ZA896717B - Piperazinediones having a psychotropic action - Google Patents

Piperazinediones having a psychotropic action

Info

Publication number
ZA896717B
ZA896717B ZA896717A ZA896717A ZA896717B ZA 896717 B ZA896717 B ZA 896717B ZA 896717 A ZA896717 A ZA 896717A ZA 896717 A ZA896717 A ZA 896717A ZA 896717 B ZA896717 B ZA 896717B
Authority
ZA
South Africa
Prior art keywords
piperazinediones
psychotropic action
psychotropic
action
Prior art date
Application number
ZA896717A
Other languages
English (en)
Inventor
Wolf-Ulrich Nickel
Nickel Wolf-Ulrich
Rainer Henning
Henning Rainer
Wolfgang Rueger
Rueger Wolfgang
Ulrich Lerch
Lerch Ulrich
Hansjoerg Urbach
Urbach Hansjoerg
Franz Hock
Hock Franz
Gabriele Wiemer
Wiemer Gabriele
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA896717B publication Critical patent/ZA896717B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA896717A 1988-09-03 1989-09-01 Piperazinediones having a psychotropic action ZA896717B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3830096A DE3830096A1 (de) 1988-09-03 1988-09-03 Piperazindione mit psychotroper wirkung

Publications (1)

Publication Number Publication Date
ZA896717B true ZA896717B (en) 1990-05-30

Family

ID=6362300

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA896717A ZA896717B (en) 1988-09-03 1989-09-01 Piperazinediones having a psychotropic action

Country Status (13)

Country Link
US (1) US5091427A (xx)
EP (1) EP0362555A1 (xx)
JP (1) JPH02115175A (xx)
KR (1) KR900004710A (xx)
AU (1) AU627491B2 (xx)
DE (1) DE3830096A1 (xx)
DK (1) DK435289A (xx)
FI (1) FI894097A (xx)
HU (1) HU203891B (xx)
IL (1) IL91496A0 (xx)
NO (1) NO893524L (xx)
PT (1) PT91616A (xx)
ZA (1) ZA896717B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4027607A1 (de) * 1990-08-31 1992-03-05 Bayer Ag Heterocyclische verbindungen
GB9401090D0 (en) * 1994-01-21 1994-03-16 Glaxo Lab Sa Chemical compounds
GB9514465D0 (en) * 1995-07-14 1995-09-13 Glaxo Lab Sa Chemical compounds
US6143746A (en) * 1994-01-21 2000-11-07 Icos Corporation Tetracyclic cyclic GMP-specific phosphodiesterase inhibitors, process of preparation and use
ES2095811B1 (es) * 1995-07-28 1997-08-01 Univ Madrid Complutense Nuevos derivados de arilpiperazinas.
AU3079295A (en) * 1994-09-01 1996-03-22 Universidad Complutense De Madrid New arylpiperazine derivatives
ES2082727B1 (es) * 1994-09-01 1996-10-16 Univ Madrid Complutense Nuevos derivados de arilpiperazinas.
GB9514473D0 (en) * 1995-07-14 1995-09-13 Glaxo Lab Sa Chemical compounds
GB9514464D0 (en) * 1995-07-14 1995-09-13 Glaxo Lab Sa Medicaments
CZ358598A3 (cs) 1996-05-10 1999-03-17 Icos Corporation Karbolinové deriváty
GB0414093D0 (en) 2004-06-23 2004-07-28 Glaxo Group Ltd Novel compounds
JP2013509391A (ja) 2009-10-30 2013-03-14 グラクソ グループ リミテッド （３ｒ，６ｒ）−３−（２，３−ジヒドロ−１ｈ−インデン−２−イル）−１−［（１ｒ）−１−（２，６−ジメチル−３−ピリジニル）−２−（４−モルホリニル）−２−オキソエチル］−６−［（１ｓ）−１−メチルプロピル］−２，５−ピペラジンジオンの新規結晶性形態
JP2012246224A (ja) * 2011-05-25 2012-12-13 Suntory Holdings Ltd 抗認知症および学習記憶改善剤
JP6291158B2 (ja) 2012-11-21 2018-03-14 サントリーホールディングス株式会社 抗認知症および学習記憶改善剤

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3194731A (en) * 1963-03-11 1965-07-13 American Cyanamid Co Method for hypnosis and tranquilization with piperazinedione derivatives
US3384639A (en) * 1964-05-28 1968-05-21 Asahi Chemical Ind Method for producing 3, 6-dioxo-2, 5-dimethylpiperazine
CH560201A5 (en) * 1969-03-11 1975-03-27 Hoffmann La Roche 1 4-benzodiazepin derivs anti-convulsive, - muscle relaxant, tranquillising
US3644384A (en) * 1969-06-09 1972-02-22 Sterling Drug Inc Certain 2-(alpha-haloacetyl) - 1 2 3 4-tetrahydro - 9h - pyrido(3 4-b)indole-3-carboxylates and derivatives
DE2114230A1 (de) * 1971-03-24 1972-10-05 Vnii Im S Ordshonikidse Psychotropes Praeparat und Verfahren zur Herstellung seines Wirkstoffes
AR206504A1 (es) * 1972-11-03 1976-07-30 Lepetit Spa Un procedimiento para preparar 6,7,8,8a-tetrahidro-pirrol(1,2-a)pirazina-1(2h),4(3h)-dionas
WO1980000216A1 (en) * 1978-07-10 1980-02-21 Univ Illinois Inhibition by peptides of tolerance to and dependence on morphine
EP0008186A1 (en) * 1978-08-08 1980-02-20 Beecham Group Plc Cyclic diamides, a process for their preparation and their pharmaceutical compositions
US4289759A (en) * 1980-06-23 1981-09-15 Ortho Pharmaceutical Corporation Immunoregulatory diketopiperazine compounds
GB8427735D0 (en) * 1984-11-02 1984-12-12 Fujisawa Pharmaceutical Co Piperazine compound
DK181687A (da) * 1986-04-23 1987-10-24 Fujisawa Pharmaceutical Co Piperazinderivater og fremgangsmaade til fremstiling deraf

Also Published As

Publication number Publication date
HUT55394A (en) 1991-05-28
DK435289A (da) 1990-03-04
DK435289D0 (da) 1989-09-01
DE3830096A1 (de) 1990-03-15
HU203891B (en) 1991-10-28
JPH02115175A (ja) 1990-04-27
EP0362555A1 (de) 1990-04-11
AU627491B2 (en) 1992-08-27
NO893524L (no) 1990-03-05
PT91616A (pt) 1990-03-30
IL91496A0 (en) 1990-04-29
US5091427A (en) 1992-02-25
FI894097A0 (fi) 1989-08-31
KR900004710A (ko) 1990-04-12
NO893524D0 (no) 1989-09-01
AU4095789A (en) 1990-03-08
FI894097A (fi) 1990-03-04

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