DE69028006D1 - Verwendung von Polyaminderivaten zur Verstärkung der zellularen Immunität - Google Patents

Verwendung von Polyaminderivaten zur Verstärkung der zellularen Immunität

Info

Publication number
DE69028006D1
DE69028006D1 DE69028006T DE69028006T DE69028006D1 DE 69028006 D1 DE69028006 D1 DE 69028006D1 DE 69028006 T DE69028006 T DE 69028006T DE 69028006 T DE69028006 T DE 69028006T DE 69028006 D1 DE69028006 D1 DE 69028006D1
Authority
DE
Germany
Prior art keywords
cellular immunity
enhance cellular
polyamine derivatives
saturated
integer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69028006T
Other languages
English (en)
Other versions
DE69028006T2 (de
Inventor
Terry L Bowlin
Nellikunja Prakash
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69028006D1 publication Critical patent/DE69028006D1/de
Publication of DE69028006T2 publication Critical patent/DE69028006T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE69028006T 1989-05-23 1990-05-23 Verwendung von Polyaminderivaten zur Verstärkung der zellularen Immunität Expired - Fee Related DE69028006T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35573689A 1989-05-23 1989-05-23

Publications (2)

Publication Number Publication Date
DE69028006D1 true DE69028006D1 (de) 1996-09-12
DE69028006T2 DE69028006T2 (de) 1997-03-20

Family

ID=23398633

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69028006T Expired - Fee Related DE69028006T2 (de) 1989-05-23 1990-05-23 Verwendung von Polyaminderivaten zur Verstärkung der zellularen Immunität

Country Status (11)

Country Link
EP (1) EP0399519B1 (de)
JP (1) JP2835773B2 (de)
KR (1) KR900017577A (de)
AT (1) ATE141048T1 (de)
AU (1) AU628174B2 (de)
DE (1) DE69028006T2 (de)
DK (1) DK0399519T3 (de)
ES (1) ES2092481T3 (de)
GR (1) GR3021500T3 (de)
IE (1) IE81081B1 (de)
ZA (1) ZA903804B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU648846B2 (en) * 1990-12-13 1994-05-05 Merrell Dow Pharmaceuticals Inc. Method of treating cancer by conjunctive therapy with N,N-bis(3-(ethylamino)propyl)-1,7-heptanediamine and a cytotoxic agent
US5561136A (en) * 1990-12-13 1996-10-01 Merrell Pharmaceuticals Inc. Method of treating cancer by conjunctive therapy with N,N'-bis[ethylamino)propyl]-1,7-heptanediamine and a cytotoxic agent
GB9220921D0 (en) * 1992-10-05 1992-11-18 Merrell Dow Pharma Polyamine derivatives as anticytomegaloviral agents
JPH09505058A (ja) * 1993-11-15 1997-05-20 ベイカー・メディカル・リサーチ・インスティテュート 心機能不全の治療方法およびそのために有用な医薬組成物
FR2724379B1 (fr) * 1994-09-13 1996-11-29 Fournier Sca Lab Procede de fabrication de polyamines qui sont des homologues structuraux de la spermidine.
US5516807A (en) * 1994-10-25 1996-05-14 Warner-Lambert Company Method for treating vascular proliferative disorders following balloon angioplasty
US8198334B2 (en) 1997-10-27 2012-06-12 Pathologica Llc Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
AU2003231670B2 (en) * 1997-10-27 2006-06-08 Slil Biomedical Corporation Methods for modulating macrophage proliferation using polyamine analogs
US7087648B1 (en) 1997-10-27 2006-08-08 The Regents Of The University Of California Methods for modulating macrophage proliferation using polyamine analogs
JP2004500406A (ja) 2000-03-24 2004-01-08 メディクエスト　セラピューティックス　インク 細胞毒性剤としてのポリアミン類似体
US6919483B2 (en) * 2003-05-23 2005-07-19 Mediquest Therapeutics, Inc. Immunomodulation with novel pharmaceutical compositions
WO2019152373A1 (en) * 2018-01-30 2019-08-08 Sun Biopharma, Inc. Methods for producing (6s,15s)-3,8,13,18-tetraazaicosane-6,15-diol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5998015A (ja) * 1982-11-27 1984-06-06 Microbial Chem Res Found 免疫賦活剤
NZ212053A (en) * 1984-05-17 1988-02-29 Merrell Dow Pharma Polyamine containing pharmaceutical compositions for treating neoplasms
JPS62263127A (ja) * 1986-05-06 1987-11-16 メレルダウフア−マス−テイカルズ　インコ−ポレ−テツド 自己由来のｌａｋ細胞、インタ−ロイキン−２、及びオルニチンデカルボキシラ−ゼ阻害剤による腫瘍の処置
AU602186B2 (en) * 1987-02-03 1990-10-04 Merrell Dow Pharmaceuticals Inc. Novel polyamine derivatives

Also Published As

Publication number Publication date
AU5517190A (en) 1990-11-29
DE69028006T2 (de) 1997-03-20
DK0399519T3 (da) 1996-09-02
KR900017577A (ko) 1990-12-19
JP2835773B2 (ja) 1998-12-14
ES2092481T3 (es) 1996-12-01
IE81081B1 (en) 2000-02-23
EP0399519B1 (de) 1996-08-07
ZA903804B (en) 1991-03-27
JPH035420A (ja) 1991-01-11
ATE141048T1 (de) 1996-08-15
GR3021500T3 (en) 1997-01-31
AU628174B2 (en) 1992-09-10
IE901845L (en) 1990-11-23
EP0399519A3 (de) 1991-12-04
EP0399519A2 (de) 1990-11-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee