IL98090A - Dihydrobenzofiran-2-carboxylic acids converted by alkoxy and their history and pharmaceutical preparations containing them - Google Patents
Dihydrobenzofiran-2-carboxylic acids converted by alkoxy and their history and pharmaceutical preparations containing themInfo
- Publication number
- IL98090A IL98090A IL9809091A IL9809091A IL98090A IL 98090 A IL98090 A IL 98090A IL 9809091 A IL9809091 A IL 9809091A IL 9809091 A IL9809091 A IL 9809091A IL 98090 A IL98090 A IL 98090A
- Authority
- IL
- Israel
- Prior art keywords
- propyl
- carbon atoms
- compound
- dihydro
- benzopyran
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/521,777 US5073562A (en) | 1990-05-10 | 1990-05-10 | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL98090A0 IL98090A0 (en) | 1992-06-21 |
| IL98090A true IL98090A (en) | 1995-07-31 |
Family
ID=24078110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9809091A IL98090A (en) | 1990-05-10 | 1991-05-09 | Dihydrobenzofiran-2-carboxylic acids converted by alkoxy and their history and pharmaceutical preparations containing them |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5073562A (xx) |
| EP (1) | EP0527922B1 (xx) |
| JP (1) | JPH05507084A (xx) |
| AT (1) | ATE119528T1 (xx) |
| AU (1) | AU647487B2 (xx) |
| CA (1) | CA2082500A1 (xx) |
| DE (1) | DE69108025T2 (xx) |
| DK (1) | DK0527922T3 (xx) |
| ES (1) | ES2069295T3 (xx) |
| GR (1) | GR3015349T3 (xx) |
| IE (1) | IE62719B1 (xx) |
| IL (1) | IL98090A (xx) |
| NZ (1) | NZ238092A (xx) |
| PT (1) | PT97614A (xx) |
| WO (1) | WO1991017160A1 (xx) |
| ZA (1) | ZA913546B (xx) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2677021B1 (fr) * | 1991-05-31 | 1993-10-01 | Upsa Laboratoires | Nouveaux derives de thiazole antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant. |
| US5352690A (en) * | 1992-07-01 | 1994-10-04 | Eli Lilly And Company | 1,2,4-trioxygenated benzene derivatives useful as leukotriene antagonists |
| WO1995032201A1 (en) * | 1994-05-25 | 1995-11-30 | G.D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-sulfonimides derivatives, their preparation and their use as leukotriene b4 antagonists |
| US5516917A (en) * | 1994-06-08 | 1996-05-14 | G. D. Searle & Co. | Leukotriene B4 antagonists |
| KR100232340B1 (ko) * | 1994-10-13 | 1999-12-01 | 디. 제이. 우드, 스피겔 알렌 제이 | 류코트리엔 b4(ltb4) 길항물질로서의 벤조피란 및 벤조-축합된 화합물 |
| MX9702731A (es) * | 1994-10-13 | 1997-06-28 | Pfizer | Compuestos de benzopirano y benzo fusionados, composiciones que los contienen y uso de los mismos. |
| WO2000026197A1 (en) * | 1998-10-29 | 2000-05-11 | Bristol-Myers Squibb Company | Novel inhibitors of impdh enzyme |
| JP2004513090A (ja) | 2000-09-27 | 2004-04-30 | メルク エンド カムパニー インコーポレーテッド | 糖尿病及び脂質異常症の治療のためのベンゾピランカルボン酸誘導体 |
| EP1347755A2 (en) * | 2000-10-31 | 2003-10-01 | Merck & Co., Inc. | Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders |
| US7446127B2 (en) * | 2003-08-27 | 2008-11-04 | Sk Holdings Co, Ltd. | Chroman carboxylic acid derivatives for the treatment of diabetes and lipid disorders |
| CA2611671C (en) | 2005-06-15 | 2013-10-08 | Callida Genomics, Inc. | Single molecule arrays for genetic and chemical analysis |
| EP1951900B1 (en) | 2005-10-07 | 2016-06-15 | Callida Genomics, Inc. | Self-assembled single molecule arrays and uses thereof |
| EP1994180A4 (en) | 2006-02-24 | 2009-11-25 | Callida Genomics Inc | GENOME SEQUENCING ON DNA ARRAYS WITH HIGH THROUGHPUT |
| EP3604555A1 (en) | 2011-10-14 | 2020-02-05 | President and Fellows of Harvard College | Sequencing by structure assembly |
| US9914967B2 (en) | 2012-06-05 | 2018-03-13 | President And Fellows Of Harvard College | Spatial sequencing of nucleic acids using DNA origami probes |
| US9476089B2 (en) | 2012-10-18 | 2016-10-25 | President And Fellows Of Harvard College | Methods of making oligonucleotide probes |
| US9540685B2 (en) | 2013-03-15 | 2017-01-10 | President And Fellows Of Harvard College | Methods of identifying homologous genes using FISH |
| EP3183358B1 (en) | 2014-08-19 | 2020-10-07 | President and Fellows of Harvard College | Rna-guided systems for probing and mapping of nucleic acids |
| EP4045887A4 (en) | 2019-10-18 | 2023-11-15 | The Board of Trustees of the Leland Stanford Junior University | SEQUENCING OF INTACT TISSUE AT CLINICAL AND INDUSTRIAL LEVELS |
| US12071667B2 (en) | 2020-11-04 | 2024-08-27 | 10X Genomics, Inc. | Sequence analysis using meta-stable nucleic acid molecules |
| US12060603B2 (en) | 2021-01-19 | 2024-08-13 | 10X Genomics, Inc. | Methods for internally controlled in situ assays using padlock probes |
| WO2022256324A1 (en) | 2021-06-01 | 2022-12-08 | 10X Genomics, Inc. | Methods and compositions for analyte detection and probe resolution |
| EP4347880A1 (en) | 2021-06-02 | 2024-04-10 | 10X Genomics, Inc. | Sample analysis using asymmetric circularizable probes |
| US20230026886A1 (en) | 2021-07-13 | 2023-01-26 | 10X Genomics, Inc. | Methods for preparing polymerized matrix with controllable thickness |
| CA3224093A1 (en) | 2021-07-30 | 2023-02-02 | Jorge Ivan Hernandez Neuta | Methods and compositions for synchronizing reactions in situ |
| US20230057571A1 (en) | 2021-08-03 | 2023-02-23 | 10X Genomics, Inc. | Nucleic acid concatemers and methods for stabilizing and/or compacting the same |
| US20230061542A1 (en) | 2021-08-16 | 2023-03-02 | 10X Genomics, Inc. | Probes comprising a split barcode region and methods of use |
| EP4423296A2 (en) | 2021-12-27 | 2024-09-04 | 10X Genomics, Inc. | Methods and compositions for rolling circle amplification |
| US20230279475A1 (en) | 2022-01-21 | 2023-09-07 | 10X Genomics, Inc. | Multiple readout signals for analyzing a sample |
| WO2023164570A1 (en) | 2022-02-23 | 2023-08-31 | Insitro, Inc. | Pooled optical screening and transcriptional measurements of cells comprising barcoded genetic perturbations |
| US20240026427A1 (en) | 2022-05-06 | 2024-01-25 | 10X Genomics, Inc. | Methods and compositions for in situ analysis of v(d)j sequences |
| US20240035071A1 (en) | 2022-06-17 | 2024-02-01 | 10X Genomics, Inc. | Catalytic de-crosslinking of samples for in situ analysis |
| WO2024081869A1 (en) | 2022-10-14 | 2024-04-18 | 10X Genomics, Inc. | Methods for analysis of biological samples |
| US20240167081A1 (en) | 2022-11-08 | 2024-05-23 | 10X Genomics,Inc. | Immobilization methods and compositions for in situ detection |
| US20240158852A1 (en) | 2022-11-16 | 2024-05-16 | 10X Genomics, Inc. | Methods and compositions for assessing performance of in situ assays |
| US20240218437A1 (en) | 2022-12-16 | 2024-07-04 | 10X Genomics, Inc. | Methods and compositions for assessing performance |
| US20240263219A1 (en) | 2023-01-06 | 2024-08-08 | 10X Genomics, Inc. | Methods and compositions for in situ analysis of variant sequences |
