NO912797D0 - Analogifremgangsmaate for fremstilling av terapeutisk virksomme karbostirilderivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk virksomme karbostirilderivater.

Info

Publication number
NO912797D0
NO912797D0 NO912797A NO912797A NO912797D0 NO 912797 D0 NO912797 D0 NO 912797D0 NO 912797 A NO912797 A NO 912797A NO 912797 A NO912797 A NO 912797A NO 912797 D0 NO912797 D0 NO 912797D0
Authority
NO
Norway
Prior art keywords
carbostiril
derivatives
preparation
therapeutically effective
analogy procedure
Prior art date
Application number
NO912797A
Other languages
English (en)
Other versions
NO912797L (no
Inventor
Jean-Claude Pascal
Leslie Patmore
Jurg Pfister
Dominique Blondet
John Michael Armstrong
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of NO912797D0 publication Critical patent/NO912797D0/no
Publication of NO912797L publication Critical patent/NO912797L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO91912797A 1990-07-18 1991-07-17 Analogifremgangsmaate for fremstilling av terapeutisk virksomme karbostirilderivater. NO912797L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/555,201 US5082847A (en) 1990-07-18 1990-07-18 Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility

Publications (2)

Publication Number Publication Date
NO912797D0 true NO912797D0 (no) 1991-07-17
NO912797L NO912797L (no) 1992-01-20

Family

ID=24216365

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91912797A NO912797L (no) 1990-07-18 1991-07-17 Analogifremgangsmaate for fremstilling av terapeutisk virksomme karbostirilderivater.

Country Status (15)

Country Link
US (1) US5082847A (no)
EP (1) EP0467325A3 (no)
JP (1) JPH04234386A (no)
KR (1) KR920002580A (no)
AU (1) AU648090B2 (no)
CA (1) CA2047307A1 (no)
FI (1) FI913450A (no)
HU (1) HUT58316A (no)
IE (1) IE912499A1 (no)
IL (1) IL98863A0 (no)
IT (1) IT1252602B (no)
MX (1) MX9100225A (no)
NO (1) NO912797L (no)
PT (1) PT98350A (no)
ZA (1) ZA915595B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0603404B1 (en) * 1992-05-15 1999-03-17 Mitsui Chemicals, Inc. Process for producing glycide derivative
MX9304626A (es) * 1992-07-31 1994-02-28 Syntex Inc Derivados heterociclicos utiles en el tratamiento de enfermedades cardiovasculares.
IT1264816B1 (it) * 1993-07-28 1996-10-10 Pergam Srl Procedimento per la preparazione di derivati del procedimento per la preparazione di derivati del 3,4-diidrocarbostirile 3,4-diidrocarbostirile
TW436483B (en) * 1997-08-19 2001-05-28 Otsuka Pharma Co Ltd Carbostyril derivatives, process for their preparation and pharmaceutical composition or cosmetic composition for inhibiting skin erythema and/or skin pigmentation
US6140349A (en) * 1998-02-02 2000-10-31 Merck & Co., Inc. Cyclic amine modulators of chemokine receptor activity
CA2357038C (en) * 1998-12-28 2008-10-21 Japan Tobacco Inc. Medical compositions comprising 1,4-benzothiazepine derivatives for the treatment of atrial fibrillation
US7718644B2 (en) 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
US7879840B2 (en) 2005-08-25 2011-02-01 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US8710045B2 (en) 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
US7704990B2 (en) 2005-08-25 2010-04-27 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
DE102006039038A1 (de) * 2006-08-19 2008-02-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neues Herstellungsverfahren
TWI498115B (zh) * 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd 咪唑羰基化合物
TWI679205B (zh) 2014-09-02 2019-12-11 日商日本新藥股份有限公司 吡唑并噻唑化合物及醫藥

