivatives
IE901472L (en) Phodomycin derivatives