| US20240263220A1 (en) | 2023-02-03 | 2024-08-08 | 10X Genomics, Inc. | In situ analysis of variant sequences in biological samples |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1384530A (en) * | 1971-07-29 | 1975-02-19 | Fisons Ltd | Chromone derivatives |
| ATE14579T1 (de) * | 1979-03-20 | 1985-08-15 | Fisons Plc | Pharmazeutische heterocyclische verbindungen, verfahren zu ihrer herstellung und sie enthaltende zusammensetzungen. |
| US4474788A (en) * | 1981-11-12 | 1984-10-02 | Fisons Plc | Anti-SRSA quinoline carboxylic acid derivatives |
| ZA844519B (en) * | 1983-06-24 | 1985-02-27 | Hoffmann La Roche | Dihydrobenzopyran derivatives |
| US4788214A (en) * | 1983-06-24 | 1988-11-29 | Hoffman-La Roche Inc. | 3,4-dihydro-2H-1-benzopyran derivatives |
| ZA84345B (en) * | 1983-08-08 | 1985-02-27 | Searle & Co | Substituted dihydrobenzopyrans |
| US4778903A (en) * | 1983-12-12 | 1988-10-18 | G. D. Searle & Co. | Substituted dihydrobenzopyrans |
| US4665203A (en) * | 1983-08-08 | 1987-05-12 | G. D. Searle & Co. | Substituted dihydrobenzopyrans useful as leukotriene D4 inhibitors |
| US4565882A (en) * | 1984-01-06 | 1986-01-21 | G. D. Searle & Co. | Substituted dihydrobenzopyran-2-carboxylates |
| US4546194A (en) * | 1984-05-29 | 1985-10-08 | G. D. Searle & Co. | Substituted chromanon-2-yl alkanols and derivatives thereof |
| US4889871A (en) * | 1987-05-29 | 1989-12-26 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives |
| MX13485A (es) * | 1987-10-19 | 1993-05-01 | Pfizer | Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos |
-
1990
- 1990-05-10 US US07/521,777 patent/US5073562A/en not_active Expired - Fee Related
-
1991
- 1991-05-01 JP JP91509388A patent/JPH05507084A/ja active Pending
- 1991-05-01 AT AT91910026T patent/ATE119528T1/de not_active IP Right Cessation
- 1991-05-01 EP EP91910026A patent/EP0527922B1/en not_active Expired - Lifetime
- 1991-05-01 DK DK91910026.3T patent/DK0527922T3/da active
- 1991-05-01 WO PCT/US1991/002981 patent/WO1991017160A1/en active IP Right Grant
- 1991-05-01 AU AU79020/91A patent/AU647487B2/en not_active Ceased
- 1991-05-01 DE DE69108025T patent/DE69108025T2/de not_active Expired - Fee Related
- 1991-05-01 ES ES91910026T patent/ES2069295T3/es not_active Expired - Lifetime
- 1991-05-01 CA CA002082500A patent/CA2082500A1/en not_active Abandoned
- 1991-05-09 NZ NZ238092A patent/NZ238092A/xx unknown
- 1991-05-09 IL IL9809091A patent/IL98090A/en not_active IP Right Cessation
- 1991-05-09 IE IE158391A patent/IE62719B1/en not_active IP Right Cessation
- 1991-05-09 PT PT97614A patent/PT97614A/pt not_active Application Discontinuation
- 1991-05-10 ZA ZA913546A patent/ZA913546B/xx unknown
-
1995
- 1995-03-09 GR GR950400438T patent/GR3015349T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2082500A1 (en) | 1991-11-11 |
| DE69108025D1 (de) | 1995-04-13 |
| GR3015349T3 (en) | 1995-06-30 |
| IL98090A0 (en) | 1992-06-21 |
| IE62719B1 (en) | 1995-02-22 |
| WO1991017160A1 (en) | 1991-11-14 |
| NZ238092A (en) | 1993-10-26 |
| EP0527922A1 (en) | 1993-02-24 |
| JPH05507084A (ja) | 1993-10-14 |
| EP0527922B1 (en) | 1995-03-08 |
| US5073562A (en) | 1991-12-17 |
| ZA913546B (en) | 1992-07-29 |
| AU7902091A (en) | 1991-11-27 |
| DK0527922T3 (da) | 1995-05-22 |
| ES2069295T3 (es) | 1995-05-01 |
| AU647487B2 (en) | 1994-03-24 |
| PT97614A (pt) | 1992-01-31 |
| ATE119528T1 (de) | 1995-03-15 |
| DE69108025T2 (de) | 1995-08-10 |
| IE911583A1 (en) | 1991-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |