ITTO910567A1 - Derivati carbostirilici. - Google Patents

Derivati carbostirilici.

Info

Publication number
ITTO910567A1
ITTO910567A1 IT000567A ITTO910567A ITTO910567A1 IT TO910567 A1 ITTO910567 A1 IT TO910567A1 IT 000567 A IT000567 A IT 000567A IT TO910567 A ITTO910567 A IT TO910567A IT TO910567 A1 ITTO910567 A1 IT TO910567A1
Authority
IT
Italy
Prior art keywords
carbostyrilic
derivatives
carbostyrilic derivatives
Prior art date
Application number
IT000567A
Other languages
English (en)
Inventor
Jhonn Michael Armostrong
Dominique Blondet
Jean-Claud Pascal
Leslie Patmore
Jurg Pfister
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of ITTO910567A0 publication Critical patent/ITTO910567A0/it
Publication of ITTO910567A1 publication Critical patent/ITTO910567A1/it
Application granted granted Critical
Publication of IT1252602B publication Critical patent/IT1252602B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ITTO910567A 1990-07-18 1991-07-17 Derivati carbostirilici. IT1252602B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/555,201 US5082847A (en) 1990-07-18 1990-07-18 Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility

Publications (3)

Publication Number Publication Date
ITTO910567A0 ITTO910567A0 (it) 1991-07-17
ITTO910567A1 true ITTO910567A1 (it) 1993-01-17
IT1252602B IT1252602B (it) 1995-06-19

Family

ID=24216365

Family Applications (1)

Application Number Title Priority Date Filing Date
ITTO910567A IT1252602B (it) 1990-07-18 1991-07-17 Derivati carbostirilici.

Country Status (15)

Country Link
US (1) US5082847A (it)
EP (1) EP0467325A3 (it)
JP (1) JPH04234386A (it)
KR (1) KR920002580A (it)
AU (1) AU648090B2 (it)
CA (1) CA2047307A1 (it)
FI (1) FI913450A (it)
HU (1) HUT58316A (it)
IE (1) IE912499A1 (it)
IL (1) IL98863A0 (it)
IT (1) IT1252602B (it)
MX (1) MX9100225A (it)
NO (1) NO912797L (it)
PT (1) PT98350A (it)
ZA (1) ZA915595B (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69323970T2 (de) * 1992-05-15 1999-10-07 Mitsui Chemicals Inc Verfahren zur herstellung von glycidderivaten
AU4787593A (en) * 1992-07-31 1994-03-03 Syntex (U.S.A.) Inc. Heterocyclic derivatives useful in the treatment of cardiovascular diseases
IT1264816B1 (it) * 1993-07-28 1996-10-10 Pergam Srl Procedimento per la preparazione di derivati del procedimento per la preparazione di derivati del 3,4-diidrocarbostirile 3,4-diidrocarbostirile
TW436483B (en) * 1997-08-19 2001-05-28 Otsuka Pharma Co Ltd Carbostyril derivatives, process for their preparation and pharmaceutical composition or cosmetic composition for inhibiting skin erythema and/or skin pigmentation
US6140349A (en) * 1998-02-02 2000-10-31 Merck & Co., Inc. Cyclic amine modulators of chemokine receptor activity
DE69929362T2 (de) 1998-12-28 2006-09-28 Kaneko, Noboru verwendung von 1,4-benzothiazepinen zur Herstellung eines Medikaments ZUR BEHANDLUNG DER VORHOF-FIBRILLATION
US7879840B2 (en) 2005-08-25 2011-02-01 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US7718644B2 (en) 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
US8710045B2 (en) 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
US7704990B2 (en) 2005-08-25 2010-04-27 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
DE102006039038A1 (de) * 2006-08-19 2008-02-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neues Herstellungsverfahren
TWI498115B (zh) 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd 咪唑羰基化合物
TWI679205B (zh) 2014-09-02 2019-12-11 日商日本新藥股份有限公司 吡唑并噻唑化合物及醫藥

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5310986B2 (it) * 1974-02-05 1978-04-18
JPS5310989B2 (it) * 1974-04-25 1978-04-18
JPS5936617B2 (ja) * 1976-03-05 1984-09-05 大塚製薬株式会社 カルボスチリル誘導体
US4210753A (en) * 1976-03-17 1980-07-01 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds
JPS5589221A (en) * 1978-12-28 1980-07-05 Otsuka Pharmaceut Co Ltd Antihistaminic agent
DE2901336A1 (de) * 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE2905876A1 (de) * 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue piperidinopropylderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3034237A1 (de) * 1979-09-18 1981-04-16 Otsuka Pharmaceutical Co. Ltd., Tokyo Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel
JPS5718674A (en) * 1980-07-07 1982-01-30 Otsuka Pharmaceut Co Ltd Carbostyril derivative
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
JPS63290821A (ja) * 1987-05-25 1988-11-28 Otsuka Pharmaceut Co Ltd 抗不整脈剤
NZ225152A (en) * 1987-07-17 1990-04-26 Janssen Pharmaceutica Nv Heterocyclically substituted piperidinyl benzamides as pharmaceuticals
MX13485A (es) * 1987-10-19 1993-05-01 Pfizer Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos
IT1223395B (it) * 1987-12-01 1990-09-19 Simes Composti ad attivita' cardiovascolare
EP0355583B1 (en) * 1988-08-10 1995-01-25 Otsuka Pharmaceutical Co., Ltd. Cardiotonics

Also Published As

Publication number Publication date
NO912797L (no) 1992-01-20
FI913450A (fi) 1992-01-19
ITTO910567A0 (it) 1991-07-17
EP0467325A2 (en) 1992-01-22
CA2047307A1 (en) 1992-01-19
IE912499A1 (en) 1992-01-29
IT1252602B (it) 1995-06-19
FI913450A0 (fi) 1991-07-17
EP0467325A3 (en) 1992-05-06
PT98350A (pt) 1992-05-29
AU8046191A (en) 1992-01-23
HUT58316A (en) 1992-02-28
JPH04234386A (ja) 1992-08-24
US5082847A (en) 1992-01-21
ZA915595B (en) 1993-03-31
MX9100225A (es) 1992-02-28
HU912390D0 (en) 1991-12-30
AU648090B2 (en) 1994-04-14
KR920002580A (ko) 1992-02-28
IL98863A0 (en) 1992-07-15
NO912797D0 (no) 1991-07-17

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Legal Events

Date Code Title Description
0001 Granted