ZA903804B - A method of potentiating cell-mediated immunity utilizing polyamine derivatives - Google Patents

A method of potentiating cell-mediated immunity utilizing polyamine derivatives

Info

Publication number
ZA903804B
ZA903804B ZA903804A ZA903804A ZA903804B ZA 903804 B ZA903804 B ZA 903804B ZA 903804 A ZA903804 A ZA 903804A ZA 903804 A ZA903804 A ZA 903804A ZA 903804 B ZA903804 B ZA 903804B
Authority
ZA
South Africa
Prior art keywords
mediated immunity
polyamine derivatives
potentiating cell
potentiating
cell
Prior art date
Application number
ZA903804A
Other languages
English (en)
Inventor
Terry Lynn Bowlin
Lynn Bowlin Terry
Nellikunja Jaya Prakash
Jaya Prakash Nellikunja
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA903804B publication Critical patent/ZA903804B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
ZA903804A 1989-05-23 1990-05-17 A method of potentiating cell-mediated immunity utilizing polyamine derivatives ZA903804B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35573689A 1989-05-23 1989-05-23

Publications (1)

Publication Number Publication Date
ZA903804B true ZA903804B (en) 1991-03-27

Family

ID=23398633

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA903804A ZA903804B (en) 1989-05-23 1990-05-17 A method of potentiating cell-mediated immunity utilizing polyamine derivatives

Country Status (11)

Country Link
EP (1) EP0399519B1 (fr)
JP (1) JP2835773B2 (fr)
KR (1) KR900017577A (fr)
AT (1) ATE141048T1 (fr)
AU (1) AU628174B2 (fr)
DE (1) DE69028006T2 (fr)
DK (1) DK0399519T3 (fr)
ES (1) ES2092481T3 (fr)
GR (1) GR3021500T3 (fr)
IE (1) IE81081B1 (fr)
ZA (1) ZA903804B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU648846B2 (en) * 1990-12-13 1994-05-05 Merrell Dow Pharmaceuticals Inc. Method of treating cancer by conjunctive therapy with N,N-bis(3-(ethylamino)propyl)-1,7-heptanediamine and a cytotoxic agent
US5561136A (en) * 1990-12-13 1996-10-01 Merrell Pharmaceuticals Inc. Method of treating cancer by conjunctive therapy with N,N'-bis[ethylamino)propyl]-1,7-heptanediamine and a cytotoxic agent
GB9220921D0 (en) * 1992-10-05 1992-11-18 Merrell Dow Pharma Polyamine derivatives as anticytomegaloviral agents
SG49032A1 (en) * 1993-11-15 1998-05-18 Baker Med Res Inst A method for treating cardiac dysfunction and pharmaceutical compositions useful therefor
FR2724379B1 (fr) * 1994-09-13 1996-11-29 Fournier Sca Lab Procede de fabrication de polyamines qui sont des homologues structuraux de la spermidine.
US5516807A (en) * 1994-10-25 1996-05-14 Warner-Lambert Company Method for treating vascular proliferative disorders following balloon angioplasty
US8198334B2 (en) 1997-10-27 2012-06-12 Pathologica Llc Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
US7087648B1 (en) 1997-10-27 2006-08-08 The Regents Of The University Of California Methods for modulating macrophage proliferation using polyamine analogs
AU2003231670B2 (en) * 1997-10-27 2006-06-08 Slil Biomedical Corporation Methods for modulating macrophage proliferation using polyamine analogs
AU5173501A (en) * 2000-03-24 2001-10-08 Oridigm Corp Polyamine analogues as cytotoxic agents
US6919483B2 (en) * 2003-05-23 2005-07-19 Mediquest Therapeutics, Inc. Immunomodulation with novel pharmaceutical compositions
CN111989316B (zh) * 2018-01-30 2023-09-08 潘贝拉治疗股份有限公司 用于生产(6s,15s)-3,8,13,18-四氮杂二十烷-6,15-二醇的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5998015A (ja) * 1982-11-27 1984-06-06 Microbial Chem Res Found 免疫賦活剤
NZ212053A (en) * 1984-05-17 1988-02-29 Merrell Dow Pharma Polyamine containing pharmaceutical compositions for treating neoplasms
JPS62263127A (ja) * 1986-05-06 1987-11-16 メレルダウフア−マス−テイカルズ インコ−ポレ−テツド 自己由来のlak細胞、インタ−ロイキン−2、及びオルニチンデカルボキシラ−ゼ阻害剤による腫瘍の処置
CA1338764C (fr) * 1987-02-03 1996-12-03 David M. Stemerick Derives de polyamine

Also Published As

Publication number Publication date
DE69028006T2 (de) 1997-03-20
IE81081B1 (en) 2000-02-23
DK0399519T3 (da) 1996-09-02
IE901845L (en) 1990-11-23
ATE141048T1 (de) 1996-08-15
KR900017577A (ko) 1990-12-19
DE69028006D1 (de) 1996-09-12
JP2835773B2 (ja) 1998-12-14
EP0399519A3 (fr) 1991-12-04
EP0399519A2 (fr) 1990-11-28
AU628174B2 (en) 1992-09-10
AU5517190A (en) 1990-11-29
EP0399519B1 (fr) 1996-08-07
ES2092481T3 (es) 1996-12-01
GR3021500T3 (en) 1997-01-31
JPH035420A (ja) 1991-01-11

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