ZA913546B - Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof - Google Patents
Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereofInfo
- Publication number
- ZA913546B ZA913546B ZA913546A ZA913546A ZA913546B ZA 913546 B ZA913546 B ZA 913546B ZA 913546 A ZA913546 A ZA 913546A ZA 913546 A ZA913546 A ZA 913546A ZA 913546 B ZA913546 B ZA 913546B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- alkoxy
- derivatives
- hydrogen
- carboxylic acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/521,777 US5073562A (en) | 1990-05-10 | 1990-05-10 | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA913546B true ZA913546B (en) | 1992-07-29 |
Family
ID=24078110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA913546A ZA913546B (en) | 1990-05-10 | 1991-05-10 | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5073562A (xx) |
| EP (1) | EP0527922B1 (xx) |
| JP (1) | JPH05507084A (xx) |
| AT (1) | ATE119528T1 (xx) |
| AU (1) | AU647487B2 (xx) |
| CA (1) | CA2082500A1 (xx) |
| DE (1) | DE69108025T2 (xx) |
| DK (1) | DK0527922T3 (xx) |
| ES (1) | ES2069295T3 (xx) |
| GR (1) | GR3015349T3 (xx) |
| IE (1) | IE62719B1 (xx) |
| IL (1) | IL98090A (xx) |
| NZ (1) | NZ238092A (xx) |
| PT (1) | PT97614A (xx) |
| WO (1) | WO1991017160A1 (xx) |
| ZA (1) | ZA913546B (xx) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2677021B1 (fr) * | 1991-05-31 | 1993-10-01 | Upsa Laboratoires | Nouveaux derives de thiazole antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant. |
| US5352690A (en) * | 1992-07-01 | 1994-10-04 | Eli Lilly And Company | 1,2,4-trioxygenated benzene derivatives useful as leukotriene antagonists |
| AU2585595A (en) * | 1994-05-25 | 1995-12-18 | G.D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-sulfonimides derivatives, their preparation and their use as leukotriene b4 antagonists |
| US5516917A (en) * | 1994-06-08 | 1996-05-14 | G. D. Searle & Co. | Leukotriene B4 antagonists |
| CA2202056A1 (en) * | 1994-10-13 | 1996-04-25 | Mark A. Dombroski | Benzopyran and benzo-fused compounds, their preparation and their use as leukotriene b4' (ltb4) antagonists |
| MX9702731A (es) * | 1994-10-13 | 1997-06-28 | Pfizer | Compuestos de benzopirano y benzo fusionados, composiciones que los contienen y uso de los mismos. |
| AU1707700A (en) | 1998-10-29 | 2000-05-22 | Bristol-Myers Squibb Company | Novel inhibitors of impdh enzyme |
| EP1324995A2 (en) | 2000-09-27 | 2003-07-09 | Merck & Co., Inc. | Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders |
| EP1347755A2 (en) * | 2000-10-31 | 2003-10-01 | Merck & Co., Inc. | Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders |
| US7446127B2 (en) * | 2003-08-27 | 2008-11-04 | Sk Holdings Co, Ltd. | Chroman carboxylic acid derivatives for the treatment of diabetes and lipid disorders |
| US7709197B2 (en) | 2005-06-15 | 2010-05-04 | Callida Genomics, Inc. | Nucleic acid analysis by random mixtures of non-overlapping fragments |
| EP2546360A1 (en) | 2005-10-07 | 2013-01-16 | Callida Genomics, Inc. | Self-assembled single molecule arrays and uses thereof |
| JP5180845B2 (ja) | 2006-02-24 | 2013-04-10 | カリダ・ジェノミックス・インコーポレイテッド | Ｄｎａアレイ上でのハイスループットゲノム配列決定 |
| EP2766498B1 (en) | 2011-10-14 | 2019-06-19 | President and Fellows of Harvard College | Sequencing by structure assembly |
| WO2013184754A2 (en) | 2012-06-05 | 2013-12-12 | President And Fellows Of Harvard College | Spatial sequencing of nucleic acids using dna origami probes |
| US9476089B2 (en) | 2012-10-18 | 2016-10-25 | President And Fellows Of Harvard College | Methods of making oligonucleotide probes |
| US9540685B2 (en) | 2013-03-15 | 2017-01-10 | President And Fellows Of Harvard College | Methods of identifying homologous genes using FISH |
| WO2016028843A2 (en) | 2014-08-19 | 2016-02-25 | President And Fellows Of Harvard College | Rna-guided systems for probing and mapping of nucleic acids |
| CA3158317A1 (en) | 2019-10-18 | 2021-04-22 | The Board Of Trustees Of The Leland Stanford Junior University | Clinical- and industrial-scale intact-tissue sequencing |
| US12071667B2 (en) | 2020-11-04 | 2024-08-27 | 10X Genomics, Inc. | Sequence analysis using meta-stable nucleic acid molecules |
| US12060603B2 (en) | 2021-01-19 | 2024-08-13 | 10X Genomics, Inc. | Methods for internally controlled in situ assays using padlock probes |
| CN117396613A (zh) | 2021-06-01 | 2024-01-12 | 10X基因组学有限公司 | 用于分析物检测和探针解析的方法和组合物 |
| US20230084407A1 (en) | 2021-06-02 | 2023-03-16 | 10X Genomics, Inc. | Sample analysis using asymmetric circularizable probes |
| US20230026886A1 (en) | 2021-07-13 | 2023-01-26 | 10X Genomics, Inc. | Methods for preparing polymerized matrix with controllable thickness |
| US20230057571A1 (en) | 2021-08-03 | 2023-02-23 | 10X Genomics, Inc. | Nucleic acid concatemers and methods for stabilizing and/or compacting the same |
| EP4326898B1 (en) | 2021-08-16 | 2024-07-31 | 10X Genomics, Inc. | Probes comprising a split barcode region and methods of use |
| US20230242974A1 (en) | 2021-12-27 | 2023-08-03 | 10X Genomics, Inc. | Methods and compositions for rolling circle amplification |
| WO2023141588A1 (en) | 2022-01-21 | 2023-07-27 | 10X Genomics, Inc. | Multiple readout signals for analyzing a sample |
| US20240254537A1 (en) | 2022-02-23 | 2024-08-01 | Insitro, Inc. | Pooled optical screening and transcriptional measurements of cells comprising barcoded genetic perturbations |
| US20240026427A1 (en) | 2022-05-06 | 2024-01-25 | 10X Genomics, Inc. | Methods and compositions for in situ analysis of v(d)j sequences |
| WO2023245190A1 (en) | 2022-06-17 | 2023-12-21 | 10X Genomics, Inc. | Catalytic de-crosslinking of samples for in situ analysis |
| WO2024081869A1 (en) | 2022-10-14 | 2024-04-18 | 10X Genomics, Inc. | Methods for analysis of biological samples |
| US20240167081A1 (en) | 2022-11-08 | 2024-05-23 | 10X Genomics,Inc. | Immobilization methods and compositions for in situ detection |
| US20240158852A1 (en) | 2022-11-16 | 2024-05-16 | 10X Genomics, Inc. | Methods and compositions for assessing performance of in situ assays |
| WO2024130203A1 (en) | 2022-12-16 | 2024-06-20 | 10X Genomics, Inc. | Methods and compositions for assessing performance |
| US20240263219A1 (en) | 2023-01-06 | 2024-08-08 | 10X Genomics, Inc. | Methods and compositions for in situ analysis of variant sequences |
| US20240263220A1 (en) | 2023-02-03 | 2024-08-08 | 10X Genomics, Inc. | In situ analysis of variant sequences in biological samples |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1384530A (en) * | 1971-07-29 | 1975-02-19 | Fisons Ltd | Chromone derivatives |