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5310986B2 (no) * 1974-02-05 1978-04-18
JPS5310989B2 (no) * 1974-04-25 1978-04-18
JPS5936617B2 (ja) * 1976-03-05 1984-09-05 大塚製薬株式会社 カルボスチリル誘導体
US4210753A (en) * 1976-03-17 1980-07-01 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds
JPS5589221A (en) * 1978-12-28 1980-07-05 Otsuka Pharmaceut Co Ltd Antihistaminic agent
DE2901336A1 (de) * 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE2905876A1 (de) * 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue piperidinopropylderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3034237A1 (de) * 1979-09-18 1981-04-16 Otsuka Pharmaceutical Co. Ltd., Tokyo Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel
JPS5718674A (en) * 1980-07-07 1982-01-30 Otsuka Pharmaceut Co Ltd Carbostyril derivative
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
JPS63290821A (ja) * 1987-05-25 1988-11-28 Otsuka Pharmaceut Co Ltd 抗不整脈剤
NZ225152A (en) * 1987-07-17 1990-04-26 Janssen Pharmaceutica Nv Heterocyclically substituted piperidinyl benzamides as pharmaceuticals
MX13485A (es) * 1987-10-19 1993-05-01 Pfizer Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos
IT1223395B (it) * 1987-12-01 1990-09-19 Simes Composti ad attivita' cardiovascolare
US5053514A (en) * 1988-08-10 1991-10-01 Otsuka Pharmaceutical Company, Limited Cardiotonics

Also Published As

Publication number Publication date
NO912797L (no) 1992-01-20
US5082847A (en) 1992-01-21
JPH04234386A (ja) 1992-08-24
EP0467325A3 (en) 1992-05-06
IT1252602B (it) 1995-06-19
PT98350A (pt) 1992-05-29
KR920002580A (ko) 1992-02-28
HU912390D0 (en) 1991-12-30
CA2047307A1 (en) 1992-01-19
HUT58316A (en) 1992-02-28
FI913450A (fi) 1992-01-19
AU648090B2 (en) 1994-04-14
EP0467325A2 (en) 1992-01-22
ITTO910567A1 (it) 1993-01-17
IE912499A1 (en) 1992-01-29
IL98863A0 (en) 1992-07-15
MX9100225A (es) 1992-02-28
ITTO910567A0 (it) 1991-07-17
AU8046191A (en) 1992-01-23
FI913450A0 (fi) 1991-07-17
ZA915595B (en) 1993-03-31

Similar Documents

Publication Publication Date Title
NO913234D0 (no) Fremgangsmaate for fremstilling av pyrazolderivater.
NO914825D0 (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme alfa-oxoacetamider
NO910395D0 (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme 4-isoxazolcarboxamidderivater.
NO912051L (no) Fremgangsmaate for fremstilling av azolderivater.
NO911591D0 (no) Fremgangsmaate for fremstilling av sukrose-6-ester.
NO912411D0 (no) Fremgangsmaate for fremstilling av bicykliske heterocykliske forbindelser.
NO912346D0 (no) Fremgangsmaate for fremstilling av aminobenzodiazepiner.
NO911122D0 (no) Fremgangsmaate for fremstilling av antihyperkolesterolemiske midler.
NO912797D0 (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme karbostirilderivater.
NO911065D0 (no) Fremgangsmaate for fremstilling av lipopeptidderivater.
NO156865C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme imidazolderivater.
NO914053L (no) Fremgangsmaate for fremstilling av 8-klorokinolonderivater
NO913692D0 (no) Fremgangsmaate for fremstilling av karbapenemforbindelser.
NO304428B1 (no) AnalogifremgangsmÕte for fremstilling av terapeutisk aktive vinylazoler
NO157736C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme imidazolderivater.
NO903397D0 (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme derivater av protocatechualdehyd.
NO912979D0 (no) Fremgangsmaate for fremstilling av 2-(9-fluorenoyl)-carbapenederivater.
NO914985D0 (no) Fremgangsmaate for fremstilling av 15-nitro-tabersonin-derivater
NO911672D0 (no) Fremgangsmaate for fremstilling av alkansulfonanilid-derivater.
NO914452D0 (no) Fremgangsmaate for fremstilling av isokinolinderivater
NO904678D0 (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme benzylpyrrolidenderivater.
NO169337C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme nafthalenderivater.
NO173140C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tieno-triazolo-diazepin-derivater
NO913429D0 (no) Fremgangsmaate for fremstilling av 5-benzyl-substituerte benzimidazolin-2-tion-derivater.
FI913414A0 (fi) Foerfarande foer framstaellning av 2-hydroxi-3-halogen-5-nitropyridiner.