NO912429D0 - Fremgangsmaate for fremstilling av aralifatiske n-substituerte aminoalkanfosfinsyrer. - Google Patents

Fremgangsmaate for fremstilling av aralifatiske n-substituerte aminoalkanfosfinsyrer.

Info

Publication number
NO912429D0
NO912429D0 NO912429A NO912429A NO912429D0 NO 912429 D0 NO912429 D0 NO 912429D0 NO 912429 A NO912429 A NO 912429A NO 912429 A NO912429 A NO 912429A NO 912429 D0 NO912429 D0 NO 912429D0
Authority
NO
Norway
Prior art keywords
hydrogen
radical
aliphatic
preparation
araliphatic
Prior art date
Application number
NO912429A
Other languages
English (en)
Other versions
NO912429L (no
NO302476B1 (no
Inventor
Christian Marescaux
Raymond Bernasconi
Markus Schmutz
Wolfgang Froestl
Stuart J Mickel
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO912429D0 publication Critical patent/NO912429D0/no
Publication of NO912429L publication Critical patent/NO912429L/no
Publication of NO302476B1 publication Critical patent/NO302476B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/36—Amides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treating Waste Gases (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Catalysts (AREA)
  • Medicinal Preparation (AREA)
NO912429A 1990-06-22 1991-06-21 Analogifremgangsmåte for fremstilling av aralifatiske N-substituerte aminoalkanfosfinsyrer NO302476B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH209290 1990-06-22
CH44091 1991-02-13
CH119991 1991-04-22

Publications (3)

Publication Number Publication Date
NO912429D0 true NO912429D0 (no) 1991-06-21
NO912429L NO912429L (no) 1991-12-23
NO302476B1 NO302476B1 (no) 1998-03-09

Family

ID=27172107

Family Applications (1)

Application Number Title Priority Date Filing Date
NO912429A NO302476B1 (no) 1990-06-22 1991-06-21 Analogifremgangsmåte for fremstilling av aralifatiske N-substituerte aminoalkanfosfinsyrer

Country Status (21)

Country Link
US (3) US5229379A (no)
EP (1) EP0463560B1 (no)
JP (1) JP3222487B2 (no)
KR (1) KR100219315B1 (no)
AT (1) ATE129500T1 (no)
AU (1) AU641772B2 (no)
CA (1) CA2045077C (no)
DE (1) DE59106756D1 (no)
DK (1) DK0463560T3 (no)
ES (1) ES2079520T3 (no)
FI (1) FI101705B1 (no)
GR (1) GR3017895T3 (no)
HR (1) HRP940512A2 (no)
HU (1) HUT59148A (no)
IE (1) IE69314B1 (no)
IL (3) IL114631A (no)
NO (1) NO302476B1 (no)
NZ (2) NZ238636A (no)
PT (1) PT98064B (no)
SI (1) SI9111099B (no)
YU (1) YU109991A (no)