| DE3070912D1 (en) * | 1979-03-20 | 1985-09-05 | Fisons Plc | Pharmaceutical heterocyclic compounds, processes for their preparation and compositions containing them |
| US4474788A (en) * | 1981-11-12 | 1984-10-02 | Fisons Plc | Anti-SRSA quinoline carboxylic acid derivatives |
| US4788214A (en) * | 1983-06-24 | 1988-11-29 | Hoffman-La Roche Inc. | 3,4-dihydro-2H-1-benzopyran derivatives |
| ZA844519B (en) * | 1983-06-24 | 1985-02-27 | Hoffmann La Roche | Dihydrobenzopyran derivatives |
| US4665203A (en) * | 1983-08-08 | 1987-05-12 | G. D. Searle & Co. | Substituted dihydrobenzopyrans useful as leukotriene D4 inhibitors |
| US4778903A (en) * | 1983-12-12 | 1988-10-18 | G. D. Searle & Co. | Substituted dihydrobenzopyrans |
| ZA84345B (en) * | 1983-08-08 | 1985-02-27 | Searle & Co | Substituted dihydrobenzopyrans |
| US4565882A (en) * | 1984-01-06 | 1986-01-21 | G. D. Searle & Co. | Substituted dihydrobenzopyran-2-carboxylates |
| US4546194A (en) * | 1984-05-29 | 1985-10-08 | G. D. Searle & Co. | Substituted chromanon-2-yl alkanols and derivatives thereof |
| US4889871A (en) * | 1987-05-29 | 1989-12-26 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives |
| MX13485A (es) * | 1987-10-19 | 1993-05-01 | Pfizer | Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos |
-
1990
- 1990-05-10 US US07/521,777 patent/US5073562A/en not_active Expired - Fee Related
-
1991
- 1991-05-01 CA CA002082500A patent/CA2082500A1/en not_active Abandoned
- 1991-05-01 DK DK91910026.3T patent/DK0527922T3/da active
- 1991-05-01 AT AT91910026T patent/ATE119528T1/de not_active IP Right Cessation
- 1991-05-01 EP EP91910026A patent/EP0527922B1/en not_active Expired - Lifetime
- 1991-05-01 JP JP91509388A patent/JPH05507084A/ja active Pending
- 1991-05-01 WO PCT/US1991/002981 patent/WO1991017160A1/en active IP Right Grant
- 1991-05-01 ES ES91910026T patent/ES2069295T3/es not_active Expired - Lifetime
- 1991-05-01 AU AU79020/91A patent/AU647487B2/en not_active Ceased
- 1991-05-01 DE DE69108025T patent/DE69108025T2/de not_active Expired - Fee Related
- 1991-05-09 IL IL9809091A patent/IL98090A/en not_active IP Right Cessation
- 1991-05-09 NZ NZ238092A patent/NZ238092A/xx unknown
- 1991-05-09 IE IE158391A patent/IE62719B1/en not_active IP Right Cessation
- 1991-05-09 PT PT97614A patent/PT97614A/pt not_active Application Discontinuation
- 1991-05-10 ZA ZA913546A patent/ZA913546B/xx unknown
-
1995
- 1995-03-09 GR GR950400438T patent/GR3015349T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE119528T1 (de) | 1995-03-15 |
| GR3015349T3 (en) | 1995-06-30 |
| AU7902091A (en) | 1991-11-27 |
| DE69108025T2 (de) | 1995-08-10 |
| EP0527922B1 (en) | 1995-03-08 |
| US5073562A (en) | 1991-12-17 |
| JPH05507084A (ja) | 1993-10-14 |
| WO1991017160A1 (en) | 1991-11-14 |
| DK0527922T3 (da) | 1995-05-22 |
| EP0527922A1 (en) | 1993-02-24 |
| AU647487B2 (en) | 1994-03-24 |
| IL98090A (en) | 1995-07-31 |
| PT97614A (pt) | 1992-01-31 |
| IE62719B1 (en) | 1995-02-22 |
| CA2082500A1 (en) | 1991-11-11 |
| NZ238092A (en) | 1993-10-26 |
| IL98090A0 (en) | 1992-06-21 |
| IE911583A1 (en) | 1991-11-20 |
| DE69108025D1 (de) | 1995-04-13 |
| ES2069295T3 (es) | 1995-05-01 |
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