ZA902627B - Substituted 1,8-naphthyridines - Google Patents

Substituted 1,8-naphthyridines

Info

Publication number
ZA902627B
ZA902627B ZA902627A ZA902627A ZA902627B ZA 902627 B ZA902627 B ZA 902627B ZA 902627 A ZA902627 A ZA 902627A ZA 902627 A ZA902627 A ZA 902627A ZA 902627 B ZA902627 B ZA 902627B
Authority
ZA
South Africa
Prior art keywords
naphthyridines
substituted
appropriate
cyclisation
medicaments
Prior art date
Application number
ZA902627A
Other languages
English (en)
Inventor
Walter Huebsch
Huebsch Walter
Rolf Angerbauer
Angerbauer Rolf
Peter Fey
Fey Peter
Thomas Philipps
Philipps Thomas
Hilmar Bischoff
Bischoff Hilmar
Dieter Petzinna
Petzinna Dieter
Delf Schmidt
Schmidt Delf
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA902627B publication Critical patent/ZA902627B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA902627A 1989-04-06 1990-04-05 Substituted 1,8-naphthyridines ZA902627B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3911064A DE3911064A1 (de) 1989-04-06 1989-04-06 Substituierte 1,8-naphthyridine

Publications (1)

Publication Number Publication Date
ZA902627B true ZA902627B (en) 1991-01-30

Family

ID=6377950

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA902627A ZA902627B (en) 1989-04-06 1990-04-05 Substituted 1,8-naphthyridines

Country Status (14)

Country Link
US (1) US5034399A (pt)
EP (1) EP0391185B1 (pt)
JP (1) JPH02290876A (pt)
KR (1) KR900016207A (pt)
AT (1) ATE99310T1 (pt)
AU (1) AU622010B2 (pt)
CA (1) CA2013783A1 (pt)
DE (2) DE3911064A1 (pt)
DK (1) DK0391185T3 (pt)
ES (1) ES2062145T3 (pt)
HU (1) HUT53904A (pt)
IL (1) IL93988A0 (pt)
PT (1) PT93662A (pt)
ZA (1) ZA902627B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4022414A1 (de) * 1990-07-13 1992-01-16 Bayer Ag Substituierte pyrrolo-pyridine
DE69229839T2 (de) * 1991-01-29 2000-02-10 Mitsubishi Heavy Ind Ltd Methode zur Herstellung von Methanol unter Verwendung der Wärme eines Kernkraftwerkes
DE4405712A1 (de) * 1994-02-23 1995-08-24 Basf Ag Substituierte Naphthyridine und deren Verwendung
DE19627431A1 (de) * 1996-07-08 1998-01-15 Bayer Ag Heterocyclisch kondensierte Pyridine
AR008789A1 (es) 1996-07-31 2000-02-23 Bayer Corp Piridinas y bifenilos substituidos
PT1472228E (pt) * 2002-01-31 2009-06-24 Novartis Ag Processo para a produção de inibidores da hmg-coa reductase
MXPA05008612A (es) * 2003-02-14 2005-12-05 Smithkline Beecham Corp Compuestos novedosos.
US7420059B2 (en) 2003-11-20 2008-09-02 Bristol-Myers Squibb Company HMG-CoA reductase inhibitors and method
WO2006066512A1 (fr) 2004-12-23 2006-06-29 Zhejiang Hisun Pharma. Co., Ltd Dérivés de pyrimidinone, leur synthèse et leurs applications
US20100093738A1 (en) * 2006-10-06 2010-04-15 Basf Se Fungicidal Compounds and Fungicidal Compositions
WO2019076269A1 (zh) 2017-10-16 2019-04-25 清华大学 甲羟戊酸通路抑制剂及其药物组合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA988522A (en) * 1972-05-05 1976-05-04 Haydn W.R. Williams 1,8-naphthyridine compounds
AU535944B2 (en) * 1979-06-15 1984-04-12 Merck & Co., Inc. Hypocholestermic fermentation products from aspergillus
WO1984002131A1 (en) * 1982-11-22 1984-06-07 Sandoz Ag Analogs of mevalolactone and derivatives thereof, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals
US4613610A (en) * 1984-06-22 1986-09-23 Sandoz Pharmaceuticals Corp. Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives
PH24782A (en) * 1985-10-24 1990-10-30 Sankyo Co Composition containing a penem or carbapenem antibiotic and the use of the same
JPH07116187B2 (ja) * 1987-07-22 1995-12-13 シェリング・コーポレーション 二環式化合物、それらを薬剤として使用すること、それらの製法、およびそれらの製造に有用な中間体
US4761419A (en) * 1987-12-07 1988-08-02 Warner-Lambert Company 6-(((substituted)quinolinyl)ethyl)-and ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
DE3825611A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte annellierte pyrrole, verfahren sowie zwischenprodukte zu ihrer herstellung, und ihre verwendung in arzneimitteln, insbesondere als hmg-coa-reduktase-inhibitoren
AU634561B2 (en) * 1989-07-27 1993-02-25 Eli Lilly And Company Naphthyridine derivatives

Also Published As

Publication number Publication date
HU902098D0 (en) 1990-07-28
EP0391185A1 (de) 1990-10-10
US5034399A (en) 1991-07-23
PT93662A (pt) 1990-11-20
CA2013783A1 (en) 1990-10-06
DE3911064A1 (de) 1990-10-11
JPH02290876A (ja) 1990-11-30
HUT53904A (en) 1990-12-28
ATE99310T1 (de) 1994-01-15
AU5254290A (en) 1990-10-11
ES2062145T3 (es) 1994-12-16
DK0391185T3 (da) 1994-04-11
DE59003994D1 (de) 1994-02-10
IL93988A0 (en) 1991-01-31
AU622010B2 (en) 1992-03-26
EP0391185B1 (de) 1993-12-29
KR900016207A (ko) 1990-11-12

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