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US5281747A (en) * 1989-05-13 1994-01-25 Ciba-Geigy Corporation Substituted aminoalkylphosphinic acids
EP0543780A3 (en) * 1991-11-21 1993-09-01 Ciba-Geigy Ag Novel aminoalkanephosphinic acids and their salts
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AU662404B2 (en) * 1992-05-08 1995-08-31 Novartis Ag Novel N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids
DE4407197A1 (de) * 1994-03-04 1995-09-07 Hoechst Schering Agrevo Gmbh Verfahren zur Herstellung von /L/-Homoalanin-4-yl-(methyl)phosphinsäure und deren Salze durch Racematspaltung
AU7130196A (en) * 1995-09-28 1997-04-17 Novartis Ag Novel hydroxylated and alkoxylated N- and/or P-aralkylphosphinic acid derivatives
DE19634706A1 (de) * 1996-08-28 1998-03-05 Hoechst Ag Verfahren zur Herstellung von 2-Cyanoethyl-phosphinsäureestern
WO1998058939A1 (en) 1997-06-23 1998-12-30 Polychip Pharmaceuticals Pty. Ltd. Neurologically-active compounds
JP3382159B2 (ja) * 1998-08-05 2003-03-04 株式会社東芝 情報記録媒体とその再生方法及び記録方法
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SE9904508D0 (sv) * 1999-12-09 1999-12-09 Astra Ab New compounds
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US20050163850A1 (en) * 2003-10-31 2005-07-28 Wong Patrick S. Administration of levodopa and carbidopa
GB0327186D0 (en) 2003-11-21 2003-12-24 Novartis Ag Organic compounds
WO2006050472A2 (en) * 2004-11-03 2006-05-11 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous and -phosphinic acids
US7566738B2 (en) * 2004-11-03 2009-07-28 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
US7585996B2 (en) * 2006-09-15 2009-09-08 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
ES2432386T3 (es) 2008-11-05 2013-12-03 Clariant Finance (Bvi) Limited Procedimiento para la preparación de ácidos, ésteres y sales dialquilfosfínicos mono-carboxi-funcionalizados por medio de alcoholes alílicos/acroleínas y su uso
DE102008055914A1 (de) 2008-11-05 2010-05-06 Clariant International Limited Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acroleinen und ihre Verwendung
DE102008055916A1 (de) 2008-11-05 2010-05-06 Clariant International Limited Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Allylalkoholen und ihre Verwendung
DE102008056228A1 (de) * 2008-11-06 2010-05-12 Clariant International Limited Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, deren Salze und Ester und ihre Verwendung
DE102008056234A1 (de) * 2008-11-06 2010-05-12 Clariant International Ltd. Verfahren zur Herstellung von momo-carboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylen/Nitrilen und ihre Verwendung
DE102008056339A1 (de) * 2008-11-07 2010-05-12 Clariant International Limited Verfahren zur Herstellung von mono-aminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
DE102008056341A1 (de) 2008-11-07 2010-05-12 Clariant International Limited Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung
DE102008056342A1 (de) 2008-11-07 2010-05-12 Clariant International Limited Verfahren zur Herstellung von Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung
CN102186864A (zh) 2008-11-07 2011-09-14 科莱恩金融(Bvi)有限公司 利用丙烯酸衍生物制备二烷基次膦酸、二烷基次膦酸酯和二烷基次膦酸盐的方法，以及它们的用途
CN102171226B (zh) 2008-11-11 2015-02-11 科莱恩金融(Bvi)有限公司 利用烯丙基化合物制备单烯丙基官能化的二烷基次膦酸、其盐或酯的方法以及它们的用途
DE102008060036A1 (de) 2008-12-02 2010-06-10 Clariant International Limited Verfahren zur Herstellung von mono-carboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylester einer Carbonsäure und ihre Verwendung
DE102008060035A1 (de) 2008-12-02 2010-06-10 Clariant International Limited Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylester einer Carbonsäure und ihre Verwendung
DE102008060535A1 (de) 2008-12-04 2010-06-10 Clariant International Limited Verfahren zur Herstellung von mono-carboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylether und ihre Verwendung
DE102008063627A1 (de) 2008-12-18 2010-06-24 Clariant International Limited Verfahren zur Herstellung von monohydroxyfunktionalisierten Dialkylphosphinsäuren,-estern und -salzen mittels Ethylenoxid und ihre Verwendung
DE102008063640A1 (de) * 2008-12-18 2010-06-24 Clariant International Limited Verfahren zur Herstellung von gemischtsubstituierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
DE102008063642A1 (de) 2008-12-18 2010-06-24 Clariant International Limited Verfahren zur Herstellung von monocarboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Alkylenoxiden und ihre Verwendung
DE102008063668A1 (de) 2008-12-18 2010-07-01 Clariant International Limited Verfahren zur Herstellung von Alkylphosponsäuren, -estern und -salzen mittels Oxidation von Alkylphosphonigsäuren und ihre Verwendung
WO2010069545A2 (de) 2008-12-18 2010-06-24 Clariant International Ltd Verfahren zur herstellung von ethylendialkylphosphinsäuren, -estern und -salzen mittels acetylen und ihre verwendung
DE102008064012A1 (de) 2008-12-19 2010-06-24 Clariant International Limited Halogenfreie Addukte von Alkylphosphonigsäurederivaten und diesterbildenden Olefinen, halogenfreie Verfahren zu deren Herstellung und ihre Verwendung
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Also Published As

Publication number Publication date
CA2045077A1 (en) 1991-12-23
SI9111099A (sl) 1998-02-28
JP3222487B2 (ja) 2001-10-29
YU109991A (sh) 1994-06-24
HRP940512A2 (en) 1996-04-30
EP0463560A1 (de) 1992-01-02
US5229379A (en) 1993-07-20
FI101705B (fi) 1998-08-14
PT98064B (pt) 1998-10-30
DE59106756D1 (de) 1995-11-30
IL114631A0 (en) 1995-11-27
FI912998A (fi) 1991-12-23
US5545631A (en) 1996-08-13
CA2045077C (en) 2002-08-20
HU912064D0 (en) 1991-12-30
GR3017895T3 (en) 1996-01-31
IL114631A (en) 1998-12-06
ATE129500T1 (de) 1995-11-15
IE69314B1 (en) 1996-09-04
KR100219315B1 (ko) 1999-10-01
NO912429L (no) 1991-12-23
IL98502A (en) 1998-04-05
JPH04243829A (ja) 1992-08-31
NO302476B1 (no) 1998-03-09
NZ247934A (en) 1997-07-27
EP0463560B1 (de) 1995-10-25
FI101705B1 (fi) 1998-08-14
AU7922091A (en) 1992-01-02
SI9111099B (en) 2001-06-30
FI912998A0 (fi) 1991-06-19
ES2079520T3 (es) 1996-01-16
HUT59148A (en) 1992-04-28
NZ238636A (en) 1994-12-22
DK0463560T3 (da) 1995-12-04
US5407922A (en) 1995-04-18
IL98502A0 (en) 1992-07-15
IE912158A1 (en) 1992-01-01
AU641772B2 (en) 1993-09-30
KR920000774A (ko) 1992-01-29
PT98064A (pt) 1992-04-30

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