ES2092481T3 - Uso de derivados de poliamina para la potencializacion de la inmunidad celular. - Google Patents
Uso de derivados de poliamina para la potencializacion de la inmunidad celular.Info
- Publication number
- ES2092481T3 ES2092481T3 ES90109847T ES90109847T ES2092481T3 ES 2092481 T3 ES2092481 T3 ES 2092481T3 ES 90109847 T ES90109847 T ES 90109847T ES 90109847 T ES90109847 T ES 90109847T ES 2092481 T3 ES2092481 T3 ES 2092481T3
- Authority
- ES
- Spain
- Prior art keywords
- potentialization
- cellular immunity
- polyamine derivatives
- saturated
- integer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
EL INVENTO SE REFIRE AL USO DE UN COMPUESTO DE LA FORMULA: RHN-Z-NH- (CH2)M-NH-Z-NHR O LAS SALES FARMACEUTICAMENTE ACEPTABLES DEL MISMO EN DONDE M ES UN ENTERO ENTRE 3 Y 12, Z ES UNA MOLECULA DE ALQUILENO C2-C6 SATURADA, DE CONFIGURACION DE CADENA RECTA O RAMIFICADA, CADA GRUPO R ES INDEPENDIENTEMENTE H, UN HIDROCARBIL C1-C6 SATURADO O INSATURADO, O BIEN -(CH2)X-(AR)-X EN DONDE X ES H, ALCOXIDO C1-C6, HALOGENO, ALQUIL C1-C4, O -S(0)XR1, X ES UN ENTERO ENTRE 0,1 O 2, Y R1 ES ALQUIL C1-C6. EL COMPUESTO ES UTIL PARA LA POTENCIACION DE LA INMUNIDAD CELULAR.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35573689A | 1989-05-23 | 1989-05-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2092481T3 true ES2092481T3 (es) | 1996-12-01 |
Family
ID=23398633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90109847T Expired - Lifetime ES2092481T3 (es) | 1989-05-23 | 1990-05-23 | Uso de derivados de poliamina para la potencializacion de la inmunidad celular. |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0399519B1 (es) |
JP (1) | JP2835773B2 (es) |
KR (1) | KR900017577A (es) |
AT (1) | ATE141048T1 (es) |
AU (1) | AU628174B2 (es) |
DE (1) | DE69028006T2 (es) |
DK (1) | DK0399519T3 (es) |
ES (1) | ES2092481T3 (es) |
GR (1) | GR3021500T3 (es) |
IE (1) | IE81081B1 (es) |
ZA (1) | ZA903804B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5561136A (en) * | 1990-12-13 | 1996-10-01 | Merrell Pharmaceuticals Inc. | Method of treating cancer by conjunctive therapy with N,N'-bis[ethylamino)propyl]-1,7-heptanediamine and a cytotoxic agent |
ZA919695B (en) * | 1990-12-13 | 1992-09-30 | Merrell Dow Pharma | Method of treating cancer by conjunctive therapy with n,n'-bis(3-(ethylamino)propyl)-1,7-heptanediamine and a cytotoxic agent |
GB9220921D0 (en) * | 1992-10-05 | 1992-11-18 | Merrell Dow Pharma | Polyamine derivatives as anticytomegaloviral agents |
JPH09505058A (ja) * | 1993-11-15 | 1997-05-20 | ベイカー・メディカル・リサーチ・インスティテュート | 心機能不全の治療方法およびそのために有用な医薬組成物 |
FR2724379B1 (fr) * | 1994-09-13 | 1996-11-29 | Fournier Sca Lab | Procede de fabrication de polyamines qui sont des homologues structuraux de la spermidine. |
US5516807A (en) * | 1994-10-25 | 1996-05-14 | Warner-Lambert Company | Method for treating vascular proliferative disorders following balloon angioplasty |
US7087648B1 (en) | 1997-10-27 | 2006-08-08 | The Regents Of The University Of California | Methods for modulating macrophage proliferation using polyamine analogs |
US8198334B2 (en) | 1997-10-27 | 2012-06-12 | Pathologica Llc | Methods for modulating macrophage proliferation in ocular disease using polyamine analogs |
AU2003231670B2 (en) * | 1997-10-27 | 2006-06-08 | Slil Biomedical Corporation | Methods for modulating macrophage proliferation using polyamine analogs |
AU2001251735B2 (en) * | 2000-03-24 | 2005-09-01 | Mediquest Therapeutics, Inc. | Polyamine analogues as cytotoxic agents |
US6919483B2 (en) * | 2003-05-23 | 2005-07-19 | Mediquest Therapeutics, Inc. | Immunomodulation with novel pharmaceutical compositions |
CA3089388A1 (en) * | 2018-01-30 | 2019-08-08 | Sun Biopharma, Inc. | Methods for producing (6s,15s)-3,8,13,18-tetraazaicosane-6,15-diol |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5998015A (ja) * | 1982-11-27 | 1984-06-06 | Microbial Chem Res Found | 免疫賦活剤 |
NZ212053A (en) * | 1984-05-17 | 1988-02-29 | Merrell Dow Pharma | Polyamine containing pharmaceutical compositions for treating neoplasms |
JPS62263127A (ja) * | 1986-05-06 | 1987-11-16 | メレルダウフア−マス−テイカルズ インコ−ポレ−テツド | 自己由来のlak細胞、インタ−ロイキン−2、及びオルニチンデカルボキシラ−ゼ阻害剤による腫瘍の処置 |
NZ223340A (en) * | 1987-02-03 | 1991-03-26 | Merrell Dow Pharma | Polyamine derivatives and pharmaceutical compositions |
-
1990
- 1990-05-17 ZA ZA903804A patent/ZA903804B/xx unknown
- 1990-05-17 AU AU55171/90A patent/AU628174B2/en not_active Ceased
- 1990-05-22 IE IE184590A patent/IE81081B1/en not_active IP Right Cessation
- 1990-05-23 KR KR1019900007406A patent/KR900017577A/ko not_active Application Discontinuation
- 1990-05-23 DE DE69028006T patent/DE69028006T2/de not_active Expired - Fee Related
- 1990-05-23 JP JP2131454A patent/JP2835773B2/ja not_active Expired - Lifetime
- 1990-05-23 DK DK90109847.5T patent/DK0399519T3/da active
- 1990-05-23 AT AT90109847T patent/ATE141048T1/de not_active IP Right Cessation
- 1990-05-23 EP EP90109847A patent/EP0399519B1/en not_active Expired - Lifetime
- 1990-05-23 ES ES90109847T patent/ES2092481T3/es not_active Expired - Lifetime
-
1996
- 1996-10-30 GR GR960402869T patent/GR3021500T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DK0399519T3 (da) | 1996-09-02 |
EP0399519A3 (en) | 1991-12-04 |
GR3021500T3 (en) | 1997-01-31 |
JP2835773B2 (ja) | 1998-12-14 |
EP0399519A2 (en) | 1990-11-28 |
DE69028006T2 (de) | 1997-03-20 |
DE69028006D1 (de) | 1996-09-12 |
AU5517190A (en) | 1990-11-29 |
JPH035420A (ja) | 1991-01-11 |
ATE141048T1 (de) | 1996-08-15 |
AU628174B2 (en) | 1992-09-10 |
KR900017577A (ko) | 1990-12-19 |
EP0399519B1 (en) | 1996-08-07 |
IE901845L (en) | 1990-11-23 |
IE81081B1 (en) | 2000-02-23 |
ZA903804B (en) | 1991-03-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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