ZA903804B - A method of potentiating cell-mediated immunity utilizing polyamine derivatives - Google Patents

A method of potentiating cell-mediated immunity utilizing polyamine derivatives

Info

Publication number
ZA903804B
ZA903804B ZA903804A ZA903804A ZA903804B ZA 903804 B ZA903804 B ZA 903804B ZA 903804 A ZA903804 A ZA 903804A ZA 903804 A ZA903804 A ZA 903804A ZA 903804 B ZA903804 B ZA 903804B
Authority
ZA
South Africa
Prior art keywords
mediated immunity
polyamine derivatives
potentiating cell
potentiating
cell
Prior art date
Application number
ZA903804A
Other languages
English (en)
Inventor
Terry Lynn Bowlin
Lynn Bowlin Terry
Nellikunja Jaya Prakash
Jaya Prakash Nellikunja
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA903804B publication Critical patent/ZA903804B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA903804A 1989-05-23 1990-05-17 A method of potentiating cell-mediated immunity utilizing polyamine derivatives ZA903804B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35573689A 1989-05-23 1989-05-23

Publications (1)

Publication Number Publication Date
ZA903804B true ZA903804B (en) 1991-03-27

Family

ID=23398633

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA903804A ZA903804B (en) 1989-05-23 1990-05-17 A method of potentiating cell-mediated immunity utilizing polyamine derivatives

Country Status (11)

Country Link
EP (1) EP0399519B1 (xx)
JP (1) JP2835773B2 (xx)
KR (1) KR900017577A (xx)
AT (1) ATE141048T1 (xx)
AU (1) AU628174B2 (xx)
DE (1) DE69028006T2 (xx)
DK (1) DK0399519T3 (xx)
ES (1) ES2092481T3 (xx)
GR (1) GR3021500T3 (xx)
IE (1) IE81081B1 (xx)
ZA (1) ZA903804B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5561136A (en) * 1990-12-13 1996-10-01 Merrell Pharmaceuticals Inc. Method of treating cancer by conjunctive therapy with N,N'-bis[ethylamino)propyl]-1,7-heptanediamine and a cytotoxic agent
ZA919695B (en) * 1990-12-13 1992-09-30 Merrell Dow Pharma Method of treating cancer by conjunctive therapy with n,n'-bis(3-(ethylamino)propyl)-1,7-heptanediamine and a cytotoxic agent
GB9220921D0 (en) * 1992-10-05 1992-11-18 Merrell Dow Pharma Polyamine derivatives as anticytomegaloviral agents
JPH09505058A (ja) * 1993-11-15 1997-05-20 ベイカー・メディカル・リサーチ・インスティテュート 心機能不全の治療方法およびそのために有用な医薬組成物
FR2724379B1 (fr) * 1994-09-13 1996-11-29 Fournier Sca Lab Procede de fabrication de polyamines qui sont des homologues structuraux de la spermidine.
US5516807A (en) * 1994-10-25 1996-05-14 Warner-Lambert Company Method for treating vascular proliferative disorders following balloon angioplasty
US7087648B1 (en) 1997-10-27 2006-08-08 The Regents Of The University Of California Methods for modulating macrophage proliferation using polyamine analogs
US8198334B2 (en) 1997-10-27 2012-06-12 Pathologica Llc Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
AU2003231670B2 (en) * 1997-10-27 2006-06-08 Slil Biomedical Corporation Methods for modulating macrophage proliferation using polyamine analogs
AU2001251735B2 (en) * 2000-03-24 2005-09-01 Mediquest Therapeutics, Inc. Polyamine analogues as cytotoxic agents
US6919483B2 (en) * 2003-05-23 2005-07-19 Mediquest Therapeutics, Inc. Immunomodulation with novel pharmaceutical compositions
CA3089388A1 (en) * 2018-01-30 2019-08-08 Sun Biopharma, Inc. Methods for producing (6s,15s)-3,8,13,18-tetraazaicosane-6,15-diol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5998015A (ja) * 1982-11-27 1984-06-06 Microbial Chem Res Found 免疫賦活剤
NZ212053A (en) * 1984-05-17 1988-02-29 Merrell Dow Pharma Polyamine containing pharmaceutical compositions for treating neoplasms
JPS62263127A (ja) * 1986-05-06 1987-11-16 メレルダウフア−マス−テイカルズ インコ−ポレ−テツド 自己由来のlak細胞、インタ−ロイキン−2、及びオルニチンデカルボキシラ−ゼ阻害剤による腫瘍の処置
NZ223340A (en) * 1987-02-03 1991-03-26 Merrell Dow Pharma Polyamine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
DK0399519T3 (da) 1996-09-02
EP0399519A3 (en) 1991-12-04
GR3021500T3 (en) 1997-01-31
JP2835773B2 (ja) 1998-12-14
EP0399519A2 (en) 1990-11-28
DE69028006T2 (de) 1997-03-20
DE69028006D1 (de) 1996-09-12
AU5517190A (en) 1990-11-29
JPH035420A (ja) 1991-01-11
ATE141048T1 (de) 1996-08-15
AU628174B2 (en) 1992-09-10
ES2092481T3 (es) 1996-12-01
KR900017577A (ko) 1990-12-19
EP0399519B1 (en) 1996-08-07
IE901845L (en) 1990-11-23
IE81081B1 (en) 2000-02-23

Similar Documents

Publication Publication Date Title
TW349946B (en) Novel naphthyl compounds and their process for preparation and pharmaceutical compositions containing same
ZA903804B (en) A method of potentiating cell-mediated immunity utilizing polyamine derivatives
HUT61300A (en) Process for producing pyrazolepyridine derivatives and pharmaceutical compositions comprising same as active ingredient
NZ229347A (en) Substituted cephalosporin derivatives; pharmaceutical compositions, preparatory processes and intermediates
MY106314A (en) New tetrazole derivatives, process for their preparation and their use
AU2347088A (en) Polyamine derivatives as antineoplastic agents
IL85822A (en) 7-alkanesulphonoamido-1,2,4,5-tetrahydro-3h-3-benzazepine derivatives,their preparation and pharmaceutical compositions containing them
HUT53522A (en) Process for producing pharmaceutical compositions comprising purine derivatives
ES556551A0 (es) Un procedimiento para preparar un derivado de 1,5-benzotiazepina
AU657423B2 (en) Novel piperidine derivatives and process for preparation thereof
MY109729A (en) Benzofuranylimidazole derivatives, a process for the preparation and therapeutical compositions containing the same
GR81759B (xx)
GB2190587B (en) Prophylactic and curing composition for arteriosclerosis
EP0322248A3 (en) Compounds effective against cerebral insufficiency
PT99964A (pt) Derivados de partricina processo para a sua preparacao e composicoes farmaceuticas que os contem
IL116557A0 (en) Antiherpes peptidomimetic compounds their preparation and pharmaceutical compositions containing them